Results 221 to 230 of about 80,959 (317)
Abstract INTRODUCTION Most Alzheimer's disease (AD) risk variants identified by genome‐wide association studies (GWAS) reside in noncoding regions, complicating causal interpretation. METHODS We developed PRISM‐xQTL (Pleiotropic Relationships Integrated with System‐level Multiomic QTL), integrating pleiotropy, co‐localization, Mendelian randomization ...
Nitesh Enduru, Zhongming Zhao
wiley +1 more source
Transcription factor with ambivalent role - Ralstonia eutropha's PhaR is a repressor of the phasin-gene phaP1 and an activator of phaP3. [PDF]
Cornehl P +5 more
europepmc +1 more source
Genetic inactivation of the phosphatase activity of soluble epoxide hydrolase prevents the development of pulmonary hypertension in rats, partly through upregulation of SIRT3 expression and decreased cell proliferation and apoptosis‐related proteins. Targeting sEH‐P emerges as a promising therapeutic strategy for pulmonary hypertension.
Matthieu Leuillier +17 more
wiley +1 more source
Abstract Viral infections play a significant role in cancer development, making detecting viral signatures a promising approach for early cancer diagnosis. Circulating free DNA (cfDNA), released into the bloodstream by tumors and other cells, has emerged as a powerful biomarker for non‐invasive cancer screening.
Richard Donkor Amponsah +4 more
wiley +1 more source
Mitochondrial genome of <i>Isatis indigotica</i> reveals repeat-mediated recombination and phylogenetic insights in <i>Cruciferae</i>. [PDF]
Yu S, Qin M, Fleming E, Gong X, Tang M.
europepmc +1 more source
What's new? Bladder cancer exhibits a highly heterogeneous molecular landscape and treatment response. The dysregulation of RNA modifications such as m6A has been involved in cancer initiation and progression. This study comprehensively analyzed the expression of the main catalytic component of the m6A methylation machinery in bladder tumors across one
Katerina‐Marina Pilala +10 more
wiley +1 more source
The Complete Chloroplast Genome of <i>Camellia tianeensis</i> (<i>Camellia</i> L.) and Phylogenetic Relationships with Other Plants of the Genus <i>Camellia</i>. [PDF]
Chen J, Li H, Deng L.
europepmc +1 more source
ABSTRACT Background Gestational diabetes mellitus (GDM), a common pregnancy complication characterized by maternal hyperglycemia, negatively impacts offspring health. Skeletal muscle, a critical tissue for glucose and lipid metabolism, is especially vulnerable to prenatal environmental insults.
Rui Liu +7 more
wiley +1 more source

