Results 81 to 90 of about 2,776,901 (186)

Liver‐directed drugs for transthyretin‐mediated amyloidosis

Journal of the Peripheral Nervous System, Volume 27, Issue 4, Page 228-237, December 2022., 2022
Abstract Transthyretin‐mediated amyloidosis (ATTR) is a rare, under‐recognized, progressively debilitating, fatal disease caused by the aggregation and extracellular deposition of amyloid transthyretin (TTR) fibrils in multiple organs and tissues throughout the body.
Thomas H. Brannagan 3rd, John L. Berk, Julian D. Gillmore, Mathew S. Maurer, Márcia Waddington‐Cruz, Marianna Fontana, Ahmad Masri, Laura Obici, Michela Brambatti, Brenda F. Baker, Lisa A. Hannan, Gustavo Buchele, Nick J. Viney, Teresa Coelho, Jose Nativi‐Nicolau   +14 more
wiley   +1 more source

BtrI, a novel restriction endonuclease, recognises the non-palindromic sequence 5'-CACGTC(-3/-3)-3' [PDF]

, 2000
S. Kh. Degtyarev
openalex   +1 more source

Enhancing human gut health: Global innovations in dysbiosis management

iMeta, EarlyView.
The microbiota, comprising all the microorganisms within the body, plays a critical role in maintaining good health. Dysbiosis represents a condition resulting from an imbalance or alteration of the microbiota. This study comprehensively investigates the patent literature on dysbiosis over the past 20 years.
Reda El Boukhari, Maima Matin, Latifa Bouissane, Michał Ławiński, Oleh Lushchak, Rajeev K. Singla, Michel‐Edwar Mickael, Jordi Mayneris‐Perxachs, Maria Eleni Grafakou, Shuhua Xu, Bowen Liu, Jiayi Guan, Andrzej Półtorak, Arkadiusz Szpicer, Agnieszka Wierzbicka, Nikolay T. Tzvetkov, Maciej Banach, Jarosław Olav Horbańczuk, Artur Jóźwik, Marco Cascella, Bairong Shen, Vasil Radoslavov Pirgozliev, Dongdong Wang, Olena Litvinova, Olga Adamska, Agnieszka Kamińska, Marcin Łapiński, Artur Stolarczyk, Ioana Berindan‐Neagoe, Luigi Milella, Andy Wai Kan Yeung, Prashanth Suravajhala, Anupam Bishayee, Ronan Lordan, Laszlo Barna Iantovics, Ricardo Lagoa, Monika Michalczuk, Jivko Stoyanov, A. Douglas Kinghorn, Banaz Jalil, Wolfram Weckwerth, Bey Hing Goh, Meng‐Yao Li, Gyaneshwer Chaubey, Gian Luigi Russo, Sara Frazzini, Luciana Rossi, Maurizio Battino, Wei Jia, Qi Su, Xiaoqiang Ma, Judith M. Rollinger, Simon K.‐M. R. Rittmann, Helen Sheridan, John J. Walsh, Gérard Lizard, Tomasz M. Karpiński, Ana Sanches Silva, Jakub Piwowarski, Liwei Xie, Tai‐Ping Fan, Francesca Giampieri, Adil El Midaoui, Ka‐Hing Wong, Ren‐You Gan, Ahmed Fatimi, Atanas G. Atanasov   +66 more
wiley   +1 more source

Unraveling the Palindromic and Non-Palindromic Motifs of Retroviral Integration Site Sequences by Statistical Mixture Models [PDF]

, 2022
Dalibor Miklík, Jǐŕı Grim, Daniel Elleder, Jiřı́ Hejnar   +3 more
openalex   +1 more source

Investigation on Klebsiella pneumoniae in the field of extracellular vesicles

Interdisciplinary Medicine, EarlyView.
The role of extracellular vesicles in the pathogenicity and antibiotic resistance, as well as treatment and prevention of Klebsiella pneumoniae. Abstract Klebsiella pneumoniae (KP), recognized for its pronounced antibiotic resistance, is a prevalent agent of nosocomial infections such as hospital‐acquired pneumonia.
Junwei Wu, Yuheng Liu, Jin Su, Yi Yang, Haiyi Deng, Yilin Yang, Mengxi Yanglan, Xinyi Wu, Shiqi Luo, Yao Liao, Lifu Wang   +10 more
wiley   +1 more source

Transposition of IS 1397 in the Family Enterobacteriaceae and First Characterization of ISKpn 1 , a New Insertion Sequence Associated with Klebsiella pneumoniae Palindromic Units [PDF]

, 2001
Caroline Wilde, Sophie Bachellier‐Bassi, Maurice Hofnung, Jean-Marie Clément   +3 more
openalex   +1 more source

WAS IT A MATch I SAW? Approximate palindromes lead to overstated false match rates in benchmarks using reversed sequences [PDF]

, 2023
George Glidden-Handgis, Travis J. Wheeler   +1 more
openalex   +1 more source

The GntR/VanR transcription regulator AlkR represses AlkB2 monooxygenase expression and regulates n‐alkane degradation in Pseudomonas aeruginosa SJTD‐1

mLife, EarlyView.
Abstract Transmembrane alkane monooxygenase (AlkB)‐type monooxygenases, especially AlkB2 monooxygenases, are crucial for aerobic degradation of the medium‐to‐long‐chain n‐alkanes in hydrocarbon‐utilizing microorganisms. In this study, we identified a GntR/VanR transcription regulator AlkR of Pseudomonas aeruginosa SJTD‐1 involved in the negative ...
Wanli Peng, Xiuli Wang, Qinchen Liu, Zhihong Xiao, Fulin Li, Nannan Ji, Zhuo Chen, Jiaying He, Junhao Wang, Zixin Deng, Shuangjun Lin, Rubing Liang   +11 more
wiley   +1 more source

Species-specific repetitive extragenic palindromic (REP) sequences in Pseudomonas putida [PDF]

, 2002
Isabel Aranda‐Olmedo
openalex   +1 more source

A CRISPR‐nonhomologous end‐joining‐based strategy for rapid and efficient gene disruption in Mycobacterium abscessus

mLife, EarlyView.
Abstract Mycobacterium abscessus, a fast‐growing, non‐tuberculous mycobacterium resistant to most antimicrobial drugs, causes a wide range of serious infections in humans, posing a significant public health challenge. The development of effective genetic manipulation tools for M.
Sanshan Zeng, Yanan Ju, Md Shah Alam, Ziwen Lu, H. M. Adnan Hameed, Lijie Li, Xirong Tian, Cuiting Fang, Xiange Fang, Jie Ding, Xinyue Wang, Jinxing Hu, Shuai Wang, Tianyu Zhang   +13 more
wiley   +1 more source