Results 101 to 110 of about 505,011 (403)
Targeted protein degradation in oncology: novel therapeutic opportunity for solid tumours?
Molecular Oncology, EarlyView.Current anticancer therapies are limited by the occurrence of resistance and undruggability of most proteins. Targeted protein degraders are novel, promising agents that trigger the selective degradation of previously undruggable proteins through the recruitment of the ubiquitin–proteasome machinery. Their mechanism of action raises exciting challenges,
Noé Herbel, Sophie Postel‐Vinay
wiley +1 more source
Journal of Chemistry, 2013 Four air and moisture-stable palladium(II)-Schiff base complexes, N,N′-bis(α-methylsalicylidene)propane-1,3-diamine palladium(II) (2a), N,N′-bis(4-methyl-α-methylsalicylidene)propane-1,3-diamine palladium(II) (2b), N,N′-bis(3,5-di-tert-butylsalicylidene ...
Siti Kamilah Che Soh +1 more
doaj +1 more source
Batteries, 2019 The electrochemical oxygen evolution reaction (OER) and oxygen reduction reaction (ORR) and on CNT (carbon nanotube) cathode with a palladium catalyst, palladium-coated CNT (PC-CNT), and palladium-filled CNT (PF-CNT) are assessed in an ether-based ...
Neha Chawla +4 more
doaj +1 more source
ppm Pd-catalyzed, Cu-free Sonogashira couplings in water using commercially available catalyst precursors. [PDF]
, 2019 A new catalyst that derives from commercially available precursors for copper-free, Pd-catalyzed Sonogashira reactions at the sustainable ppm level of precious metal palladium under mild aqueous micellar conditions has been developed.
Gallou, Fabrice +3 more
core
Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence
Molecular Oncology, EarlyView.The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova +18 more
wiley +1 more source
Molecular Oncology, EarlyView.The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song +11 more
wiley +1 more source
Scientific Reports, 2017 The effects of metal ion solutions (silver, copper, platinum, gold and palladium) were determined individually and in combination against Enterococcus faecium, Acinetobacter baumannii and Klebsiella pneumoniae.
Misha Y. Vaidya +4 more
doaj +1 more source
Recovery of Platinum and Palladium from Scrap Automotive Catalytic Converters
Al-Khawarizmi Engineering Journal, 2017 The hydrometallurgical method was used to platinum and palladium leaching with aqua regia solution (3HCl: HNO3). The leaching experiments were designed to obtain the optimum conditions by using Taguchi method with 16 experiments at three different ...
Mohammed Qasim Hammadi +2 more
doaj +1 more source
Laccases as palladium oxidases
Chemical Science, 2015 Combining a palladium-based complex with a laccase allows the oxidation of an alcohol substrate at room temperature and atmospheric pressure.
Mekmouche, Yasmina +7 more
openaire +5 more sources
Palladium-Catalyzed Oxidation of β-C(sp3)-H Bonds of Primary Alkylamines through a Rare Four-Membered Palladacycle Intermediate. [PDF]
, 2020 Site-selective functionalizations of C-H bonds are often achieved with a directing group that leads to five- or six-membered metallacyclic intermediates. Analogous reactions that occur through four-membered metallacycles are rare. We report a challenging
Bunescu, Ala +5 more
core +1 more source