Results 31 to 40 of about 20,716 (263)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Development of a Highly Efficient 3D RuPdBi/NG Electrocatalyst for Ethylene Glycol Oxidation in an Alkaline Media

International Journal of Electrochemical Science, 2017
Palladium (Pd) based catalysts are being considered as one of the most attractive area of research among researchers in recent years. These catalysts are used in the alcohol oxidation in fuel cells, despite it results in not enough higher oxidation ...
Yaxi Pan, Menghuan Chen, Si Wu, Yue Li, Di Lu, Hongkun Xu, Weiwei Peng, Liqun Zhou   +7 more
doaj   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

A Systematic Comparison of Alpha‐Synuclein Seed Amplification Assays for Increasing Reproducibility

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Seed amplification assays (SAAs) enable ultrasensitive detection of misfolded α‐synuclein across biofluids and tissues. Yet, heterogeneity in protocols limits cross‐study comparability and clinical translation. Here, we review α‐synuclein SAA methods and their performance across various biological matrices.
Manuela Amaral‐do‐Nascimento, Daniela F. Santos, Tuane C. R. G. Vieira, Tiago F. Outeiro   +3 more
wiley   +1 more source

Electroactive Metal–Organic Frameworks for Electrocatalysis

Advanced Functional Materials, EarlyView.
Electrocatalysis is crucial in sustainable energy conversion as it enables efficient chemical transformations. The review discusses how metal–organic frameworks can revolutionize this field by offering tailorable structures and active site tunability, enabling efficient and selective electrocatalytic processes.
Irena Senkovska, Yutong Luo, Ruyan Zhao, Jianjun Zhang, Mingchao Wang, Xinliang Feng, Eike Brunner, Stefan Kaskel   +7 more
wiley   +1 more source

Hydrodechlorination of Tetrachloromethane over Palladium Catalysts Supported on Mixed MgF2-MgO Carriers

Molecules, 2016
Pd/MgO, Pd/MgF2 and Pd/MgO-MgF2 catalysts were investigated in the reaction of CCl4 hydrodechlorination. All the catalysts deactivated in time on stream, but the degree of deactivation varied from catalyst to catalyst.
Magdalena Bonarowska, Maria Wojciechowska, Maciej Zieliński, Angelika Kiderys, Michał Zieliński, Piotr Winiarek, Zbigniew Karpiński   +6 more
doaj   +1 more source

Recent advances in Palladium(II)-catalyzed activation of aromatic ring C–H bonds

Journal of Saudi Chemical Society, 2020
Palladium is a precious metal, which has been widely used for various organic transformations in the past decades. Currently, the palladium-catalyzed direct activation of the aromatic ring C–H bonds is one of the frontier areas in organic chemistry, and ...
Yin-ling Yun, Jie Yang, Yu-hang Miao, Jie Sun, Xiao-jing Wang   +4 more
doaj   +1 more source

On‐Surface Indigo‐Based Bimolecular Coordination Networks with Programmable Regular or Vitreous Structure

Advanced Functional Materials, EarlyView.
A previously unreported coordination motif stabilising single Fe atoms by indigo chelation and pyridyl coordination on Au(111) has been revealed. By using planar tritopic pyridyl linkers (TPyB), extended 2D porous networks of indigo3(TPyB)2Fe6 form. These networks can be crystalline or vitreous and offer an environment where individual coordination ...
Hongxiang Xu, Ritam Chakraborty, Biao Yang, Dennis Meier, Joachim Reichert, Svetlana Klyatskaya, Mario Ruben, Shobhana Narasimhan, Johannes V. Barth, Anthoula C. Papageorgiou   +9 more
wiley   +1 more source

Polydimethylsiloxane Sponge-Supported Metal Nanoparticles as Reusable Catalyst for Continuous Flow Reactions

Nanomaterials, 2022
In this manuscript, polydimethylsiloxane (PDMS) sponges supporting metal nanoparticles (gold and palladium) were developed and their catalytic properties were studied through a model reaction such as the hydrogenation of p-nitrophenol.
Sergio Gómez-Graña, Marta Pita, Paula Humada-Iglesias, Jorge Pérez-Juste, Pablo Hervés   +4 more
doaj   +1 more source

Oxycyanations over Palladium Catalyst

Journal of The Japan Petroleum Institute, 1971
Acrylonitrile was obtained by the reaction of ethylene with hydrogen cyanide and oxygen over palladium or rhodium catalyst, and the reaction was named Oxycyanation. The oxycyanation of propylene Aielded a mixture of methacrylonitrile, cis- and trans-crotononitrile and allyl cyanide. The addition of hydrogen cyanide to ethylene or propylene was observed
Naoya Kominami, Hitoshi Nakajima, Nobuhiro Tamura   +2 more
openaire   +2 more sources