Results 101 to 110 of about 1,639,886 (255)

Palliative care national plan implementation through stakeholder analysis

Background: National palliative care plans depend upon stakeholder engagement to succeed. Assessing the capability, interest, and knowledge of stakeholders is a crucial step in the implementation of public health initiatives, as recommended by the World ...
Milena Buitrago Florian P, María Vargas-Escobar L, Ximena León-Delgado M, Elizabeth Muñoz Medina S, Andrade Fonseca D, Esteban Correa-Morales J., Antonio Sánchez-Cárdenas M   +6 more
core   +1 more source

TRAIP Mediates Alcohol‐Induced Liver Injury through Regulating β‐catenin Ubiquitin Degradation via Direct Interaction

Advanced Science, EarlyView.
This study reveals that NF‐κB1‐driven TRAIP upregulation in ALD correlates with disease severity. Mechanistically, TRAIP directly binds β‐catenin via its CC domain and promotes its K48‐linked ubiquitination and degradation, which is independent of the GSK3β/β‐TrCP pathway.
Zhan Wu, Mingjiang Liu, Lijuan Liao, Zhaohong Mo, Wenli Xu, Linfeng Mao, Yubing Chen, Qiuli Xie, Ming Yao, Shilian Chen, Stephen Tomlinson, Sebastian Mueller, Songqing He, Guandou Yuan   +13 more
wiley   +1 more source

Clinical Hypnosis in Palliative Care: Advanced Techniques for Effectively Relieving Pain and Symptoms.

, 2015
This work will focus on skill building for those clinicians who work with chronic and/or progressive health conditions and patients whose life feelsthreatened by medical conditions. The aim of the work is: focus on practical hypnotically approaches and
Brugnoli, Maria Paola
core   +1 more source

Palliative Surgery in General Surgery Clinics

Bezmiâlem Science, 2022
Adem AKÇAKAYA
doaj   +1 more source

Disrupted TFEB/GDNF–cAMP/ATP Coupling Underlies Astrocytic Dysfunction and Depression in LRRK2 G2019S Parkinson's Mice

Advanced Science, EarlyView.
ABSTRACT The LRRK2 G2019S mutation, a Parkinson's disease–linked variant, has been associated with depression‐like phenotypes, but mechanisms remain unclear. We chart age‐dependent behavioral changes and astrocyte reactivity in G2019S mice and define a pathway connecting LRRK2 to TFEB/GDNF signaling, cellular energetics, and inflammation.
Longping Yao, Maryam Hatami, Sumeyye Koc, Qing Jiang, Thomas Skutella, Yuanfeng Zhang   +5 more
wiley   +1 more source

Pulmonary artery banding: a 20-year experience at a tertiary care center in a developing country

Frontiers in Cardiovascular Medicine
AimPulmonary artery banding serves as an important palliative procedure used for the management of several congenital heart lesions. This study aims to describe a 20-year experience of pulmonary artery banding at a tertiary care center in a developing ...
Racha Ghoussaini, Rana Zareef, Adham Makarem, Nour Younis, Sally Al Hassan, Issam El Rassi, Munir Obeid, Fadi Bitar, Fadi Bitar, Mariam Arabi, Mariam Arabi   +10 more
doaj   +1 more source

Targeted Restoration of the Microbial Tryptophan Oxidative Pathway Ameliorates Autism‐Like Behavioral and Synaptic Deficits

Advanced Science, EarlyView.
ABSTRACT Autism Spectrum Disorder (ASD) is associated with gut microbiota dysbiosis, yet the contribution of specific microbial metabolic pathways remains unclear. Reanalysis of a public ASD cohort revealed reduced functional potential in microbial tryptophan oxidative metabolism.
Rui Guo, Caian He, Xiao Xiao, Jingmeng Li, Zilong Zhang, Ying He, Chuanchuan Wang, Jiale Zhao, Jun Gong, Jiarui Liang, Tian Yuan, Haiting Sun, Xuebo Liu, Chao Gao, Zhigang Liu   +14 more
wiley   +1 more source

Palliative Surgery

, 2022
Palliative ...
R Acosta-Rojas (13583875)
core  

Co‐Delivery of Sustained Release Chondroitinase ABC‐37 With Human iPSC‐Derived Neural Progenitors Promotes Transplant Survival and Functional Recovery in a Rodent Model of Stroke

Advanced Science, EarlyView.
A regenerative strategy for stroke combines human stem cell–derived neural progenitor cells with sustained release of a matrix‐modifying, thermostable chondroitinase ABC‐37 enzyme. In a rat model of stroke, co‐delivery enhanced transplanted cell survival and neuronal differentiation, degraded inhibitory extracellular matrix components, and improved ...
Nitzan Letko Khait, David Xinzheyang Li, Keyi Guo, Hong Cui, Quinton Sirianni, Dhana Abdo, Cindi M. Morshead, Molly S. Shoichet   +7 more
wiley   +1 more source

Ethical considerations and multidisciplinary care for pediatric patients with hypoplastic left heart syndrome: a narrative review with a systematic search

Frontiers in Cardiovascular Medicine
BackgroundHypoplastic left heart syndrome (HLHS) was a fatal congenital heart defect (CHD) until the 1980s. Introduction of the Norwood procedure and subsequent Fontan operation significantly improved survival by creating a single-ventricle circulation ...
Mojca Železnik, Urh Grošelj, Urh Grošelj, Urh Grošelj, Urh Grošelj, Petja Fister, Petja Fister, Petja Fister   +7 more
doaj   +1 more source