FGL2‐HDAC11 Drives Immunothrombosis via NETs‐Mediated Endothelial Capillarization in MASLD Fibrosis
ABSTRACT Metabolic dysfunction–associated steatotic liver disease (MASLD) is frequently accompanied by hepatic fibrosis and systemic cardiovascular complications; however, the mechanistic interplay between coagulation abnormalities and disease progression remains poorly defined.
Xitang Li +16 more
wiley +1 more source
Brazilian Society of Surgical Oncology: Guidelines and Consensus Statement for Palliative Surgery in Oncology. [PDF]
Oliveira ACF +15 more
europepmc +1 more source
Palliative Surgery or Metallic Stent Positioning for Advanced Gastric Cancer: Differences in QOL. [PDF]
Fiori E +11 more
europepmc +1 more source
Amuc_1473 Links Gut Microbes to Skeletal Homeostasis and Counteracts Multifactorial Osteoporosis
Amuc_1473, a previously uncharacterized protein enriched in Akkermansia muciniphila‐derived extracellular vesicles, is identified as a gut–bone messenger that promotes osteogenesis and inhibits osteoclastogenesis by engaging transcriptional and translational regulators in bone cells.
Shan‐Shan Rao +28 more
wiley +1 more source
Gallbladder cancer causing superior vena cava syndrome treated by palliative surgery: A case report. [PDF]
Sun J, Wang T.
europepmc +1 more source
mGluR5 in ECCCK to BLA Circuit Modulates Depressive‐Like Phenotypes through CCK Signaling
Dysregulation of mGluR5 and CCK signaling contributes to major depressive disorder, yet circuit‐level mechanisms remain unclear. Here, the ECCCK→BLA pathway is identified as a critical regulator of affective behavior. mGluR5 modulates synaptic function and CCK signaling within this circuit, controlling stress susceptibility and depressive‐like states ...
Muhammad Asim +4 more
wiley +1 more source
Clinical Outcomes of Patients Who Underwent Palliative Surgery for Spinal Metastases With and Without a History of Radiation: A Multicenter Registry Study. [PDF]
Kawamura I +54 more
europepmc +1 more source
Bone cancer pain and depression share a common origin: astrocytic A2‐to‐A1 transition in the posterior piriform cortex. This phenotypic shift disrupts the ATP–adenosine–A2AR–norepinephrine axis, simultaneously driving nociceptive and affective dysfunction.
Jiang‐Ping Liu +14 more
wiley +1 more source
The role of stereotactic radiosurgery in combination with immunotherapy for metastatic melanoma following palliative surgery: a case report and review of the literature. [PDF]
Bland S, Waldrup H.
europepmc +1 more source

