Results 191 to 200 of about 1,639,886 (255)

Unraveling the Role of Palliative Surgery in the Era of COVID-19 Pandemic. [PDF]

Indian J Palliat Care, 2020
Gupta R, Karthik AR, Rustagi K, Gupta N, Bhoriwal S, Kumar V, Garg R, Mishra S.   +7 more
europepmc   +1 more source

Gut‐Liver Translocation of Bacteroides Uniformis Alleviates Advanced Metabolic Dysfunction‐Associated Steatotic Liver Disease by Suppressing Hepatocyte Ferroptosis via Propionic Acid Secretion

Advanced Science, EarlyView.
Systematic characterization of the liver‐resident microbiota in advanced metabolic dysfunction‐associated steatotic liver disease (MASLD) reveals a consistent depletion of Bacteroides uniformis (B. uniformis) in both hepatic and gut microbial communities. Oral gavage of B.
Haiyang Liu, Zun Fan, Zhen Liu, Lei Qin, Xin Zhao   +4 more
wiley   +1 more source

Palliative surgery: state of the science and future directions. [PDF]

Br J Surg
Lilley EJ, Farber ON, Cooper Z.
europepmc   +1 more source

Targeting Tex10 Overcomes Oxaliplatin Resistance by Competitively Disrupting the Non‐Canonical BAF Complex in Colorectal Cancer

Advanced Science, EarlyView.
This study reveals that Tex10 drives oxaliplatin resistance in colorectal cancer by competitively binding BRD9 to disrupt the ncBAF complex, thereby suppressing AMBRA1 transcription and ULK1‐mediated autophagy. Gemcitabine is identified as a direct Tex10 inhibitor that restores autophagy and overcomes resistance.
Ping Xu, Jie Huang, Xiaojin Gao, Lin Deng, Yanheng Deng, Denglu Wang, Chunlei Yu, Yunxiang Zhang, Jingdong Li, Xiaocong Xiang   +9 more
wiley   +1 more source

Palliative Surgery and Potential Curative Trajectory in a Nasopharyngeal Cancer Survivor With Isolated Lung Metastasis. [PDF]

Cureus
Panuganti A, Kaul P, Kumar R, Garg PK.
europepmc   +1 more source

Clinical Complete Response after Chemotherapy and Palliative Surgery for Unresectable Gastric Cancer. [PDF]

Case Rep Oncol, 2020
Shishida M, Toyota K, Ikeda M, Karakuchi N, Inoue M, Saito Y, Takahashi T.   +6 more
europepmc   +1 more source

Renal Tubular Epithelial CRLF1 Interacts With ITGB1 to Accelerate Fibrosis During the Transition From AKI to CKD

Advanced Science, EarlyView.
During renal fibrosis, SMAD3 acts as a transcription factor for CRLF1, promoting its expression and secretion. CRLF1 then binds to ITGB1 via an autocrine mechanism, activating the PI3K‐AKT signaling pathway to mediate renal fibrosis. This accelerates the progression from AKI to CKD, highlighting the therapeutic potential of targeting CRLF1 for ...
Chunjie Wang, Yan Zhang, Fang Bai, Shankui Qian, Feng Feng, Fangyi Lu, Jiahui Fan, Kuipeng Yu, Xiangdong Yang   +8 more
wiley   +1 more source

A colostomy for large bowel obstruction at the end of life: What do patients gain from palliative surgery? [PDF]

Gynecol Oncol
Wilke RN, Iniesta MD, Fellman B, Jazaeri AA, Meyer LA, Fleming ND, Schmeler KM, Taylor JS.   +7 more
europepmc   +1 more source

Soft Hypoxia‐Adaptive Bioelectronics Integrating PEDOT:PSS/Polydopamine/Enzyme Biocomposites for Closed‐Loop Therapeutics of Chronic Wounds

Advanced Science, EarlyView.
Hypoxia‐adaptive bioelectronics based on poly(3,4‐ethylenedioxythiophene):poly(styrene sulfonate) (PEDOT:PSS)/polydopamine (PDA)/enzyme biocomposites couple O2‐centric biosensing with embedded O2 therapy to address oxygen‐deficient chronic wounds. Local O2 provision restores enzyme‐based metabolite sensing, while catalase‐mediated oxygen generation and
Songrui Liu, Bowen Yang, Cao Qi, Zhijie Zhou, Haochen Zou, Anjum Qureshi, Xiao Zhao, Ting Li, Li Gao, Ye Tao, Gang Song, Pingqiang Cai, Zheng Li, Zhiyuan Liu, Dianpeng Qi, Ting Wang, Lianhui Wang   +16 more
wiley   +1 more source

Reassessment of palliative surgery in conversion therapy of previously unresectable hepatocellular carcinoma: Two case reports and review of literature. [PDF]

World J Gastrointest Surg
Zhu YB, Qin JY, Zhang TT, Zhang WJ, Ling Q.   +4 more
europepmc   +1 more source