Identification of human papillomavirus DNA in cutaneous lesions of Cowden syndrome [PDF]
Background: Cowden syndrome (CS) or multiple hamartoma syndrome is a cancer-associated genodermatosis inherited in an autosomal dominant pattern. One of the diagnostic criteria is facial papules which are felt to be trichilemmomas, benign hair follicle ...
Burgdorf, Walter H. C. +4 more
core +1 more source
Palmoplantar Dermatoses- A Clinical Study of 300 Cases [PDF]
Introduction: Dermatoses affecting palms and soles are among the most difficult of all dermatological therapeutic problems. Many previous studies have focused on the specific diseases of palmoplantar dermatoses.
AMRITA A HONGAL +2 more
doaj +1 more source
p63 is a key regulator of iRHOM2 signalling in the keratinocyte stress response. [PDF]
Hyperproliferative keratinocytes induced by trauma, hyperkeratosis and/or inflammation display molecular signatures similar to those of palmoplantar epidermis.
Arcidiacono, P +9 more
core +2 more sources
Family C1 cysteine proteases: Biological diversity or redundancy? [PDF]
Recent progress in the identification and partial characterization of novel genes encoding cysteine proteases of the papain family has considerably increased our knowledge of this family of enzymes.
Brömme D. +4 more
core +1 more source
Mutations in desmoglein-1 cause diverse inherited palmoplantar keratoderma phenotypes:implications for genetic screening [PDF]
INTRODUCTION: The inherited palmoplantar keratodermas (PPKs) are a heterogeneous group of genodermatoses, characterised by thickening of the epidermis of the palms and soles. No classification system unites satisfactorily clinical presentation, pathology
Almutawa +16 more
core +2 more sources
Secukinumab in the treatment of psoriasis: patient selection and perspectives. [PDF]
Secukinumab is a human monoclonal antibody targeting IL-17A that has been approved for three indications: moderate-to-severe plaque psoriasis, psoriatic arthritis, and ankylosing spondylitis.
Beck, Kristen M +2 more
core +1 more source
Circumscribed palmoplantar hypokeratosis: report of two brazilian cases [PDF]
Circumscribed palmoplantar hypokeratosis is a recently recognized dermatosis and rarely reported. It was first described in 2002 and is characterized by localized loss of the horny layer in the palmoplantar area.
Lilian Kelly Rocha +1 more
doaj +1 more source
Papillon Lefevre syndrome: bridge between Dermatologist and Dentist [PDF]
Papillon-Lefevre syndrome is a rare autosomal recessively inherited condition which shows features common to both dentistry and dermatology. This disease is characterized by palmoplantar hyperkeratosis and severe periodon- titis.
Brar, Rajdeep +3 more
core +1 more source
Analysis of the human diseasome reveals phenotype modules across common, genetic, and infectious diseases [PDF]
Phenotypes are the observable characteristics of an organism arising from its response to the environment. Phenotypes associated with engineered and natural genetic variation are widely recorded using phenotype ontologies in model organisms, as are signs
Gkoutos, Georgios V +2 more
core +2 more sources
Dual Peculiarity: Two Atypical Variants of Pityriasis Rosea in a Single Patient
Pityriasis rosea (PR) is a fairly common dermatoses that we encounter in our daily practice. PR usually presents in its classical form; however, a few atypical variants have been described in the literature that may sometimes offer a diagnostic dilemma ...
Mrunalini Rayi +2 more
doaj +1 more source

