Results 51 to 60 of about 13,843 (173)

Multiclass convolutional neural network vs. 96 dermatologists in skin lesion diagnosis, an international study

open access: yesJDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background and objectives Artificial intelligence was shown to improve diagnostic accuracy for skin cancer detection. While most clinically approved models provide binary “benign/malignant” classifications, multiclass predictions may offer greater clinical utility.
Katharina Susanne Kommoss   +11 more
wiley   +1 more source

Palmoplantar keratoderma, pseudo-ainhum and knuckle pads in an African patient: A case report

open access: yesSAGE Open Medical Case Reports, 2023
Hereditary palmoplantar keratoderma is a rare heterogenous group of genodermatoses characterised by hyperkeratosis of the palms and soles. Genetic alterations affecting proteins of the keratin cytoskeleton, cornified cell envelope, desmosomes and gap ...
Kellicia Courtney Govender   +1 more
doaj   +1 more source

Persistent in vitro nociceptor hyperexcitability and axonal retraction produced by repeated paclitaxel doses

open access: yesThe FEBS Journal, EarlyView.
Repeated paclitaxel exposure causes long‐lasting nociceptor hyperexcitability and axonal retraction in adult sensory neurons. Using a long‐term primary nociceptor culture, we show that hyperexcitability is mediated by sequential upregulation of NaV1.8, TRPV1, TRPA1, and TRPM8 channels.
Angela Lamberti   +3 more
wiley   +1 more source

Onychoscopy in Palmoplantar Psoriasis: A Comparative Study of Nonpustular Palmoplantar Psoriasis and Palmoplantar Pustulosis

open access: yesDermatology Practical & Conceptual
Introduction: Palmoplantar psoriasis (PP) is classified as nonpustular psoriasis (NPPP) or palmoplantar pustulosis (PPP). Objective: We sought to shed light on the phenotypic diversity of nail psoriasis (NP) and conducted a thorough study of the ...
Ahu Yorulmaz
doaj   +1 more source

The Psoriasis–Eczema Interface: Clinical Classification and Therapeutic Implications From a Bicentric Experience

open access: yesInternational Journal of Dermatology, EarlyView.
The psoriasis–atopic dermatitis interface: four clinical phenotypes (coexisting, overlapping, biologic‐induced eczema, dupilumab‐induced psoriasis) across 105 patients from two Italian tertiary centers. JAK inhibitors achieved the highest response rates across all phenotypes, reflecting their mechanistic rationale targeting shared JAK‐STAT downstream ...
Michela D'Agostino   +8 more
wiley   +1 more source

A case of palmoplantar dysesthesia syndrome caused by capecitabine

open access: yes, 2016
Palmoplantar dysesthesia is a dermatologic toxic reaction caused by chemotherapeutics. Also known as hand-foot syndrome, it is not life-threatening, but does decrease quality of life.
Aktas, Akin   +4 more
core   +1 more source

Hyperkeratotic palmoplantar lichen planus in a child

open access: yesIndian Journal of Dermatology, 2013
Lichen planus (LP) is a common idiopathic inflammatory disorder that affects the flexor aspect of the wrists, the legs, and the oral and genital mucosa. Depending upon the site of involvement, LP can be divided into mucosal, nail, scalp, or palmoplantar ...
Bhushan Madke   +3 more
doaj   +1 more source

Nodular Secondary Syphilis: Systematic Review of an Underrecognized Clinical Phenotype

open access: yesInternational Journal of Dermatology, EarlyView.
Nodular secondary syphilis is a rare and often misdiagnosed manifestation of secondary syphilis with diverse clinical and histopathologic features. This systematic review of 144 cases highlights its frequent association with ulceration, generalized skin involvement, and HIV infection, emphasizing the importance of considering syphilis in the ...
Jacopo Tartaglia   +4 more
wiley   +1 more source

Mal de Meleda : a case successfully treated with acitretin

open access: yesPAMJ Clinical Medicine, 2020
Mal de Meleda (MdM) is an autosomal recessive form of palmoplantar keratoderma, that is characterized by transgradient keratoderma with associated scleroatrophy, nail changes, pseudoainhum around digits and perioral erythema, without a tendency for ...
Kaoutar Achehboune   +3 more
doaj   +1 more source

Ulceronecrotic Plaques, Patchy Scalp Alopecia and Visual Disturbance in a 46‐Year‐Old Man

open access: yesInternational Journal of Dermatology, EarlyView.
ABSTRACT A 46‐year‐old incarcerated man with chronic hepatitis C infection and intravenous drug use presented with a rapidly progressive pruritic eruption involving the scalp, trunk, and limbs, accompanied by patchy scalp alopecia and bilateral panuveitis.
Alex Majri   +3 more
wiley   +1 more source

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