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Synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome is a rare inflammatory disorder with multiple phenotypes. The syndrome has identifiable radiologic characteristics that are the most important when making a diagnosis.
Hideyuki Kinoshita +9 more
doaj +1 more source
Secukinumab in the treatment of psoriasis: patient selection and perspectives. [PDF]
Secukinumab is a human monoclonal antibody targeting IL-17A that has been approved for three indications: moderate-to-severe plaque psoriasis, psoriatic arthritis, and ankylosing spondylitis.
Beck, Kristen M +2 more
core +1 more source
Possible Efficacy of Vedolizumab, an Anti-α4β7 Integrin Antibody, in Palmoplantar Pustulosis
Palmoplantar pustulosis (PPP) is a chronic skin inflammatory disease in which blisters and pustules repeatedly develop on palms and soles. PPP is often refractory to topical therapy, oral therapy, phototherapy, and biologics that are usually applied for ...
Hitoshi Terui +4 more
doaj +1 more source
Chronic Mercury Intoxication Masquerading as Systemic Disease: A Case Report and Review of the Literature [PDF]
Background: Mercury is a highly toxic environmental metal that exists in three different forms: elemental, inorganic and organic. Intoxication occurs in either occupational or non-occupational settings, mainly after the inhalation of vapour and fumes in ...
Aouad, Krystel +4 more
core +2 more sources
Interventions for chronic palmoplantar pustulosis [PDF]
Palmoplantar pustulosis is a chronic inflammatory disease in which sterile, relapsing pustules appear on the palms and soles, possibly in conjunction with other symptoms. The previous Cochrane Review on this topic was published in 2006, before biological treatments were extensively used.To assess the effects of interventions for chronic palmoplantar ...
Obeid, Grace +5 more
openaire +3 more sources
Association of Clinical and Demographic Factors With the Severity of Palmoplantar Pustulosis. [PDF]
Importance: Although palmoplantar pustulosis (PPP) can significantly impact quality of life, the factors underlying disease severity have not been studied. Objective: To examine the factors associated with PPP severity. Design, Setting, and Participants:
Barker, Jonathan N. +32 more
core +2 more sources
Treatment recommendations for psoriatic arthritis [PDF]
Objective: To develop comprehensive recommendations for the treatment of the various clinical manifestations of psoriatic arthritis (PsA) based on evidence obtained from a systematic review of the literature and from consensus opinion.
Boehncke, Wolf-Henning +14 more
core +3 more sources
Palmoplantar pustulosis and IgA nephropathy [PDF]
We present a case of IgA nephropathy complicated with palmoplantar pustulosis. The skin lesion improved with tonsillectomy. The purposes of this article were to aid physicians in understanding that (a) IgA nephropathy should be considered in patients with palmoplantar pustulosis and (b) patients with these diseases should be referred to otolaryngology ...
Yoshinosuke Shimamura +2 more
openaire +2 more sources
Research progress on phosphodiesterase 4 inhibitors in the treatment of palmoplantar pustulosis
Palmoplantar pustulosis (PPP) is a chronic recurrent inflammatory skin disease. Existing therapeutic methods cannot meet the demand by patients. Phosphodiesterase-4 (PDE-4) is a key enzyme involved in the balance of immunocytes.
YAO Xinyi +3 more
doaj +1 more source
Transient hypercalcemia in a patient with SAPHO syndrome
We here report a case of SAPHO (synovitis‐acne‐pustulosis‐hyperostosis‐osteitis) syndrome with hypercalcemia. The patient was diagnosed with SAPHO syndrome at the age of 54, because he exhibited osteitis and hyperostosis around the sternoclavicular ...
Tadashi Yoshida, Mototsugu Oya
doaj +1 more source

