Results 1 to 10 of about 1,382 (156)

Family aggregation and prevalence of other autoimmune diseases in SAPHO syndrome [PDF]

Heliyon, 2023
Objective: SAPHO (Synovitis, Acne, Pustulosis, Hyperostosis and Osteitis) syndrome is a heterogeneous disease that clinically manifests as chronic inflammatory osteoarticular and dermatological lesions.
Chen Li, Hesong Wang, Haixu Jiang, Yuming Shao, Guangrui Huang, Kai Yuan, Shufeng Wei   +6 more
doaj   +4 more sources

SAPHO Syndrome Presenting With Severe Inflammatory Back Pain (Sacroiliitis) and Rare Retinol Associated Myopathy in an Iraqi Adolescent Male: A Case Report and Literature Review [PDF]

Clinical Case Reports
SAPHO syndrome is a rare autoinflammatory disorder characterized by synovitis, acne, pustulosis, hyperostosis, and osteitis. Although musculoskeletal and dermatologic manifestations are well recognized, extra‐articular involvement remains uncommon ...
Farah Jaafar Mahdi, Ali Saad Al‐Shammari, Mustafa Majid Hameed, Marwah Sami Ahmed, Ibrahim Khalil, Zahraa Saeed Fahad, Ahmed Dahham Hasan, Nizar Abdulateef Jassim   +7 more
doaj   +3 more sources

JAK Inhibitors for Treatment of SAPHO Syndrome: A Systematic Review of 72 Cases [PDF]

ACR Open Rheumatology
Objective Synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome usually involves bones, joints, and skin. Due to a lack of known pathogenesis and clinical trials, there is no standard treatment of SAPHO syndrome.
Patrick Fazeli, Saeed Bahramian, Kimia Farahmand, Hamed Ghoshouni, Yalda Farahmand, Amirali Soheili, Leyla Bagheri, Huria Memari, Aydin Feyzi, Seyed Mohammad Vahabi   +9 more
doaj   +3 more sources

SAPHO Syndrome Complicated by Ankylosing Spondylitis Successfully Treated With Tofacitinib: A Case Report

Frontiers in Immunology, 2022
Synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome, a type of chronic inflammatory disease, is rare and difficult to treat. Osteoarthropathy with skin involvement is the primary clinical manifestation of SAPHO syndrome.
Fangfang Yuan, Jing Luo, Qiong Yang
doaj   +3 more sources

Evaluation of tonsillectomy in the treatment of SAPHO syndrome: past evidence and future directions [PDF]

Frontiers in Medicine
Synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome is a rare aseptic inflammatory clinical syndrome characterized by widespread skin lesions and bone-joint lesions.
Wen-Yuan Gan, Ben-Hong Ren, Qing-Ping Zhang, Yi Wang   +3 more
doaj   +2 more sources

Upadacitinib in the treatment of SAPHO syndrome: a case report [PDF]

Frontiers in Immunology
Synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome, a rare autoinflammatory disease, is usually defined by musculoskeletal symptoms and cutaneous manifestations.
Yanran Yang, Zhanxue Sun, Yongpeng Ge
doaj   +2 more sources

Clinical Images: Successfully treated mandibular osteomyelitis by tumor necrosis factor inhibitor in SAPHO syndrome. [PDF]

Arthritis Rheumatol
Arthritis &Rheumatology, Volume 78, Issue 4, Page 993-994, April 2026.
Oba S, Hosoya T, Yasuda S, Yokoyama K, Tomioka H, Harada H.   +5 more
europepmc   +2 more sources

Postpartum lumbopelvic pain could be SAPHO syndrome: a case report [PDF]

Frontiers in Immunology
BackgroundSynovitis–acne–pustulosis–hyperostosis–osteitis (SAPHO) syndrome is a rare autoimmune disorder. The involvement of spinal and sacroiliac joint in SAPHO syndrome closely resembles the manifestations of postpartum lumbopelvic pain (LPP).Case ...
Zheng Weiwei, Zhang Junhong, Zhang Rong
doaj   +2 more sources

The role of cytokines in the pathogenesis of SAPHO syndrome [PDF]

Frontiers in Immunology
SAPHO syndrome is a complex inflammatory disorder affecting the skin and bones, characterized by osteomyelitis, acne, and pustulosis. Cytokines play a pivotal role in the pathogenesis of SAPHO syndrome, especially in inflammatory responses and immune ...
Yi Yang, Yi Yang, Qianzhu Chen, Qianzhu Chen, Weiyang Zhong, Weiyang Zhong   +5 more
doaj   +2 more sources

Familial clustering of SAPHO syndrome. [PDF]

Cent Eur J Immunol
In a novel investigation of familial aggregation in SAPHO syndrome, a rare chronic autoinflammatory disorder characterized by the acronym synovitis, acne, pustulosis, hyperostosis, and osteitis, we identified a unique familial cohort with four affected individuals, including a male, marking the first report of male familial involvement in the ...
Gu M, Zheng Z, Zhang C, Zhang Y, Wu Y, Li C.   +5 more
europepmc   +4 more sources