Results 41 to 50 of about 1,389 (157)
The Journal of Dermatology, EarlyView.ABSTRACT Pustulotic arthro‐osteitis (PAO) is a clinically important osteoarticular comorbidity affecting approximately 9%–28% of patients with palmoplantar pustulosis (PPP), yet early recognition and standardized activity assessment remain challenging, particularly in routine dermatology practice.
Taiki Nozaki +8 more
wiley +1 more source
International Journal of Dermatology, EarlyView.Development and preliminary validation of the Early Sacroiliitis Screening Tool (ESHST), a dermatology‐oriented screening questionnaire for identifying hidradenitis suppurativa patients at increased risk of spondyloarthritis. ABSTRACT Background Hidradenitis suppurativa (HS) is increasingly recognized as a systemic inflammatory disease associated with ...
Umut Bakay +3 more
wiley +1 more source
Emerging Roles of PSTPIP2 in Autoimmunity: From Mechanism to Therapeutic Implications
Immunology, EarlyView.PSTPIP2 acts as a key brake on myeloid inflammation by suppressing IL‐1β‐driven signalling, macrophage dysregulation and inflammation‐associated bone remodelling. Its emerging roles in CRMO/CMO, rheumatoid arthritis, SAPHO syndrome and bullous pemphigoid support its potential as a biomarker and therapeutic target.
Erdong Zhang +9 more
wiley +1 more source
Failure of tocilizumab in treating two patients with refractory SAPHO syndrome: a case report
Journal of International Medical Research, 2018 Synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome is a rare autoinflammatory disease with no standard treatment. Interleukin (IL)-6 inhibitors represent a novel therapeutic option for rheumatoid arthritis and some autoinflammatory ...
Xiao-Chuan Sun +7 more
doaj +1 more source
Journal of International Medical Research, 2021 Synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome is an umbrella term covering a constellation of bone lesions and skin manifestations, but has rarely been clarified in the clinic.
Cheng Qiu +7 more
doaj +1 more source
Clinical Case Reports, Volume 14, Issue 8, August 2026.ABSTRACT Chronic Recurrent Multifocal Osteomyelitis (CRMO) is a rare autoinflammatory bone disorder that primarily affects children and adolescents. It is characterized by recurrent episodes of bone pain with sterile inflammatory lesions, often resembling infection or malignancy.
Dosti Regmi +4 more
wiley +1 more source
Journal of Children's Orthopaedics, 2015 Introduction Synovitis–acne–pustulosis–hyperostosis–osteitis (SAPHO) is an acronym for various osteoarticular and dermatological manifestations that can appear in the same patient. It is a rare syndrome, but since its awareness has increased, there have been more and more such reports in the literature.
openaire +2 more sources
Spondyloarthritis Associated With Collagenous Colitis—Case Report and Literature Review
Clinical Case Reports, Volume 14, Issue 5, May 2026.ABSTRACT Collagenous colitis (CC) is a subtype of microscopic colitis characterized by chronic watery diarrhea with normal endoscopic findings. Although often linked to autoimmune diseases, its association with spondyloarthropathy (SpA) is rare and poorly documented.
Charlotte Bouvy +4 more
wiley +1 more source
Orphanet Journal of Rare Diseases, 2022 Key messages 1. Most employed SAPHO syndrome patients experienced decreased work productivity and activity. 2. There were statistically significant correlations between WPAI outcomes and other disease-related measures. 3.
Chen Li +8 more
doaj +1 more source
United European Gastroenterology Journal, Volume 14, Issue 4, May 2026.ABSTRACT Background Upadacitinib (UPA) is the first oral Janus kinase (JAK) inhibitor approved for the treatment of Crohn's disease (CD). Real‐world data, particularly from large nationwide cohorts, remain limited. This study aimed to evaluate the real‐world effectiveness, safety, and treatment persistence of UPA in patients with CD.
M. Iborra +51 more
wiley +1 more source