Results 61 to 70 of about 1,389 (157)

A Case of Neutrophilic Dermatoses-Sweet’s Syndrome Coexisting with SAPHO Syndrome

Clinical, Cosmetic and Investigational Dermatology, 2023
Mingwei Ma,1,* Shufeng Wei,2,* Dan Yin,2 Weizhong Li,2 Chen Li2 1School of Clinical Medicine, Peking Union Medical College Hospital (PUMC and CAMS), Beijing, 100730, People’s Republic of China; 2Department of Rheumatology, Fangshan Hospital ...
Ma M, Wei S, Yin D, Li W, Li C
doaj  

JAK Inhibitors for Treatment of Pyoderma Gangrenosum and Sweet Syndrome: A Systematic Review of Published Case Reports

Dermatology Research and Practice, Volume 2026, Issue 1, 2026.
Neutrophilic dermatoses, including pyoderma gangrenosum (PG) and Sweet syndrome (SS), are inflammatory disorders characterized by neutrophilic infiltration without infection. Conventional therapies are often inadequate. We aim to evaluate the efficacy and safety of JAK inhibitors (JAK‐I) in the treatment of PG and SS. The study was registered (PROSPERO‐
Seyed Mohammad Vahabi, Sama Heidari, Yalda Farahmand, Elnaz Pourgholi, Nika Kianfar, Huria Memari, Farzad Esmaeili, Saeed Bahramian, Ifa Etesami, Mahshid Sadat Ansari, Anjali Chauhan   +10 more
wiley   +1 more source

Clinical Efficacy and Safety of Photodynamic Therapy for Treating Rosacea: A Systematic Review and Meta‐Analysis

Dermatologic Therapy, Volume 2026, Issue 1, 2026.
To assess the efficacy and safety of photodynamic therapy (PDT) for the treating rosacea, seven databases were systematically searched for relevant studies from 1963 to 2025. At last, 23 studies involving 1439 participants were included. In the 17 randomized controlled trials (RCTs) included, PDT all demonstrated considerable efficacy without obvious ...
Yuqiu Lin, Guang Li, Yongjun Zhu, Yan Li, Ting Lai, Shiyang Li, Xiaohua Tao, Suraiya Saleem   +7 more
wiley   +1 more source

Off‐Label Use of Selective JAK1 Inhibitors in Immune‐Mediated Inflammatory Skin Diseases: A Retrospective Case Series

Dermatologic Therapy, Volume 2026, Issue 1, 2026.
This article aimed to evaluate the efficacy and safety of JAK1 inhibitors (abrocitinib and upadacitinib) in off‐label treatment of refractory inflammatory skin diseases. We retrospectively analyzed 19 patients with various immune‐mediated dermatoses, including cutaneous lichen planus, parapsoriasis, vitiligo, autoimmune bullous diseases ...
Si Zhang, Xinnuo Chen, Maoying Li, Xi Wang, Cuihong Lian, Aditya Gupta   +5 more
wiley   +1 more source

Expression of tumor necrosis factor-alpha converting enzyme and matrix metalloproteinase-3 in proliferated synovium in a patient with synovitis-acne-pustulosis-hyperostosis-osteitis syndrome: a case report

Journal of Medical Case Reports, 2009
Introduction Synovitis-acne-pustulosis-hyperostosis-osteitis (SAPHO) syndrome is a rare disorder. The etiology remains unknown and the treatment is still empirical.
Komiya Koichiro, Yamada Harumoto, Terada Nobuki, Mizoguchi Yoshikazu, Yamada Mitsuko, Suzuki Masashi, Kato Shinichi   +6 more
doaj   +1 more source

Expert consensus on early diagnosis and treatment of psoriatic arthritis (2025 edition)

Rheumatology &Autoimmunity, Volume 5, Issue 4, Page 241-257, December 2025.
Psoriatic arthritis (PsA) is a chronic inflammatory musculoskeletal disease associated with psoriasis. PsA is characterized by diverse clinical manifestations and often follows a protracted, relapsing course, potentially leading to joint deformity and disability.
Ranran Yao, Lin Cai, Liling Xu, Yuhui Li, Yuan Jia, Yin Su, Chinese Expert Consensus Research Group on Early Recognition, Diagnosis and Treatment of Psoriatic Arthritis   +7 more
wiley   +1 more source

Biologic‐Induced Paradoxical Psoriatic Alopecia: A Systematic Review

Australasian Journal of Dermatology, Volume 66, Issue 8, Page 441-447, December 2025.
ABSTRACT A systemic review was completed of primary research articles reporting patient outcomes in paradoxical psoriatic alopecia in association with biologic therapy. Our search strategy identified 96 patients from 45 studies in addition to our own case.
Yaron Gu, Deshan F. Sebaratnam, Mani Makhija, Joshua Farrell   +3 more
wiley   +1 more source

Case Report: Successful treatment of refractory synovitis, acne, pustulosis, hyperostosis, and osteitis syndrome and palmoplantar pustulosis with ustekinumab

Frontiers in Immunology
Synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome is a rare chronic inflammatory disease mainly manifested as skin and osteoarticular lesions.
Luxia Chen, Qichang Liang, Sijia Chen, Hao Cheng   +3 more
doaj   +1 more source

Depression in patients with SAPHO syndrome and its relationship with brain activity and connectivity

Orphanet Journal of Rare Diseases, 2017
Background Synovitis-acne-pustulosis-hyperostosis-osteitis (SAPHO) syndrome is a rare disease and there is no related literature concerning psychiatric symptoms in SAPHO patients.
Jie Lu, Yanping Duan, Zhentao Zuo, Wenrui Xu, Xuewei Zhang, Chen Li, Rong Xue, Hanzhang Lu, Weihong Zhang   +8 more
doaj   +1 more source

SAPHO syndrome and pustular skin diseases: shared inflammatory circuits, divergent tissue outcomes, and the limits of a spectrum model

Frontiers in Immunology
Both SAPHO (synovitis, acne, pustulosis, hyperostosis, and osteitis) syndrome and pustular skin diseases are characterized by neutrophil-dominated inflammatory responses; however, whether they represent manifestations within a shared disease spectrum ...
Rongzhen Xia, Kaining Gao, Yishu Zhao, Yiting Lin, Qingrui Yang, Qingrui Yang, Wei Xu, Wei Xu   +7 more
doaj   +1 more source