Results 71 to 80 of about 1,143,866 (185)

JAK Inhibitors for Treatment of Pyoderma Gangrenosum and Sweet Syndrome: A Systematic Review of Published Case Reports

open access: yesDermatology Research and Practice, Volume 2026, Issue 1, 2026.
Neutrophilic dermatoses, including pyoderma gangrenosum (PG) and Sweet syndrome (SS), are inflammatory disorders characterized by neutrophilic infiltration without infection. Conventional therapies are often inadequate. We aim to evaluate the efficacy and safety of JAK inhibitors (JAK‐I) in the treatment of PG and SS. The study was registered (PROSPERO‐
Seyed Mohammad Vahabi   +10 more
wiley   +1 more source

Clinical Efficacy and Safety of Photodynamic Therapy for Treating Rosacea: A Systematic Review and Meta‐Analysis

open access: yesDermatologic Therapy, Volume 2026, Issue 1, 2026.
To assess the efficacy and safety of photodynamic therapy (PDT) for the treating rosacea, seven databases were systematically searched for relevant studies from 1963 to 2025. At last, 23 studies involving 1439 participants were included. In the 17 randomized controlled trials (RCTs) included, PDT all demonstrated considerable efficacy without obvious ...
Yuqiu Lin   +7 more
wiley   +1 more source

L'utilisation des biothérapies dans le syndrome SAPHO

open access: yes, 2021
The SAPHO syndrome is a rare auto-inflammatory disease characterized mainly by the simultaneous presence or not of synovitis, acne, pustulosis, hyperostosis and osteitis wich contitute its acronyme. Since its "discovery", no so-called "classic" treatment
Przybylowski, Sophie
core  

Expression of tumor necrosis factor-alpha converting enzyme and matrix metalloproteinase-3 in proliferated synovium in a patient with synovitis-acne-pustulosis-hyperostosis-osteitis syndrome: a case report

open access: yesJournal of Medical Case Reports, 2009
Introduction Synovitis-acne-pustulosis-hyperostosis-osteitis (SAPHO) syndrome is a rare disorder. The etiology remains unknown and the treatment is still empirical.
Komiya Koichiro   +6 more
doaj   +1 more source

Off‐Label Use of Selective JAK1 Inhibitors in Immune‐Mediated Inflammatory Skin Diseases: A Retrospective Case Series

open access: yesDermatologic Therapy, Volume 2026, Issue 1, 2026.
This article aimed to evaluate the efficacy and safety of JAK1 inhibitors (abrocitinib and upadacitinib) in off‐label treatment of refractory inflammatory skin diseases. We retrospectively analyzed 19 patients with various immune‐mediated dermatoses, including cutaneous lichen planus, parapsoriasis, vitiligo, autoimmune bullous diseases ...
Si Zhang   +5 more
wiley   +1 more source

Paradoxical SAPHO syndrome observed during anti-TNF-α therapy for Crohn's disease

open access: yes, 2017
Hitoshi Amano,1 Reikei Matsuda,1 Tomohiko Shibata,2 Daisuke Takahashi,1 Shinichiro Suzuki3 1Department of Gastroenterology, Fujisawa Shonandai Hospital, Fujisawa, 2Division of Rheumatology, Department of Internal Medicine, St Marianna University School ...
Amano H   +4 more
core  

Expert consensus on early diagnosis and treatment of psoriatic arthritis (2025 edition)

open access: yesRheumatology &Autoimmunity, Volume 5, Issue 4, Page 241-257, December 2025.
Psoriatic arthritis (PsA) is a chronic inflammatory musculoskeletal disease associated with psoriasis. PsA is characterized by diverse clinical manifestations and often follows a protracted, relapsing course, potentially leading to joint deformity and disability.
Ranran Yao   +7 more
wiley   +1 more source

A rare case of back pain: sapho syndrome

open access: yes, 2021
Back pain is one of the most common reasons for outpatient visits but is rarely severe enough to require hospitalization. Synovitis-acne-pustulosis-hyperostosis-osteitis (SAPHO) syndrome, a chronic inflammatory disorder is one of the rare causes of back ...
Boppana, Leela Krishna Teja   +3 more
core   +1 more source

Case Reports - SAPHO syndrome treated with pamidronate

open access: yes, 2005
A middle aged man presented with a 4 year history of painful swelling of both knees and pustular acne on his back. The MRI scan of the knees showed gross synovitis, so did the histopathology of the synovium.
Tehrani Rustom
core   +2 more sources

Clinical and Radiological Identification and Management of SAPHO Syndrome. [PDF]

open access: yesHCA Healthc J Med
INTRODUCTION: Synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome is an autoinflammatory disease whose acronymic name stands for the symptoms commonly seen in the disease.
Al-Housni O   +3 more
europepmc   +2 more sources

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