Results 1 to 10 of about 1,534 (98)

Characteristics of SAPHO Syndrome: Clinical Analysis of 19 Cases [PDF]

Zhongguo quanke yixue, 2022
Background SAPHO syndrome is a rare chronic inflammatory disease of unknown causes with various clinical manifestations, which involves bone joint and skin tissue, and has no specific diagnostic indicators and uniform treatment strategy.
Wenting SUN, Qiuai KOU
doaj   +1 more source

SAPHO—a diagnosis to consider in patients with refractory costochondritis

Egyptian Rheumatology and Rehabilitation, 2022
Background SAPHO syndrome (synovitis, acne, pustulosis, hyperostosis, and osteitis) is a rare, heterogeneous, self-limited disease of unknown etiology. It involves progressive bone and joint damage, and skin and bone lesions may occur at different times ...
Viviana Parra-Izquierdo, Hector Cubides, Viviana Rivillas, Juan Sebastián Frías-Ordoñez, Sergio Mora, Joerg Ermann   +5 more
doaj   +1 more source

Clinical Presentation of Schnitzler’s Syndrome: A Rare Autoimmune Disease

Journal of Investigative Medicine High Impact Case Reports, 2023
Schnitzler’s Syndrome (SS) is a rare late-onset acquired autoinflammatory disorder which consists of chronic urticaria associated with a monoclonal IgM-kappa gammopathy, arthralgias, skeletal hyperostosis, lymphadenopathy, and recurrent constitutional ...
Vishal Patel MD, Darshana Balasubramaniam MD, Vanessa Cavero-Chavez MD, Lyda Cuervo-Pardo MD, Catalina Sanchez-Alvarez MD   +4 more
doaj   +1 more source

Skin symptoms as diagnostic clue for autoinflammatory diseases [PDF]

Anais Brasileiros de Dermatologia, 2017
Autoinflammatory disorders are immune-mediated diseases with increased production of inflammatory cytokines and absence of detectable autoantibodies.
Alvaro Moreira, Barbara Torres, Juliano Peruzzo, Alberto Mota, Kilian Eyerich, Johannes Ring   +5 more
doaj   +2 more sources

Do you know this syndrome? Você conhece esta síndrome?

Anais Brasileiros de Dermatologia, 2012
The SAPHO syndrome (synovitis, acne, pustulosis, hyperostosis and osteitis) includes a group of findings characterized by bone lesions usually located on the anterior chest wall, often associated with skin lesions.
Gerson Dellatorre, Caio César Silva de Castro   +1 more
doaj   +1 more source

Synovitis, Acne, Pustulosis, Hyperostosis, and Osteitis Syndrome: A Case of Spine, Pelvis, and Anterior Chest Wall Involvement, with Overlooked Plantar Pustulosis

대한영상의학회지, 2017
Synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome is an inflammatory clinical condition with aseptic bone lesions and characteristic skin manifestations.
Hyun Soo Kim, Soh Yong Jeong, Sujin Lee, In-Woon Baek, Jeongmi Park   +4 more
doaj   +1 more source

Clinical and scintigraphic improvement of mandibular involvement associated with chronic nonbacterial osteitis following an interleukin-23 inhibitor: a case-based literature review

Immunological Medicine
Chronic nonbacterial osteitis (CNO) occasionally presents with severe and refractory mandibular involvement, conventionally called as diffuse sclerosing osteomyelitis.
Koji Suzuki, Mitsuhiro Akiyama, Koichi Saito, Hiroshi Takei, Yuko Kaneko   +4 more
doaj   +1 more source

Exploratory MRI and Clinical Marker Analysis of Pustulotic Arthro‐Osteitis Disease Activity From a Phase 3 Brodalumab Trial

The Journal of Dermatology, EarlyView.
ABSTRACT Pustulotic arthro‐osteitis (PAO) is a clinically important osteoarticular comorbidity affecting approximately 9%–28% of patients with palmoplantar pustulosis (PPP), yet early recognition and standardized activity assessment remain challenging, particularly in routine dermatology practice.
Taiki Nozaki, Manabu Arai, Junko Ochi, Mona Uchida‐Yamada, Masahiro Hashimoto, Mitsuhiro Akiyama, Yuko Kaneko, Yasumasa Kanai, Masahiro Jinzaki   +8 more
wiley   +1 more source

Computed tomography in terms of thoracic outlet syndrome diagnosis

Исследования и практика в медицине
Thoracic outlet syndrome (TOS) comprises a group of clinical syndromes caused by congenital or acquired compression of the brachial plexus or subclavian vessels during their passage through the superior thoracic aperture.Clinical manifestations vary by ...
L. A. Titova, A. A. Gridsay, E. M. Tolstykh, S. I. Marks, N. V. Ischenko, M. V. Anisimov, A. Yu. Goncharova, I. A. Baranov, L. A. Haetskaya   +8 more
doaj   +1 more source

Sclerostin regulates bone morphogenetic protein (BMP) bioavailability through interactions with BMP complexes and fibrillin microfibrils

The FEBS Journal, EarlyView.
Sclerostin (SOST) is a multifunctional extracellular modulator of BMP and Wnt signaling. SOST binds with high affinity to fibrillin‐1 and fibrillin‐2, localizing it to fibrillin microfibrils and regulating its extracellular bioavailability. Fibrillin‐bound SOST cannot engage BMP‐7 prodomain (PD) complexes, revealing a competitive mechanism that ...
Annkatrin Correns, Fady Marcous, Steffen Lütke, Matthias Mörgelin, Philipp Barnowski, Ariane G. Furlan, Nathalie H. Schröder, Bodo Levkau, Sarah Riek, Martin Mollenhauer, Manuel Koch, Gerhard Sengle   +11 more
wiley   +1 more source