Results 11 to 20 of about 1,454 (104)

Melorheostosis: Clinical, radiological, and histopathological features with a literature review. [PDF]

Physiol Rep
Abstract Melorheostosis is a rare sclerosing bone dysplasia that can clinically and radiologically mimic common bone disorders, particularly in atypical presentations. Its heterogeneous manifestations and limited awareness among clinicians frequently contribute to diagnostic delays or misdiagnosis. We report the case of a 34‐year‐old woman with chronic
Koca E, Kavak Ş, Demir B, Comunoglu N, Kantarci F, Koca O.   +5 more
europepmc   +2 more sources

Cumulative effects of lifelong systemic excess growth hormone on postcranial skeletal morphology in adult mice

Journal of Anatomy, EarlyView.
Our μCT‐based pilot study reveals size and shape disparity in the adult postcranial skeleton of growth‐hormone model (bGH) mice relative to wild‐type mice. bGH mice have larger and more sexually dimorphic bones, with a systemic radiodensity increase in bony sesamoids and associated, but typically uncalcified, soft tissues.
Joseph R. Groenke, Huanhuan Liu, Grace Lach, Abhishek Wajpe, Darlene Berryman, John J. Kopchick, Shouan Zhu, Patrick M. O'Connor   +7 more
wiley   +1 more source

Unveiling Saint Theobald: A Multidisciplinary Bioanthropological Investigation

International Journal of Osteoarchaeology, Volume 36, Issue 4, Page 945-953, July/August 2026.
ABSTRACT Saint Theobald of Provins (1033–1066), a French nobleman who embraced voluntary poverty, hermitism, and pilgrimage, represents an early figure in the medieval ascetic movement. He holds historical significance for the diffusion of 11th‐century ascetic ideals, as a hermit saint associated with the Camaldolese order and venerated across northern
Nicola Carrara, Cicero Moraes, Luca Bezzi, Alberto Zanatta, Luca Pagani, Gilberto Artioli, Cinzia Scaggion   +6 more
wiley   +1 more source

Bilateral Avascular Necrosis of the Femoral Heads in Ankylosing Spondylitis Requiring Staged Total Hip Arthroplasty: A Case Report of Diagnostic and Therapeutic Challenges

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Ankylosing spondylitis (AS) is a chronic immune‐mediated inflammatory arthropathy primarily affecting the axial skeleton but may involve peripheral joints, particularly the hips. Avascular necrosis (AVN) of the femoral head represents a severe, underrecognized complication whose pathogenesis in AS is multifactorial—encompassing disease ...
Syeda Simrah Shah, Muhammad Ahsan, Tehreem Farooq, Mirza Daniyal Baig, Mirza Mohammad Ali Baig, Mohammed Hammad Jaber Amin   +5 more
wiley   +1 more source

SAPHO Syndrome Presenting With Severe Inflammatory Back Pain (Sacroiliitis) and Rare Retinol Associated Myopathy in an Iraqi Adolescent Male: A Case Report and Literature Review

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT SAPHO syndrome is a rare autoinflammatory disorder characterized by synovitis, acne, pustulosis, hyperostosis, and osteitis. Although musculoskeletal and dermatologic manifestations are well recognized, extra‐articular involvement remains uncommon, particularly muscular inflammation.
Farah Jaafar Mahdi, Ali Saad Al‐Shammari, Mustafa Majid Hameed, Marwah Sami Ahmed, Ibrahim Khalil, Zahraa Saeed Fahad, Ahmed Dahham Hasan, Nizar Abdulateef Jassim   +7 more
wiley   +1 more source

An Investigation of Hyperostosis Frontalis Interna in a Modern Anatomical Body Donor Population

Clinical Anatomy, Volume 39, Issue 2, Page 211-233, March 2026.
ABSTRACT This research sought to examine the prevalence and severity of hyperostosis frontalis interna (HFI) in the Chicagoland anatomical body donor population. The study further aimed to elucidate potential demographic risk factors for HFI, including sex, age at death, and structural vulnerability index (SVI), as well as any common comorbidities, as ...
Amy C. Beresheim, Amanda Hall
wiley   +1 more source

Fixed and Fluid: The Two Faces of Gender Roles—A Combined Study of Activity Patterns and Burial Practices in the European Neolithic

American Journal of Biological Anthropology, Volume 189, Issue 2, February 2026.
ABSTRACT Objectives This study investigates gender roles in the European Neolithic by analyzing activity‐related skeletal changes (ARSCs) and burial practices at two Polgár microregion sites in Hungary: Polgár‐Ferenci‐hát (5300–5070 cal. bce) and Polgár‐Csőszhalom (4800–4650 cal. bce). Materials and Methods A total of 125 well‐preserved adult skeletons
Sébastien Villotte, Tamás Szeniczey, Sacha Kacki, Alexandra Anders   +3 more
wiley   +1 more source

Emerging Role of Acitretin in Cutaneous Squamous Cell Carcinoma: From Prevention to Treatment

Dermatologic Therapy, Volume 2026, Issue 1, 2026.
Cutaneous squamous cell carcinoma (cSCC) is one of the most common cancers worldwide, with an increasing incidence that poses a significant public health challenge. Acitretin, a synthetic retinoid clinically used to treat epidermal hyperproliferative disorders, has emerged as a promising therapy for cSCC.
Fujin Zhou, Ziwei Kang, Zhenlin Li, Guorong Yan, Guolong Zhang, Suraiya Saleem   +5 more
wiley   +1 more source

A Novel MAP3K7 Variant Causing Loss of Function Identified in a Family With Cardiospondylocarpofacial Syndrome: Functional Validation and Molecular Insights

Human Mutation, Volume 2026, Issue 1, 2026.
Mitogen‐activated protein kinase kinase kinase 7 (MAP3K7), also known as transforming growth factor‐β–activated kinase 1 (TAK1), is a widely expressed kinase that plays a crucial role in various cellular processes variants in the MAP3K7 gene have been implicated in two distinct genetic disorders: frontometaphyseal dysplasia Type 2 (FMD2) and ...
Ting Zhu, Jiamin Shi, Jia Li, Tingmin Zhou, Xinru Fu, Fengzhen Xu, Chuangjie Gu, Danping Wang, Ruiting Wu, Li Liu, Jingling Shen, Dan Wang, Harleen Khatra   +12 more
wiley   +1 more source

The Concise Guide to PHARMACOLOGY 2025/26: Transporters

British Journal of Pharmacology, Volume 182, Issue S1, Page S404-S496, December 2025.
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander, Alasdair J. Gibb, Eamonn Kelly, Alistair A. Mathie, Chloe J. Peach, Emma L. Veale, Jane F. Armstrong, Elena Faccenda, Simon D. Harding, Christopher Southan, Jamie A. Davies, Laura Amarosi, Catriona M. H. Anderson, Philip M. Beart, Stefan Broer, Paul A. Dawson, Gergely Gyimesi, Bruno Hagenbuch, James R. Hammond, Jules C. Hancox, Michal Hershfinkel, Ken‐ichi Inui, Yoshikatsu Kanai, Stephan Kemp, Edmund R. S. Kunji, Gavin Stewart, Sotiria Tavoulari, David T. Thwaites, Tiziano Verri   +28 more
wiley   +1 more source