Results 31 to 40 of about 1,953,005 (139)

Spontaneous bleeding in a patient with malignant lymphoma: A case of acquired hemophilia [PDF]

, 2000
Background: Acquired hemophilia is a rare condition which can be associated with lymphoproliferative disease. Case Report: Eleven yea rs after the diagnosis of immunocytoma had been made, a 72-year-old man developed a high-titer factor VIII inhibitor. At
Brack, N., Gesierich, Wolfgang, Pohlmann, H., Munker, Reinhold, Geiersberger, U., Hartenstein, R.   +5 more
core   +1 more source

Hierarchical Superposition Framework Reveals the Complex Effects of Natural Medicine Formulas

Advanced Intelligent Systems, Volume 7, Issue 11, November 2025.
A novel hierarchical superposition pharmacological model incorporates the principle of hierarchical structures from physics to simulate the spatiotemporal dynamics of drug combinations, to elucidate the universal law underlying drug combination effects. By modeling cross‐level causal transmission and attenuation, it advances beyond traditional additive
Weifeng Liang, Dingsi Xiang, Shengli Mi, Jiajun Huang   +3 more
wiley   +1 more source

Case reports: aseptic femoral osteitis and sternocostal hyperostosis from SAPHO syndrome.

, 2005
Synovitis, acne, pustulosis, hyperostosis, and osteitis syndrome are characterized by peculiar bone lesions that commonly involve the anterior chest wall.
Franz T, Eggli S, Lehmann T
core   +1 more source

Melorheostosis: Clinical, radiological, and histopathological features with a literature review

Physiological Reports, Volume 13, Issue 21, November 2025.
Abstract Melorheostosis is a rare sclerosing bone dysplasia that can clinically and radiologically mimic common bone disorders, particularly in atypical presentations. Its heterogeneous manifestations and limited awareness among clinicians frequently contribute to diagnostic delays or misdiagnosis. We report the case of a 34‐year‐old woman with chronic
Elif Koca, Şeyhmus Kavak, Bilal Demir, Nil Comunoglu, Fatih Kantarci, Oguzhan Koca   +5 more
wiley   +1 more source

Transforming Growth Factor‐Beta Signaling in Cancer: Therapeutic Implications, Challenges, and Pathways to Progress

MedComm – Oncology, Volume 4, Issue 3, September 2025.
TGF‐β inhibition is emerging as a promising cancer therapy, yet translating laboratory success to bedside implementation has suffered significant setbacks. The associated challenges include adverse drug reactions, inadequate predictive models, and activation of alternative signaling pathways.
Faizah A. Alabi, Izuchukwu F. Okpalanwaka, Adenike Oyegbesan, Ebenezar Okoyeocha, Mariam Oladejo, Sikiru O. Imodoye   +5 more
wiley   +1 more source

Phosphatidylcholine Ameliorates Palmitic Acid‐Induced Lipotoxicity by Facilitating Endoplasmic Reticulum and Mitochondria Contacts in Intervertebral Disc Degeneration

JOR SPINE, Volume 8, Issue 2, June 2025.
The abnormal lipotoxic condition in nucleus pulposus (NP) cells from advanced‐stage intervertebral disc degeneration (IDD) was identified through untargeted LC/MS metabolomics and magnetic resonance spectroscopy. The palmitic acid accumulation resulted in endoplasmic reticulum stress, mitochondrial damage, lipid droplet accumulation, and senescence of ...
Shuangshuang Tu, Yijun Dong, Chuanfu Li, Mingxin Jiang, Liqun Duan, Wenzhi Zhang, Xi Chen   +6 more
wiley   +1 more source

Delay in Reporting Acquired Immune Deficiency Syndrome (AIDS) [PDF]

As of March 31, 1987, the U.S. Centers for Disease Control had reported 33,350 cases of acquired immune deficiency syndrome. Yet by that date, physicians had actually diagnosed 42,670 cases.
Jeffrey E. Harris
core  

Coincidence of Eagle Syndrome and Diffuse Idiopathic Skeletal Hyperostosis Presenting With Dysphagia as a Result of Compression of the Hypopharynx

, 2017
Coincidence of the Eagle syndrome and diffuse idiopathic skeletal hyperostosis can very rarely result with compression of the hypopharynx. The authors here described a very rare case of hypopharyngeal airway compression secondary to cervical osteophytes ...
MUTLU, Vahit, OĞUL, Hayri
core   +1 more source

Impact of Working From Home on the Psychological Well‐Being of 365 European Patients With Rheumatic Diseases During COVID‐19 Pandemic. Results of the REUMAVID Study

Musculoskeletal Care, Volume 23, Issue 2, June 2025.
ABSTRACT Objective To evaluate the impact of home working on the psychological well‐being of European patients with Rheumatic and Musculoskeletal Diseases (RMDs) during the COVID‐19 pandemic. Methods REUMAVID is a cross‐sectional study that collected data through an online survey in seven European countries during the COVID‐19 pandemic: Phase 1 (April ...
Marco Garrido‐Cumbrera, Helena Marzo‐Ortega, José Correa‐Fernández, Laura Christen, Victoria Navarro‐Compán   +4 more
wiley   +1 more source

Prenatal Diagnosis of Proteus Syndrome: About a Case

American Journal of Medical Genetics Part A, Volume 197, Issue 5, May 2025.
ABSTRACT Proteus syndrome (PS) is a rare disorder (< 1/1000000), marked by progressive overgrowth commonly impacting the skeleton, skin, adipose tissue, and central nervous system. Clinical criteria were established in 2019. PS arises from a somatic activating variation in the AKT1 gene.
Luana Giovannangeli, Virginie Magry, Florence Jobic, Kahia Messaoudi, Walaa Darwiche, Marianne Perriere, Alexis Billes, Ségolène Delmas Lanta, Alice Masurel, Gilles Morin, Guillaume Jedraszak   +10 more
wiley   +1 more source