Results 21 to 30 of about 1,382 (156)

SAPHO syndrome with enthesopathy [PDF]

BMJ Case Reports, 2019
Synovitis, acne, pustulosis, hyperostosis and osteitis (SAPHO) syndrome was first described as chronic recurrent multifocal osteomyelitis. Because of its rarity, a thorough description of its clinical manifestations is lacking. Herein, we describe the clinical manifestations and imaging features, especially the enthesopathy in bilateral Achilles ...
Chin-Fang Su, Yu-Chuan Shen, Hsien-Tzung Liao, Chang-Youh Tsai   +3 more
openaire   +2 more sources

Transient hypercalcemia in a patient with SAPHO syndrome

Journal of General and Family Medicine, 2022
We here report a case of SAPHO (synovitis‐acne‐pustulosis‐hyperostosis‐osteitis) syndrome with hypercalcemia. The patient was diagnosed with SAPHO syndrome at the age of 54, because he exhibited osteitis and hyperostosis around the sternoclavicular ...
Tadashi Yoshida, Mototsugu Oya
doaj   +1 more source

Synovitis, Acne, Pustulosis, Hyperostosis, and Osteitis Syndrome with Purely Osteolytic, Not Osteosclerotic, Lesions Mimicking a Malignant Tumor

Case Reports in Rheumatology, 2020
Synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome is a rare inflammatory disorder with multiple phenotypes. The syndrome has identifiable radiologic characteristics that are the most important when making a diagnosis.
Hideyuki Kinoshita, Takeshi Ishii, Hiroto Kamoda, Yoko Hagiwara, Toshinori Tsukanishi, Sumihisa Orita, Kazuhide Inage, Naoya Hirosawa, Seiji Ohtori, Tsukasa Yonemoto   +9 more
doaj   +1 more source

The SAPHO Syndrome

Seminars in Arthritis and Rheumatism, 2012
To review the epidemiology, presentation, diagnosis, treatment, pathogenesis, and genetics of the syndrome known under the acronym of SAPHO for Synovitis, Acne, Pustulosis, Hyperostosis, and Osteitis to heighten awareness of this entity.We conducted a Medline search using SAPHO syndrome, chronic recurrent multifocal osteitis/osteomyelitis, and related ...
M. T. Nguyen, A. T. Borchers, C. Selmi, S. M. Naguwa, G. Cheema, M. E. Gershwin   +5 more
openaire   +3 more sources

The dark side of SAPHO syndrome [PDF]

BMJ Case Reports, 2011
SAPHO syndrome (synovitis, acne, pustulosis, hyperostosis and osteitis) is a relatively rare entity. The therapeutic approach of patients with SAPHO syndrome has included multiple drugs with varying success and incoherence responses. The therapy is still empirical today.
Coelho Henriques, C, Sousa, M, Panarra, A, Riso, N   +3 more
openaire   +3 more sources

Successful treatment of synovitis, acne, pustulosis, hyperostosis, and osteitis and paradoxical skin lesions by hook f: a case report

Journal of International Medical Research, 2020
Synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome is a rare autoinflammatory disorder without standardized therapy. Anti-tumor necrosis factor (TNF)-α agents, which have been widely used in recent treatment of SAPHO syndrome, may ...
Xinlu Zhang, Xia Wu, Chen Li
doaj   +1 more source

Mandibular Osteitis Leading to the Diagnosis of SAPHO Syndrome

Case Reports in Radiology, 2018
Synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome is a disorder characterized by pustular skin lesions and osteoarticular lesions.
Tomohiro Kikuchi, Hiroyuki Fujii, Akifumi Fujita, Tomoko Sugiyama, Hideharu Sugimoto   +4 more
doaj   +1 more source

Serum-derived extracellular vesicles inhibit osteoclastogenesis in active-phase patients with SAPHO syndrome

Therapeutic Advances in Musculoskeletal Disease, 2021
Objective: Synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome is a rare chronic inflammatory disorder and the underlying pathogenesis is unclear.
Yanpan Gao, Yanyu Chen, Lun Wang, Chen Li, Wei Ge   +4 more
doaj   +1 more source

SAPHO syndrome with pathological fractures of vertebral bodies: a case report

BMC Musculoskeletal Disorders, 2019
Background It’s difficult to diagnose and treat synovitis-acne-pustulosis-hyperostosis-osteomyelitis (SAPHO) syndrome due to its rare and unknown pathogenesis. There is no effective treatment for SAPHO syndrome and the consequences of empirical treatment
Yalong Li, Guomin Liu, Yian Zhao, Yungang Luo, Tiancheng Lu   +4 more
doaj   +1 more source

Tumor necrosis factor inhibitors for pediatric patients with SAPHO syndrome associated with acne conglobata

Pediatric Rheumatology Online Journal, 2022
Synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome is a rare chronic inflammatory disease with osteoarticular and cutaneous involvements as its main manifestations.
Shengyan Liu, Xia Wu, Yihan Cao, Zhaohui Li, Yuchen Liu, Mingwei Ma, Chen Li   +6 more
doaj   +1 more source