Results 81 to 90 of about 14,134 (231)

Human Inborn Errors of Immunity: 2019 Update of the IUIS Phenotypical Classification. [PDF]

, 2020
Since 2013, the International Union of Immunological Societies (IUIS) expert committee (EC) on Inborn Errors of Immunity (IEI) has published an updated phenotypic classification of IEI, which accompanies and complements their genotypic classification ...
Ailal, Fatima, Al-Herz, Waleed, Bousfiha, Aziz, Casanova, Jean-Laurent, Chatila, Talal, Cunningham-Rundles, Charlotte, Etzioni, Amos, Franco, Jose Luis, Holland, Steven M, Jeddane, Leila, Klein, Christoph, Morio, Tomohiro, Ochs, Hans D, Oksenhendler, Eric, Picard, Capucine, Puck, Jennifer, Sullivan, Kathleen E, Tangye, Stuart G, Torgerson, Troy R   +18 more
core  

SAPHO Syndrome [PDF]

, 2018
SAPHO syndrome is an entity that associates musculoskeletal disorders with dermatological alterations. The most characteristic clinical manifestation of the SAPHO syndrome is pain in the anterior chest wall, due to the involvement of the sternoclavicular
Díaz, José Ángel López, Luna, Sara Alcántara, Rubio, Luis Geniz   +2 more
core   +1 more source

Vertebral lesions associated with palmoplantar pustulosis [PDF]

International Orthopaedics, 1997
Spinal lesions were reviewed in 9 patients (3 men and 6 women) who presented with palmoplantar pustulosis. Cervical lesions were found in 3 patients and lumbosacral involvement in 7. The duration of disease averaged 4.8 years. Seven patients had associated sterno-costo-clavicular hyperostotic lesions, and all showed abnormalities in blood tests which ...
H, Baba, K, Uchida, M, Wada, S, Imura, N, Kawahara, K, Tomita   +5 more
openaire   +2 more sources

Efficacy and Safety of Brodalumab, an Anti-interleukin-17 Receptor A Monoclonal Antibody, for Palmoplantar Pustulosis: 16-Week Results of a Randomized Clinical Trial

American Journal of Clinical Dermatology
Palmoplantar pustulosis (PPP), a refractory skin disease characterized by repeated eruptions of sterile pustules and vesicles on palms and/or soles, involves interleukin-17 pathway activation.
Yukari Okubo, Satomi Kobayashi, Masamoto Murakami, S. Sano, N. Kikuta, Yoshiumi Ouchi, Tadashi Terui   +6 more
semanticscholar   +1 more source

JAK Inhibitors for Treatment of SAPHO Syndrome: A Systematic Review of 72 Cases

ACR Open Rheumatology, Volume 7, Issue 10, October 2025.
Objective Synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome usually involves bones, joints, and skin. Due to a lack of known pathogenesis and clinical trials, there is no standard treatment of SAPHO syndrome. Because none of the current treatments have a high efficacy and the risk of relapse is high, new treatment options for ...
Patrick Fazeli, Saeed Bahramian, Kimia Farahmand, Hamed Ghoshouni, Yalda Farahmand, Amirali Soheili, Leyla Bagheri, Huria Memari, Aydin Feyzi, Seyed Mohammad Vahabi   +9 more
wiley   +1 more source

Effects of Cyclosporine on Palmoplantar Pustulosis and Serum Expression of IL-17, IL-23, and TNF-α

Dermatology and Therapy, 2019
Introduction This study aimed to investigate the effects of cyclosporine on palmoplantar pustulosis (PPP) and serum expression of IL-17, IL-23, and TNF-α. Methods Patients with PPP (n = 48) were recruited and treated with cyclosporine alone.
Xian-Hua Jin, Xi Chen, Yan Mou, Jian-Xin Xia   +3 more
doaj   +1 more source

Acrodermatitis continua of Hallopeau: clinical perspectives. [PDF]

, 2019
Acrodermatitis continua of Hallopeau (ACH) is a rare, sterile pustular eruption of one or more digits. The condition presents with tender pustules and underlying erythema on the tip of a digit, more frequently arising on a finger than a toe.
Beck, Kristen M, Bhutani, Tina, Liao, Wilson, Ly, Karen, Smith, Mary Patricia, Thibodeaux, Quinn   +5 more
core  

Pustulosis palmoplantar [PDF]

Revista del Centro Dermatológico Pascua, 2021
Miguel Ángel Cardona Hernández, María del Carmen Padilla Desgarennes, César Alfonso Maldonado García, José Alberto Ramos Garibay, José Pablo Laguna Meraz   +4 more
openaire   +1 more source

Bimekizumab plus topical photochemotherapy effective in palmoplantar pustulosis in a patient with hidradenitis suppurativa

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Neda Cramer, Johannes Mohr, Michael P. Schön, Rotraut Mössner   +3 more
wiley   +1 more source

Biologics and Small‐Molecule Therapies in Netherton Syndrome: A Comprehensive Review

The Journal of Dermatology, Volume 52, Issue 10, Page 1483-1493, October 2025.
ABSTRACT Netherton syndrome (NS) is a rare congenital ichthyosis caused by loss‐of‐function mutations in the SPINK5 gene, leading to defective expression of the serine protease inhibitor LEKTI. Dysregulated epidermal protease activity results in impaired skin barrier function and chronic inflammation, accompanied by complex immune profiles. NS patients
Shin Morizane, Tomoyuki Mukai, Ko Sunagawa, Ken‐ichi Hasui, Anri Morita, Hayato Nomura, Mamoru Ouchida   +6 more
wiley   +1 more source