Results 201 to 210 of about 686,190 (235)

Evolutionary Response Patterns of the Rodent TLR Genes to Climatic Factors

Ecology and Evolution, Volume 16, Issue 9, September 2026.
This study systematically investigates the associations between climatic factors and the evolutionary dynamics of Toll‐like receptor (TLR) genes across 42 rodent species. Our findings demonstrate that temperature‐related climatic variables (Annual Mean Temperature, Mean Diurnal Range, and Max Temperature of Warmest Month) may modulate the evolutionary ...
Chao Zhao, Tian Xia, Guangshuai Liu, Zhao Liu, Xinglei Ding, Shuo Dai, Honghai Zhang   +6 more
wiley   +1 more source

The plant holobiont: integrating molecular priming and ecological legacies for climate-adaptive immunity. [PDF]

Essays Biochem
Campos-Herrera R, Alvarez-Ortega S, Pastor V.   +2 more
europepmc   +1 more source

Mechanisms and Predisposing Conditions for Statin‐Induced New‐Onset Type 2 Diabetes Mellitus: A Paradox Relative to Their Pleiotropic Metabolic Effects

Endocrinology, Diabetes &Metabolism, Volume 9, Issue 5, September 2026.
The primary function of statins is to inhibit cholesterol synthesis, which contributes to their antidiabetic effects. However, the majority of the diabetic effects of statins are due to inhibition of isoprenoid synthesis. Atorvastatin, simvastatin and rosuvastatin possess the most pronounced diabetogenic properties. In contrast, lovastatin, fluvastatin,
Ali Nosrati Andevari, Mohsen Koolivand
wiley   +1 more source

Functional Analysis Identifies Multiple Effectors of Candidatus Liberibacter Asiaticus Suppressing Plant Pattern-Triggered Immunity. [PDF]

Plants (Basel)
He Z, Li H, Zhao Z, Wang D, Wu H, Bai M, Liang X, Yu JB.   +7 more
europepmc   +1 more source

The C‐Type Lectin Mincle Serves as a Pattern Recognition Receptor for the Lipid Envelope of Human Cytomegalovirus

European Journal of Immunology, Volume 56, Issue 9, September 2026.
Whether viral lipids can directly interact with pattern recognition receptors to modulate antiviral immune responses remains unclear. We show that Mincle‐dependent recognition of HCMV viral particles induces proinflammatory cytokine production in primary human macrophages.
Vladimir Bokun, Wengang Chai, Robert Buchanan, Elliot Murphy, Yan Liu, Beth Holder, Alexiane Decout   +6 more
wiley   +1 more source

Chromatin accessibility and histone landscapes define immune signal-specific transcriptional reprogramming in <i>Arabidopsis</i>. [PDF]

aBIOTECH
Yu DT, Xie SS, Duan CG.
europepmc   +1 more source

Lactiplantibacillus plantarum BF_15 Confers Protection Against Ulcerative Colitis by Orchestrating Gut Microbiota‐Barrier‐Immune Triad Homeostasis

Food Science &Nutrition, Volume 14, Issue 9, September 2026.
Lactiplantibacillus plantarum BF_15 mitigates ulcerative colitis via modulating the triad homeostasis of gut microbiota, mucosal barrier and intestinal immunity. It restores disturbed intestinal microecology by elevating the abundance of Bacteroidetes.
Na Zhang, Hongjie Liu, Dongyao Li, Chen Li, Xinyi Ge, Hongyan Kang, Miaoshu Wang, Hongtao Tian, Xiaoyan Miao   +8 more
wiley   +1 more source

ESCRT: A Cellular Nexus of Plant Immunity and Pathogen Counter-Strategies. [PDF]

Mol Plant Pathol
Sexton WK, Xiao S.
europepmc   +1 more source

Knee Osteoarthritis Therapy Targeting NLRP3 Inflammasome: Progress From Mechanism to Application

Immunity, Inflammation and Disease, Volume 14, Issue 9, September 2026.
ABSTRACT Objective This paper briefly reviews the structure, function, and activation mechanism of the NLRP3 inflammasome and its molecular role in the pathogenesis of knee osteoarthritis (KOA), and explores the potential value of traditional Chinese medicine (TCM) in treating KOA by modulating NLRP3 inflammasome activity.
Wenguang Chen, Baoxiu Yi, Zhang Wang, Cong Yu, Ziru Li, Zenan Wu, Ensi Hong   +6 more
wiley   +1 more source

Innate Immune Memory Responses in Organ Transplantation. [PDF]

Arterioscler Thromb Vasc Biol
de Jong LC, Rother N, Duivenvoorden R.
europepmc   +1 more source