Results 141 to 150 of about 256,370 (362)
Adultery and impotence as literary spectacle in the divorce debates and tracts of the long eighteenth century [PDF]
This essay will examine the origins and emergence of the crisis that engulfed the propertied classes from the late seventeenth century onwards through an analysis of the early legal debates about matrimonial separation and the later bawdy pamphlets and ...
Capern, Amanda
core
Molecular Oncology, EarlyView.Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Molecular Oncology, EarlyView.Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Homeopathy for Acute Bronchitis in Children (English Pamphlet)
, 2010 Jishnu Shankar
openalex +2 more sources
Linguistics: An African Popular Literature: A Study of Onitsha Market Pamphlets. EMMANUEL OBIECHINA [PDF]
, 1975 Richard N. Henderson
openalex +1 more source
The light within:metaphor consistency in Quaker pamphlets, 1659-2010
, 2017 Veronika Koller
semanticscholar +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source