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Normothermic Regional Perfusion Can Improve Both Utilization and Outcomes in DCD Liver, Kidney, and Pancreas Transplantation. [PDF]

Transplant Direct, 2023
Background. Normothermic regional perfusion (NRP) has gained widespread adoption in multiple European countries. The aim of this study was to examine the influence of thoracoabdominal-NRP (TA-NRP) on the utilization and outcomes of liver, kidney, and ...
Bekki Y, Croome KP, Myers B, Sasaki K, Tomiyama K.   +4 more
europepmc   +2 more sources

Pancreas Transplantation [PDF]

Journal of the Chinese Medical Association, 2009
The first successful pancreas transplantation in conjunction with a simultaneous kidney transplantation was performed in 1966 by Kelly, Lillehei and others from the University of Minnesota.
Shyr, Yi-Ming
core   +6 more sources

First World Consensus Conference on pancreas transplantation: Part II - recommendations. [PDF]

Am J Transplant, 2021
The First World Consensus Conference on Pancreas Transplantation provided 49 jury deliberations regarding the impact of pancreas transplantation on the treatment of diabetic patients, and 110 experts’ recommendations for the practice of pancreas ...
Boggi U, Vistoli F, Andres A, Arbogast HP, Badet L, Baronti W, Bartlett ST, Benedetti E, Branchereau J, Burke GW, Buron F, Caldara R, Cardillo M, Casanova D, Cipriani F, Cooper M, Cupisti A, Davide J, Drachenberg C, de Koning EJP, Ettorre GM, Fernandez Cruz L, Fridell JA, Friend PJ, Furian L, Gaber OA, Gruessner AC, Gruessner RWG, Gunton JE, Han DJ, Iacopi S, Kauffmann EF, Kaufman D, Kenmochi T, Khambalia HA, Lai Q, Langer RM, Maffi P, Marselli L, Menichetti F, Miccoli M, Mittal S, Morelon E, Napoli N, Neri F, Oberholzer J, Odorico JS, Öllinger R, Oniscu G, Orlando G, Ortenzi M, Perosa M, Perrone VG, Pleass H, Redfield RR, Ricci C, Rigotti P, Paul Robertson R, Ross LF, Rossi M, Saudek F, Scalea JR, Schenker P, Secchi A, Socci C, Sousa Silva D, Squifflet JP, Stock PG, Stratta RJ, Terrenzio C, Uva P, Watson CJE, White SA, Marchetti P, Kandaswamy R, Berney T.   +75 more
europepmc   +2 more sources

Retroperitoneal pancreas transplantation with a Roux-en-Y duodenojejunostomy for exocrine drainage [PDF]

BMC Surgery
Background Pancreatic transplantation is the only definitive surgical treatment for diabetes mellitus. Currently, most transplant centers use enteric exocrine drainage of pancreatic secretions; however, experts disagree on which part of the ...
Mogeli Sh. Khubutiya, Ilya V. Dmitriev, Nikita S. Zhuravel, Aslan G. Balkarov, Roman V. Storozhev, Yuri A. Anisimov, Alexander S. Kondrashkin, Nonna V. Shmarina   +7 more
doaj   +2 more sources

Current state of pancreas transplantation in Japan based on the nationwide registry [PDF]

Annals of Gastroenterological Surgery, 2021
In Japan, 437 pancreas transplantations (PTx) were carried out between 2000 and 2019. Clinical data for all PTx cases are registered in the Japan Pancreas Transplant Registry of the Japan Society for Pancreas and Islet Transplantation.
Yoshito Tomimaru, Hidetoshi Eguchi, Yuichiro Doki, Toshinori Ito, Takashi Kenmochi   +4 more
doaj   +2 more sources

Pancreas Transplantation [PDF]

Gut and Liver, 2010
Diabetes mellitus is generally treated with oral diabetic drugs and/or insulin. However, the morbidity and mortality associated with this condition increases over time, even in patients receiving intensive insulin treatment, and this is largely ...
Duck Jong, Han, David Er, Sutherland
doaj   +5 more sources

Pancreas transplantation: review [PDF]

Einstein (São Paulo), 2015
Vascularized pancreas transplantation is the only treatment that establishes normal glucose levels and normalizes glycosylated hemoglobin levels in type 1 diabetic patients.
R. Meirelles, P. Salvalaggio, Á. Pacheco-Silva   +2 more
semanticscholar   +7 more sources

Frailty and prognosis of patients with kidney transplantation: a meta-analysis

BMC Nephrology, 2023
Background The prevalence of frailty among candidates and recipients of kidney transplantation (KT) is well-established, yet the impact of frailty on clinical outcomes following KT remains uncertain.
Jianming Zheng, Yu Cao, Zhen Wang, Yeqi Nian, Liping Guo, Wenli Song   +5 more
doaj   +1 more source

SIRT1 regulates hepatocyte programmed cell death via GSDME - IL18 axis in human and mouse liver transplantation

Cell Death and Disease, 2023
Sirtuin 1 (SIRT1) is a histone/protein deacetylase in the cellular response to inflammatory, metabolic, and oxidative stressors. We previously reported that myeloid SIRT1 regulates the inflamed liver’s canonical pyroptosis cell death pathway.
Kentaro Kadono, Hidenobu Kojima, Siyuan Yao, Shoichi Kageyama, Kojiro Nakamura, Hirofumi Hirao, Takahiro Ito, Kenneth J. Dery, Douglas G. Farmer, Fady M. Kaldas, Xiaoling Li, Jerzy W. Kupiec-Weglinski   +11 more
doaj   +1 more source

Recipient TIM4 signaling regulates ischemia reperfusion-induced ER stress and metabolic responses in liver transplantation: from mouse-to-human

Frontiers in Transplantation, 2023
T-cell immunoglobulin and mucin (Tim)4 is expressed on APCs, including macrophages, as one of the main amplifiers in the mechanism of liver ischemia-reperfusion injury (IRI) following orthotopic liver transplantation (OLT).
Hirofumi Hirao, Shoichi Kageyama, Kojiro Nakamura, Kentaro Kadono, Hidenobu Kojima, Yao Siyuan, Douglas G. Farmer, Fady M. Kaldas, Kenneth J. Dery, Jerzy W. Kupiec-Weglinski   +9 more
doaj   +1 more source