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Pancreas Transplantation [PDF]
Gut and Liver, 2010 Diabetes mellitus is generally treated with oral diabetic drugs and/or insulin. However, the morbidity and mortality associated with this condition increases over time, even in patients receiving intensive insulin treatment, and this is largely attributable to diabetic complications or the insulin therapy itself.
Duck Jong, Han, David Er, Sutherland
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Renal Failure, 1995 Vascularized pancreas transplantation has assumed an increasing role in the treatment of diabetes mellitus. Through 1994, over 6000 pancreas transplants had been performed worldwide, with over 80% being combined pancreas-kidney transplants. Overall 1-year patient survival exceeds 90% and graft survival (complete insulin independence) exceeds 70 ...
R J, Stratta +3 more
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Journal of the Chinese Medical Association, 2009 The first successful pancreas transplantation in conjunction with a simultaneous kidney transplantation was performed in 1966 by Kelly, Lillehei and others from the University of Minnesota. In Taipei Veterans General Hospital, the first pancreas transplantation (simultaneously coupled with kidney transplantation) was successfully performed on September
Steve A, White +2 more
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Pancreas Transplantation [PDF]
The Annals of The Royal College of Surgeons of England, 2008 Over the last 5 years, there has been a resumed interest in treating diabetes by transplantation, particularly islet transplantation. However, despite advances being reported in Canada and the US, replication in the UK has been much more difficult. At present there is still only one treatment that can consistently reverse insulin independence in the ...
S A, White, D W, Manas
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Surgery (Oxford), 2014 Pancreas transplantation is now standard of care for selected patients with diabetes and end-stage renal failure or life-threatening diabetic complications. The morbidity and mortality of pancreas transplantation is higher than other transplant types, and for this reason selection criteria for both donors and recipients are more stringent.
Knight, S, Vogel, T, Friend, P
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Clinical Radiology, 2009 Cadaveric, whole pancreas transplantation has proved an effective therapy in the treatment of long-standing type 1 diabetes mellitus and is capable of achieving an insulin-independent eugyclaemic state. As a result, this procedure is being increasingly performed. However, the surgical procedure is complex and unfamiliar to many radiologists.
Chandra, J +4 more
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Pancreas transplantation: an overview [PDF]
Einstein (São Paulo), 2010 ABSTRACT Pancreas transplantation is the only treatment able to reestablish normal glucose and glycated hemoglobin levels in insulin-dependent diabetic patients without the use of exogenous insulin. The evolution of pancreas transplantation in treatment of diabetes was determined by advances in the fields of surgical technique, organ preservation and ...
David, Andre Ibrahim +4 more
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Pancreas transplantation: review [PDF]
Einstein (São Paulo), 2015 ABSTRACT Vascularized pancreas transplantation is the only treatment that establishes normal glucose levels and normalizes glycosylated hemoglobin levels in type 1 diabetic patients. The first vascularized pancreas transplant was performed by William Kelly and Richard Lillehei, to treat a type 1 diabetes patient, in December 1966.
Meirelles Júnior, Roberto Ferreira +2 more
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Pancreas preservation for pancreas and islet transplantation [PDF]
Current Opinion in Organ Transplantation, 2008 To summarize advances and limitations in pancreas procurement and preservation for pancreas and islet transplantation, and review advances in islet protection and preservation.Pancreases procured after cardiac death, with in-situ regional organ cooling, have been successfully used for islet transplantation. Colloid-free Celsior and histidine-tryptophan-
James V. Harmon +3 more
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Biomarkers in pancreas transplant [PDF]
Current Opinion in Organ Transplantation, 2016 The review analyzes the current biomarkers used in monitoring pancreas transplant, from the simple and time-tested, to more sophisticated, including markers of allo- and autoimmunity, that are likely to play a larger role in future studies.Evaluation of alloimmunity includes serum levels of donor-specific antibody, and, ultimately, pancreas transplant ...
Alberto Pugliese +3 more
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