Results 1 to 10 of about 102,858 (188)

Retroperitoneal pancreas transplantation with a Roux-en-Y duodenojejunostomy for exocrine drainage [PDF]

BMC Surgery
Background Pancreatic transplantation is the only definitive surgical treatment for diabetes mellitus. Currently, most transplant centers use enteric exocrine drainage of pancreatic secretions; however, experts disagree on which part of the ...
Mogeli Sh. Khubutiya, Ilya V. Dmitriev, Nikita S. Zhuravel, Aslan G. Balkarov, Roman V. Storozhev, Yuri A. Anisimov, Alexander S. Kondrashkin, Nonna V. Shmarina   +7 more
doaj   +2 more sources

Pancreas Transplantation [PDF]

Gut and Liver, 2010
Diabetes mellitus is generally treated with oral diabetic drugs and/or insulin. However, the morbidity and mortality associated with this condition increases over time, even in patients receiving intensive insulin treatment, and this is largely ...
Duck Jong, Han, David Er, Sutherland
doaj   +5 more sources

Pancreas Transplantation [PDF]

The Annals of The Royal College of Surgeons of England, 2008
Over the last 5 years, there has been a resumed interest in treating diabetes by transplantation, particularly islet transplantation. However, despite advances being reported in Canada and the US, replication in the UK has been much more difficult. At present there is still only one treatment that can consistently reverse insulin independence in the ...
S A, White, D W, Manas
openaire   +3 more sources

Frailty and prognosis of patients with kidney transplantation: a meta-analysis

BMC Nephrology, 2023
Background The prevalence of frailty among candidates and recipients of kidney transplantation (KT) is well-established, yet the impact of frailty on clinical outcomes following KT remains uncertain.
Jianming Zheng, Yu Cao, Zhen Wang, Yeqi Nian, Liping Guo, Wenli Song   +5 more
doaj   +1 more source

SIRT1 regulates hepatocyte programmed cell death via GSDME - IL18 axis in human and mouse liver transplantation

Cell Death and Disease, 2023
Sirtuin 1 (SIRT1) is a histone/protein deacetylase in the cellular response to inflammatory, metabolic, and oxidative stressors. We previously reported that myeloid SIRT1 regulates the inflamed liver’s canonical pyroptosis cell death pathway.
Kentaro Kadono, Hidenobu Kojima, Siyuan Yao, Shoichi Kageyama, Kojiro Nakamura, Hirofumi Hirao, Takahiro Ito, Kenneth J. Dery, Douglas G. Farmer, Fady M. Kaldas, Xiaoling Li, Jerzy W. Kupiec-Weglinski   +11 more
doaj   +1 more source

Current state of pancreas transplantation in Japan based on the nationwide registry

Annals of Gastroenterological Surgery, 2021
In Japan, 437 pancreas transplantations (PTx) were carried out between 2000 and 2019. Clinical data for all PTx cases are registered in the Japan Pancreas Transplant Registry of the Japan Society for Pancreas and Islet Transplantation.
Yoshito Tomimaru, Hidetoshi Eguchi, Yuichiro Doki, Toshinori Ito, Takashi Kenmochi   +4 more
doaj   +1 more source

Kidney Donation after circulatory death: The Veneto Region experience in Italy

Transplantation Reports, 2023
Donation after circulatory death (DCD) is a promising strategy for increasing organ supply worldwide. The Italian current legislative framework has represented a major barrier to the implementation of such program, given the 20-minute no-touch period ...
C. Di Bella, G. Feltrin, C. Silvestre, F. Tuci, M. Di Bello, E. Rosso, P. Rigotti, L. Furian   +7 more
doaj   +1 more source

Comparison of long-term outcomes in simultaneous pancreas-kidney transplant versus simultaneous deceased donor pancreas and living donor kidney transplant

Scientific Reports, 2023
Simultaneous deceased donor pancreas and living donor kidney transplant (SPLK) has certain advantages over conventional simultaneous pancreas-kidney transplant (SPK) and may be beneficial for overcoming the paucity of organs needed for diabetic patients ...
Jin-Myung Kim, Youngmin Ko, Minha Choi, Hye Eun Kwon, Jae Jun Lee, Joo Hee Jung, Hyunwook Kwon, Young Hoon Kim, Sung Shin   +8 more
doaj   +1 more source

Recipient TIM4 signaling regulates ischemia reperfusion-induced ER stress and metabolic responses in liver transplantation: from mouse-to-human

Frontiers in Transplantation, 2023
T-cell immunoglobulin and mucin (Tim)4 is expressed on APCs, including macrophages, as one of the main amplifiers in the mechanism of liver ischemia-reperfusion injury (IRI) following orthotopic liver transplantation (OLT).
Hirofumi Hirao, Shoichi Kageyama, Kojiro Nakamura, Kentaro Kadono, Hidenobu Kojima, Yao Siyuan, Douglas G. Farmer, Fady M. Kaldas, Kenneth J. Dery, Jerzy W. Kupiec-Weglinski   +9 more
doaj   +1 more source

Using Laser Speckle Contrast Imaging to Quantify Perfusion Quality in Kidney and Pancreas Grafts on Vascular Reperfusion: A Proof-of-Principle Study

Transplantation Direct, 2023
Introduction. The accuracy of intraoperative graft perfusion assessment still remains subjective, with doppler examination being the only objective adjunct.
Jeevan Prakash Gopal, MS, MRCS, Osborne Vaz, MS, FRCS, Rebecca Varley, MSc, MRCS, Harry Spiers, BSc, MRCS, Matthew A. Goldsworthy, MRes, MRCS, Vishwanath Siddagangaiah, MS, MRCS, Brian Lock, MBA, Videha Sharma, PhD, MRCS, Angela Summers, BSc, PhD, Zia Moinuddin, PhD, FRCS, David van Dellen, MD, FRCS, Titus Augustine, MS, FRCS   +11 more
doaj   +1 more source