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Pancreas Transplantation [PDF]

open access: yesGut and Liver, 2010
Diabetes mellitus is generally treated with oral diabetic drugs and/or insulin. However, the morbidity and mortality associated with this condition increases over time, even in patients receiving intensive insulin treatment, and this is largely ...
Duck Jong, Han, David Er, Sutherland
doaj   +6 more sources

Pancreas transplantation

open access: yesLancet, The, 2009
The first successful pancreas transplantation in conjunction with a simultaneous kidney transplantation was performed in 1966 by Kelly, Lillehei and others from the University of Minnesota. In Taipei Veterans General Hospital, the first pancreas transplantation (simultaneously coupled with kidney transplantation) was successfully performed on September
Steve A White   +2 more
exaly   +6 more sources

Retroperitoneal pancreas transplantation with a Roux-en-Y duodenojejunostomy for exocrine drainage [PDF]

open access: yesBMC Surgery
Background Pancreatic transplantation is the only definitive surgical treatment for diabetes mellitus. Currently, most transplant centers use enteric exocrine drainage of pancreatic secretions; however, experts disagree on which part of the ...
Mogeli Sh. Khubutiya   +7 more
doaj   +2 more sources

Progression of diabetic nephropathy after successful pancreas transplantation alone: a case report

open access: yesKorean Journal of Transplantation, 2019
Pancreas transplantation is the only method that can nearly cure insulin-dependent diabetes mellitus. However, the effect of pancreas transplantation on patients with diabetic nephropathy has recently been considered controversial.
Yoonhong Kim   +7 more
doaj   +2 more sources

Frailty and prognosis of patients with kidney transplantation: a meta-analysis

open access: yesBMC Nephrology, 2023
Background The prevalence of frailty among candidates and recipients of kidney transplantation (KT) is well-established, yet the impact of frailty on clinical outcomes following KT remains uncertain.
Jianming Zheng   +5 more
doaj   +1 more source

SIRT1 regulates hepatocyte programmed cell death via GSDME - IL18 axis in human and mouse liver transplantation

open access: yesCell Death and Disease, 2023
Sirtuin 1 (SIRT1) is a histone/protein deacetylase in the cellular response to inflammatory, metabolic, and oxidative stressors. We previously reported that myeloid SIRT1 regulates the inflamed liver’s canonical pyroptosis cell death pathway.
Kentaro Kadono   +11 more
doaj   +1 more source

Current state of pancreas transplantation in Japan based on the nationwide registry

open access: yesAnnals of Gastroenterological Surgery, 2021
In Japan, 437 pancreas transplantations (PTx) were carried out between 2000 and 2019. Clinical data for all PTx cases are registered in the Japan Pancreas Transplant Registry of the Japan Society for Pancreas and Islet Transplantation.
Yoshito Tomimaru   +4 more
doaj   +1 more source

Kidney Donation after circulatory death: The Veneto Region experience in Italy

open access: yesTransplantation Reports, 2023
Donation after circulatory death (DCD) is a promising strategy for increasing organ supply worldwide. The Italian current legislative framework has represented a major barrier to the implementation of such program, given the 20-minute no-touch period ...
C. Di Bella   +7 more
doaj   +1 more source

Comparison of long-term outcomes in simultaneous pancreas-kidney transplant versus simultaneous deceased donor pancreas and living donor kidney transplant

open access: yesScientific Reports, 2023
Simultaneous deceased donor pancreas and living donor kidney transplant (SPLK) has certain advantages over conventional simultaneous pancreas-kidney transplant (SPK) and may be beneficial for overcoming the paucity of organs needed for diabetic patients ...
Jin-Myung Kim   +8 more
doaj   +1 more source

Recipient TIM4 signaling regulates ischemia reperfusion-induced ER stress and metabolic responses in liver transplantation: from mouse-to-human

open access: yesFrontiers in Transplantation, 2023
T-cell immunoglobulin and mucin (Tim)4 is expressed on APCs, including macrophages, as one of the main amplifiers in the mechanism of liver ischemia-reperfusion injury (IRI) following orthotopic liver transplantation (OLT).
Hirofumi Hirao   +9 more
doaj   +1 more source

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