Results 131 to 140 of about 1,318,825 (382)

Increased Risk of Squamous-Cell Carcinoma in Simultaneous Pancreas Kidney Transplant Recipients Compared with Kidney Transplant Recipients [PDF]

, 2009
Hermina C. Wisgerhof, Paul J. M. van der Boog, Johan W. de Fijter, Ron Wolterbeek, Geert W. Haasnoot, Frans H.J. Claas, Rein Willemze, Jan Nico Bouwes Bavinck   +7 more
openalex   +1 more source

Successful treatment of central nervous system lymphoproliferative disorder in a kidney-pancreas and stem cell transplanted patient using intrathecal rituximab [PDF]

, 2021
Μaria Anastasiou, Anne‐Claire Mamez, Stavroula Masouridi, María Isabel Vargas, Karine Hadaya, Kristóf Égervári, Yves Chalandon   +6 more
openalex   +1 more source

Targeting the Notch1‐YY1‐ICAM1 Signaling Axis Enhances the Efficacy of Immunotherapy in HCC by Activating CD8+ T‐Cell‐Driven Cancer Cell Pyroptosis

Advanced Science, EarlyView.
In hepatocellular carcinoma (HCC), aberrantly activated Notch1 signaling induces its target gene YY1, which impairs immunotherapy efficacy by suppressing tumor cell‐ICAM1‐driven T cell activation and the mediated pyroptosis of T cells against tumor cells.
Ke Zhu, Fa‐Peng Zhang, Chao Qin, Zhi‐Xiao Song, Cai‐Ni Yang, Shu‐Sheng Lin, Xian‐Huan Yu, Wen‐Rui Wu, Chao‐Qun Liu, Chao Liu, Lei‐Bo Xu   +10 more
wiley   +1 more source

TP53 R249S mutation in hepatic organoids captures the predisposing cancer risk

Hepatology, EarlyView., 2022
The systematic approach in elucidating the gain‐of‐function (GOF) roles of TP53 mutations in early liver carcinogenesis. Unique downstream targets of TP53 L3 mutations were identified from chormatin immunoprecipitation sequencing in HCC cell lines, followed by a series of validation assays to substantiate the exclusive transcriptional regulations ...
Yin Kau Lam, Jianqing Yu, Hao Huang, Xiaofan Ding, Alissa M. Wong, Howard H. Leung, Anthony W. Chan, Kelvin K. Ng, Mingjing Xu, Xin Wang, Nathalie Wong   +10 more
wiley   +1 more source

Pregnancy after orthotopic liver transplantation: a comprehensive review

Frontiers in Transplantation
BackgroundMedical innovations and advancements, such as orthotopic liver transplantation (OLT) allow thousands of patients worldwide to live comfortably, despite previously life-threatening conditions.
Daria A. Stelmach, Daria A. Stelmach, Kenneth J. Dery, Zoulikha Jabiry-Zieniewicz, Jerzy W. Kupiec-Weglinski   +4 more
doaj   +1 more source

The KDM6B/SLC10A2 Axis Suppresses MDSCs Recruitment via ERK/AP‐1 Signaling in Colorectal Cancer

Advanced Science, EarlyView.
In wild‐type intestinal epithelial cells, KDM6B demethylates SLC10A2 to promote its expression, after which SLC10A2 suppresses ERK phosphorylation, inhibiting AP‐1 (Fos/Jun) transcription and chemokine production. In KDM6B‐deficient intestinal epithelial cells, SLC10A2 methylation increases, and its expression decreases.
Zhibo Hu, Jing Xun, Bin Liu, Xiaolin Jiang, Yingdi Han, Huichao Yang, Qi Gao, Ruifang Gao, Aimin Zhang, Xueliang Wu, Dapeng Zhang, Dihua Li, Tian Li, Shimin Yang, Ximo Wang, Xiangyang Yu, Qi Zhang   +16 more
wiley   +1 more source

OUTCOME OF SECOND PANCREAS TRANSPLANTATION IN PATIENTS WITH PREVIOUS SIMULTANEOUS KIDNEY AND PANCREAS TRANSPLANTATION COMPARED TO PATIENTS WITH PREVIOUS KIDNEY ALONE TRANSPLANTATION [PDF]

Acta Medica Iranica, 2007
"nThere had been few if any study for second pancreas transplant outcome and consequences in patients with simultaneous kidney pancreas transplant after failure of the first pancreas allograft.
R. Hekmat, S. Gareh, E. Morelon, N. Lefrancois L. Badet   +3 more
doaj   +2 more sources

Pancreas transplantation

Nephrology Dialysis Transplantation, 2020
Andrew, Sutherland, Lorna, Marson
openaire   +2 more sources

Integrative Omics Defines Metabolic Biomarkers and Genetic Regulatory Mechanisms of Mortality Risk

Advanced Science, EarlyView.
Understanding mortality mechanisms remains a fundamental challenge. Through multi‐omics analysis of a three‐generation chicken model, are identified 45,585 mQTLs and establish a 16‐metabolite predictor of mortality. An inflammation‐growth trade‐off and evolutionarily conserved pathways involving butyrate–microbiota interactions and L‐cysteine's dual ...
Peihao Liu, Bingxing An, Jumei Zheng, Qiao Wang, Zhirui Yang, Zhengda Li, Dawei Liu, Fan Ying, Jie Wen, Lingzhao Fang, Guiping Zhao   +10 more
wiley   +1 more source

European Society for Organ Transplantation (ESOT) Consensus Statement on the Role of Pancreas Machine Perfusion to Increase the Donor Pool for Beta Cell Replacement Therapy [PDF]

, 2023
Joana Ferrer, Benoît Mesnard, Franka Messner, Jason B. Doppenberg, Cinthia B. Drachenberg, Marten A. Engelse, Paul Johnson, Henri G. D. Leuvenink, Gabriel C. Oniscu, Vassilios Papalois, Rutger J. Ploeg, Trevor Reichman, William E. Scott, Fabio Vistoli, Thierry Berney, Daniel Jacobs‐Tulleneers‐Thevissen, Nicos Kessaris, Annemarie Weißenbacher, Ann Etohan Ogbemudia, Steve White, Julien Branchereau   +20 more
openalex   +1 more source