Results 141 to 150 of about 48,639 (314)

Enhancing antitumor immunity through the combination of cholesterolized TLR7 agonist liposomes and radiotherapy: a role for IL‐1β and the inflammasome pathway

open access: yesCancer Communications, EarlyView.
Abstract Background Radiotherapy (RT) is a key treatment modality in cancer therapy, utilizing high‐energy radiation to directly kill tumor cells. Recent research has increasingly highlighted RT's potential to indirectly enhance antitumor immunity. However, this immune activation alone often fails to generate sustained systemic antitumor responses.
Xuejiao Han   +11 more
wiley   +1 more source

Pancreas transplantation

open access: yesNephrology Dialysis Transplantation, 2020
Andrew, Sutherland, Lorna, Marson
openaire   +2 more sources

Outcomes of pancreas transplantation in patients with underlying inflammatory bowel disease: a retrospective case series. [PDF]

open access: yesAnn Med Surg (Lond), 2023
Ray S   +9 more
europepmc   +1 more source

FLOT1 Is a Novel Serum Biomarker of Ovarian Cancer Targeted by N6‐methyladenosine Modification Inhibition

open access: yesCell Biology International, EarlyView.
ABSTRACT Ovarian cancer (OC) is a deadly disease and lacks a precise marker for diagnosis worldwide. Our previous work has shown the overexpression of flotillin‐1 (FLOT1) in OC tissue. To improve diagnostic sensitivity and accuracy, we evaluated the serum level of FLOT1 in OC patients and found that the serum concentration of FLOT1 as well as CA125 was
Bin Guan   +7 more
wiley   +1 more source

Beyond prediction: Off‐target uses of artificial intelligence‐based predictive analytics in a learning health system

open access: yesLearning Health Systems, Volume 7, Issue 1, January 2023., 2023
Abstract Introduction Artificial‐intelligence (AI)‐based predictive analytics provide new opportunities to leverage rich sources of continuous data to improve patient care through early warning of the risk of clinical deterioration and improved situational awareness.Part of the success of predictive analytic implementation relies on integration of the ...
Jessica Keim‐Malpass   +4 more
wiley   +1 more source

Evaluating Global and Temporal Trends in Pancreas and Islet Cell Transplantation: Public Awareness and Engagement

open access: yesClinics and Practice
Background: Pancreas transplantation is a crucial surgical intervention for managing diabetes, but it faces challenges such as its invasive nature, stringent patient selection criteria, organ scarcity, and centralized expertise.
Oscar A. Garcia Valencia   +9 more
doaj   +1 more source

β‐Glucuronidase‐Responsive Albumin‐Binding Prodrug of Colchicine‐Site Binders for Selective Cancer Therapy

open access: yesChemMedChem, EarlyView.
This study presents a β‐glucuronidase‐responsive albumin‐binding prodrug enabling the selective release within the tumor microenvironment of an Isocombretastatin A‐4 analog. In triple‐negative breast cancer (TNBC) mouse models, this prodrug demonstrated significant tumor growth inhibition, highlighting potential for enhanced therapeutic selectivity and
Alexandra Bordes   +6 more
wiley   +1 more source

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