Results 141 to 150 of about 105,778 (287)

Extracellular Vesicles in Autoimmune Diseases: From Diagnostic Biomarkers to Engineered Therapeutics

Advanced Science, EarlyView.
This review provides a systematic comparison of extracellular vesicles (EVs) from both mammalian and plant sources in the context of autoimmune diseases. It highlights their emerging roles as precision biomarkers and engineered therapeutic platforms.
Yufei Wu, Huiyuan Ma, Tinghui Zhu, Shuwei Huang, Manxi Lu, Qiong Wang, Zai‐Long Chi   +6 more
wiley   +1 more source

TP53 R249S mutation in hepatic organoids captures the predisposing cancer risk

Hepatology, EarlyView., 2022
The systematic approach in elucidating the gain‐of‐function (GOF) roles of TP53 mutations in early liver carcinogenesis. Unique downstream targets of TP53 L3 mutations were identified from chormatin immunoprecipitation sequencing in HCC cell lines, followed by a series of validation assays to substantiate the exclusive transcriptional regulations ...
Yin Kau Lam, Jianqing Yu, Hao Huang, Xiaofan Ding, Alissa M. Wong, Howard H. Leung, Anthony W. Chan, Kelvin K. Ng, Mingjing Xu, Xin Wang, Nathalie Wong   +10 more
wiley   +1 more source

Errate: Modification of Venous Outflow to Avoid Thrombotic Graft Failure in Pancreas Transplantation. [PDF]

Ann Transplant, 2023
Ryu JH, Shim JR, Lee TB, Yang K, Kim T, Kim SR, Choi B.   +6 more
europepmc   +1 more source

Segmental pancreatic allotransplantation in type I diabetics [PDF]

, 1984
Burg, D., Castro, L. A., Illner, Wolf-Dieter, Kampik, Anselm, Land, Walter, Landgraf, R., Landgraf-Leurs, M. M. C., Witzgall, H.   +7 more
core   +1 more source

Modulation of Network Plasticity Opens Novel Therapeutic Possibilities in Cancer, Diabetes, and Neurodegeneration

Advanced Science, EarlyView.
Plasticity changes of molecular networks form a cellular learning process. Signaling network plasticity promotes cancer, metastasis, and drug resistance development. 55 plasticity‐related cancer drug targets are listed (20 having already approved drugs, 9 investigational drugs, and 26 being drug target candidates).
Márk Kerestély, István Narozsny, Levente Szarka, Daniel V. Veres, Peter Csermely, Dávid Keresztes   +5 more
wiley   +1 more source

Pancreas transplantation

Zdravniški Vestnik, 2015
The transplantation of the pancreas replaces endocrine function of the pancreas, establish normoglycemia, prevents the progression of chronic diabetic complications and prolongs patients life.
Damjan Kovač, Aleš Tomažič, Marjeta Tomažič   +2 more
doaj  

Impact of Perioperative Prophylaxis With Enterococcus Activity on Risk of Surgical-Site Infection After Pancreas Transplantation. [PDF]

Transplant Direct, 2023
Yetmar ZA, McCord M, Lahr BD, Kudva YC, Seville MT, Bosch W, Lemke A, Katariya NN, Reddy KS, Perry DK, Huskey JL, Jarmi T, Kukla A, Dean PG, Bernard SA, Beam E.   +15 more
europepmc   +1 more source

Mitochondrial Transplantation as a Therapeutic Strategy for Inherited Mitochondrial Diseases

Advanced Science, EarlyView.
Mitochondrial transplantation (MTx) offers a promising therapeutic avenue for mitochondrial diseases. This review comprehensively evaluates MTx, differentiating its feasibility for mtDNA‐ and nDNA‐based disorders. It examines its potential for genetic correction, alongside inherent limitations, technical challenges, and crucial ethical considerations ...
Parmeshar Singh, Amir Tahavvori, Cyrus E. Kuschner, Blanca B. Espin, Jacob Kazmi, Sofhia V. Ramos, Tai Yin, Kei Hayashida, Kanako Ito‐Hagiwara, Yusuke Endo, Keitaro Yoshioka, Jun Hagiwara, Avijot Sohi, Alisha Oropallo, Ghania Haddad, Timmy Li, Lance B. Becker, Junhwan Kim   +17 more
wiley   +1 more source

A Prospective Study of the Effect of Gastroduodenal Artery Reconstruction on Duodenal Oxygenation and Enzyme Content After Pancreas Transplantation. [PDF]

World J Surg, 2023
Offerni JCM, Ai Li E, Rasmussen A, Xie WY, Levine MA, Murkin J, McAlister VC, Luke PP, Sener A.   +8 more
europepmc   +1 more source

Preoperative Aortic Calcification Volume Predicts Postoperative Complications in Nonpancreatic Cancer Patients Undergoing Pancreaticoduodenectomy

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Background/Objectives Postoperative complications following pancreaticoduodenectomy (PD) remain high, particularly in patients with soft pancreatic texture. Abdominal aortic calcification volume (AACV), a surrogate marker of systemic arteriosclerosis, has been associated with increased surgical risk in lower gastrointestinal procedures ...
Masaki Horiuchi, Kentaro Miyake, Kota Sahara, Jun Yamamoto, Yutaro Kikuchi, Yasuhiro Yabushita, Yu Sawada, Yuki Homma, Ryusei Matsuyama, Itaru Endo   +9 more
wiley   +1 more source