Results 101 to 110 of about 40,592 (260)

Contrasting Effects of Chronic Glucokinase Activation and Inhibition on Pancreatic Beta‐Cell Function

The FASEB Journal, Volume 40, Issue 7, 15 April 2026.
In the non‐diabetic beta‐cell (top left) activation of glucokinase (bottom left) leads to inhibition of mitochondrial metabolism and thereby impairs insulin secretion. The effect is similar to that of chronic hyperglycaemia as seen in the diabetic beta‐cell (top right).
Matthew Lloyd, Natascia Vedovato, Samuel J. Mullan, Alice Elphick, Aerin J. Dumenil, Chantal Rufer, Alexandra C. Title, Burcak Yesildag, Elizabeth Haythorne, Frances M. Ashcroft   +9 more
wiley   +1 more source

Pancreatic Neuroendocrine Tumor Leading to a Diagnosis of Multiple Endocrine Neoplasia Type 1

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Pancreatic neuroendocrine neoplasms are rare but occasionally encountered. They are generally highly vascularized solid tumors, often round in shape with clear boundaries, defined contours, and a homogeneous internal structure. However, they can also present with atypical features, such as cystic degeneration, hemorrhage, calcification, and ...
Noriyuki Hirakawa, Katsuya Kitamura, Kei Yamamoto, Kenichi Tadokoro, Yasunosuke Akita, Jun Uemura, Fumito Yamanishi, Masakazu Abe, Munehide Nakatsugawa, Takao Itoi   +9 more
wiley   +1 more source

Early postoperative drain fluid amylase in risk-stratified patients promotes tailored post-pancreatectomy drain management and potential for accelerated discharge.

Surgery, 2019
BACKGROUND First postoperative day drain fluid amylase (DFA1)
T. Newhook, E. Vega, T. Vreeland, L. Prakash, W. Dewhurst, M. Bruno, Michael P. Kim, N. Ikoma, J. Vauthey, M. Katz, Jeffrey E. Lee, C. Tzeng   +11 more
semanticscholar   +1 more source

Efficacy and Safety of a 6‐Month Placement of a Fully Covered Self‐Expanding Metal Stent for Refractory or Recurrent Hepaticojejunostomy Anastomotic Stricture via Balloon Enteroscopy‐Assisted Endoscopic Retrograde Cholangiopancreatography

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Objectives Balloon enteroscopy‐assisted endoscopic retrograde cholangiopancreatography (BE‐assisted ERCP) is performed for hepaticojejunostomy anastomotic stricture (HJAS) after biliary‐enteric anastomosis. Although endoscopic balloon dilation (EBD) and plastic stent (PS) placement are commonly performed, they result in high recurrence rates ...
Taro Hanaoka, Kosuke Okuwaki, Masafumi Watanabe, Tomohisa Iwai, Kai Adachi, Akihiro Tamaki, Junro Ishizaki, Yusaku Manabe, Masayoshi Tadehara, Rikiya Hasegawa, Takaaki Matsumoto, Hiroshi Imaizumi, Mitsuhiro Kida, Chika Kusano   +13 more
wiley   +1 more source

Single-center experience description of surgical management of diffuse congenital hyperinsulinism in a pediatric non-current cohort

Frontiers in Endocrinology
IntroductionIn this study, we describe surgical indications, procedure selection, and postoperative outcomes in Chinese children with diffuse congenital hyperinsulinism (DCHI).
Xiaoxiang Li, Xiaoxiang Li, Congli Chen, Congli Chen, Yangmingyue Ji, Yuxi Wang, Yanmei Sang   +6 more
doaj   +1 more source

Comparison of Transoral Robotic Surgery and Endoscopic Laryngopharyngeal Surgery for Hypopharyngeal and Supraglottic Laryngeal Cancers

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Objectives We aimed to compare intraoperative and postoperative outcomes, technical advantages, and limitations of transoral robotic surgery (TORS) using the Da Vinci Xi robotic system and endoscopic laryngopharyngeal surgery (ELPS) for hypopharyngeal and supraglottic laryngeal cancers.
Tsutomu Ueda, Takayuki Taruya, Yuji Urabe, Minoru Hattori, Nobuyuki Chikuie, Yuki Sato, Takayoshi Hattori, Hiroaki Tahara, Takao Hamamoto, Takashi Ishino, Sachio Takeno   +10 more
wiley   +1 more source

A Collateral Venous Pathway in Omental Arch of Barkow After Spleen Preserving Distal Pancreatectomy

ANZ Journal of Surgery, EarlyView.
Cartanese Carmine, Scaramuzzi Matteo, De Luca Raffaele, Mastrandrea Giovanni, Sollitto Mario   +4 more
wiley   +1 more source

Endoscopic Step‐up Approach for Walled‐off Necrosis After Acute Pancreatitis

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT This review outlines current interventional strategies for treating symptomatic walled‐off necrosis (WON) after necrotizing pancreatitis. Mortality from acute pancreatitis has improved, but late mortality, particularly from infected necrosis, remains a challenge. WON requires invasive treatment in cases of infection or symptoms.
Shuntaro Mukai, Atsushi Sofuni, Takayoshi Tsuchiya, Reina Tanaka, Ryosuke Tonozuka, Yukitoshi Matsunami, Kazumasa Nagai, Hiroyuki Kojima, Hirohito Minami, Noriyuki Hirakawa, Kyoko Asano, Kento Shionoya, Kazuki Hama, Takao Itoi   +13 more
wiley   +1 more source

Splenic preservation versus splenectomy in laparoscopic distal pancreatectomy: a propensity score-matched study

Surgical Endoscopy, 2019
Background The laparoscopic approach in distal pancreatectomy is associated with higher rates of splenic preservation compared to open surgery. Although favorable postoperative short-term outcomes have been reported in open spleen-preserving distal ...
A. Moekotte, S. Lof, S. White, R. Marudanayagam, B. Al-Sarireh, S. Rahman, Z. Soonawalla, M. Deakin, S. Aroori, B. Ammori, D. Gomez, G. Marangoni, M. Abu Hilal   +12 more
semanticscholar   +1 more source

Adverse Events of Single Balloon Enteroscopy‐assisted Endoscopic Retrograde Cholangiopancreatography in the Elderly: A Propensity Score Matching Analysis

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Background Sedation for conventional endoscopic retrograde cholangiopancreatography (ERCP) has been reported to be safe even for elderly patients. However, the safety of sedation for balloon enteroscopy‐assisted ERCP (BE‐ERCP) has not been well‐studied in the elderly.
Hiroki Nakagawa, Tsuyoshi Takeda, Takeshi Okamoto, Takafumi Mie, Takaaki Furukawa, Takashi Sasaki, Masato Ozaka, Takahisa Matsuda, Yoshinori Igarashi, Naoki Sasahira   +9 more
wiley   +1 more source