Results 101 to 110 of about 641,720 (354)

Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients

open access: yesMolecular Oncology, EarlyView.
We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić   +31 more
wiley   +1 more source

Applications of single-cell sequencing in cancer research: progress and perspectives

open access: yesJournal of Hematology & Oncology, 2021
Single-cell sequencing, including genomics, transcriptomics, epigenomics, proteomics and metabolomics sequencing, is a powerful tool to decipher the cellular and molecular landscape at a single-cell resolution, unlike bulk sequencing, which provides ...
Yalan Lei   +7 more
doaj   +1 more source

Optical detection of fractal dimensions of MUC13 stained pancreatic tissues for cancer diagnostics [PDF]

open access: yesarXiv, 2018
Transmission intensity of a thin tissue sample produce intensity distribution that is proportional to the refractive index pattern in the thin slice, in turn reflects mass density pattern, and using the intensity pattern, fractal dimension can be calculated. In this paper, we report fractal dimension analyses of MUC13 stained pancreatic cancer tissues.
arxiv  

A Novel and Efficient Tumor Detection Framework for Pancreatic Cancer via CT Images [PDF]

open access: yesarXiv, 2020
As Deep Convolutional Neural Networks (DCNNs) have shown robust performance and results in medical image analysis, a number of deep-learning-based tumor detection methods were developed in recent years. Nowadays, the automatic detection of pancreatic tumors using contrast-enhanced Computed Tomography (CT) is widely applied for the diagnosis and staging
arxiv  

SCPMan: Shape Context and Prior Constrained Multi-scale Attention Network for Pancreatic Segmentation [PDF]

open access: yesarXiv, 2023
Due to the poor prognosis of Pancreatic cancer, accurate early detection and segmentation are critical for improving treatment outcomes. However, pancreatic segmentation is challenged by blurred boundaries, high shape variability, and class imbalance.
arxiv  

The olive biophenols oleuropein and hydroxytyrosol selectively reduce proliferation, influence the cell cycle, and induce apoptosis in pancreatic cancer cells [PDF]

open access: yes, 2018
Current chemotherapy drugs for pancreatic cancer only offer an increase in survival of up to six months. Additionally, they are highly toxic to normal tissues, drastically affecting the quality of life of patients. Therefore, the search for novel agents,
Bond, Danielle R.   +6 more
core   +2 more sources

Impact of molecular diagnostics and targeted cancer therapy on patient outcomes (MODIFY): a retrospective study of the implementation of precision oncology

open access: yesMolecular Oncology, EarlyView.
The authors conducted a retrospective study of 94 patients with advanced cancer who underwent next‐generation sequencing (NGS) gene panel analysis and received targeted treatments when applicable. Results further support evidence indicating that molecular profiling provides clinical benefit.
Michaël Dang   +3 more
wiley   +1 more source

Pancreatic Cancer [PDF]

open access: yesGastroenterology Research and Practice, 2015
Niccola Funel   +3 more
openaire   +6 more sources

Laparoscopic pancreaticoduodenectomy: are the best times coming?

open access: yesWorld Journal of Surgical Oncology, 2019
Background The introduction of laparoscopic technology has greatly promoted the development of surgery, and the trend of minimally invasive surgery is becoming more and more obvious.
Mengqi Liu   +9 more
doaj   +1 more source

Formal Modeling and Analysis of Pancreatic Cancer Microenvironment [PDF]

open access: yesarXiv, 2016
The focus of pancreatic cancer research has been shifted from pancreatic cancer cells towards their microenvironment, involving pancreatic stellate cells that interact with cancer cells and influence tumor progression. To quantitatively understand the pancreatic cancer microenvironment, we construct a computational model for intracellular signaling ...
arxiv  

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