Results 131 to 140 of about 5,109,346 (334)

KRAS: The Critical Driver and Therapeutic Target for Pancreatic Cancer.

open access: yesCold Spring Harbor Perspectives in Medicine, 2018
RAS genes (HRAS, KRAS, and NRAS) comprise the most frequently mutated oncogene family in human cancer. With the highest RAS mutation frequencies seen with the top three causes of cancer deaths in the United States (lung, colorectal, and pancreatic cancer)
Andrew M. Waters, C. Der
semanticscholar   +1 more source

The role of circular RNAs in regulating cytokine signaling in cancer

open access: yesFEBS Open Bio, EarlyView.
Cytokines present in the tumor microenvironment fuel cancer development. Aberrant expression of circRNAs contributes to cancer progression. Cytokines are involved in regulating circRNA biogenesis. Furthermore, aberrantly expressed circRNAs regulate the expression of ligands, receptors, and downstream effectors involved in cytokine signaling to promote ...
Vandana Joshi   +4 more
wiley   +1 more source

Laparoscopic left lateral sectionectomy for a patient with right-sided ligamentum teres

open access: yesSurgical Case Reports, 2019
Background A right-sided ligamentum teres (RSLT) is a rare congenital anomaly in which the fetal umbilical vein is connected to the right paramedian trunk. RSLT creates difficulty in liver resection with respect to decision-making regarding the resection
Fumihiro Terasaki   +7 more
doaj   +1 more source

Current trends in single‐cell RNA sequencing applications in diabetes mellitus

open access: yesFEBS Open Bio, EarlyView.
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian   +6 more
wiley   +1 more source

Association Between Inherited Germline Mutations in Cancer Predisposition Genes and Risk of Pancreatic Cancer

open access: yesJournal of the American Medical Association (JAMA), 2018
Importance Individuals genetically predisposed to pancreatic cancer may benefit from early detection. Genes that predispose to pancreatic cancer and the risks of pancreatic cancer associated with mutations in these genes are not well defined.
Chunling Hu   +18 more
semanticscholar   +1 more source

Metastatic Pancreatic Cancer

open access: yesJournal of Investigative Surgery, 2017
According to estimates from 2015, approximately 48,960 new pancreatic cancer cases had occurred, and around 40,560 patients had died from pancreatic cancer in the United States of America.
Adam Durczyński   +2 more
openaire   +3 more sources

Matrix: a complex amalgam of structures and functions in tumor microenvironment

open access: yesFEBS Open Bio, EarlyView.
The matrix is a dynamic, intricate three‐dimensional mesh of biomolecules with both structural and functional properties. This review deals with the complexity of this ‘molecular amalgam’ in the tumor microenvironment and highlights its importance in the maintenance and evolution of tumors by describing certain matrix biomolecules, such as ...
Spyros S. Skandalis   +3 more
wiley   +1 more source

A cohort analysis of pancreatic cancer, 1939–1969 [PDF]

open access: bronze, 1977
Melvin A. Benarde, William A. Weiss
openalex   +1 more source

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