Results 151 to 160 of about 10,020,739 (382)

Pancreatic steatosis and metabolic pancreatic disease: a new entity? [PDF]

open access: yesIntern Emerg Med, 2023
Caldart F   +4 more
europepmc   +1 more source

Characterization of WAC interactions with R2TP and TTT chaperone complexes linking glucose and glutamine availability to mTORC1 activity

open access: yesFEBS Open Bio, EarlyView.
TTT and R2TP chaperone complexes are required for the assembly and activation of mTORC1. WAC directly interacts with components of TTT, R2TP, and mTORC1, and these interactions are affected by the availability of glucose and glutamine, correlating with changes in mTORC1 activity.
Sofía Cabezudo   +11 more
wiley   +1 more source

Downregulation of sST2, a decoy receptor for interleukin‐33, enhances subcutaneous tumor growth in murine pancreatic cancer cells

open access: yesFEBS Open Bio, EarlyView.
Subcutaneous implantation of murine Panc02 pancreatic cancer cells depleted of sST2, a soluble decoy receptor for the proinflammatory interleukin‐33 (IL‐33), leads to a decreased number of GLUT4‐positive cancer‐associated adipocytes, reduced levels of the anti‐inflammatory molecule adiponectin, increased phosphorylation of IκBα, elevated Cxcl3 ...
Miho Akimoto   +5 more
wiley   +1 more source

Mannan-Decorated Lipid Calcium Phosphate Nanoparticle Vaccine Increased the Antitumor Immune Response by Modulating the Tumor Microenvironment

open access: yesJournal of Functional Biomaterials
With the rapid development of tumor immunotherapy, nanoparticle vaccines have attracted much attention as potential therapeutic strategies. A systematic review and analysis must be carried out to investigate the effect of mannose modification on the ...
Liusheng Wu   +5 more
doaj   +1 more source

Lundh test and ERCP in pancreatic disease. [PDF]

open access: bronze, 1978
M G Ashton, A T Axon, D.J. Lintott
openalex   +1 more source

Metastatic chordoma with pancreatic disease and response to imatinib. [PDF]

open access: yesBMJ Case Rep, 2022
Klejnow EV   +3 more
europepmc   +1 more source

Stromagenesis and cancer‐associated fibroblast heterogeneity in primary tumors and metastasis: focus in non‐small cell lung cancer

open access: yesFEBS Open Bio, EarlyView.
Cancer‐associated fibroblasts (CAFs) play different roles in NSCLC progression and metastasis. Their heterogeneous origins and phenotypes shape the tumor microenvironment and influence metastatic spread. This review highlights NSCLC CAF subtypes, their potential cellular sources, and their differential distribution across primary tumors and distant ...
Alejandro Bernardo   +3 more
wiley   +1 more source

Innate Lymphoid Cells: Emerging Players in Pancreatic Disease. [PDF]

open access: yesInt J Mol Sci, 2022
Shi S, Ye L, Jin K, Xiao Z, Yu X, Wu W.
europepmc   +1 more source

Statins induce monocytic differentiation in acute myeloid leukemia cells through the KLF4/DPYSL2A axis

open access: yesFEBS Open Bio, EarlyView.
Statins, identified via the Comparative Toxicogenomics Database, promote monocytic differentiation and apoptosis in non‐APL AML cells by upregulating DPYSL2A through a KLF4‐dependent pathway. Mevalonate supplementation reversed these effects, indicating involvement of the mevalonate pathway.
Mina Noura   +7 more
wiley   +1 more source

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