LMO7 Suppresses Tumor‐Associated Macrophage Phagocytosis of Tumor Cells Through Degradation of LRP1
LMO7 in tumor‐associated macrophages suppresses phagocytosis of tumor cells and limits cytotoxic T lymphocytes infiltration, fostering tumor progression. Mechanistically, LMO7 mediates the ubiquitination and degradation of the phagocytic receptor LRP1, impairing its ability to engulf tumor cells and driving macrophages toward an antitumor phenotype ...
Mengkai Li +12 more
wiley +1 more source
Unveiling CTRB2, RSPO3, KLOTB, and ROR1 as obesity-pancreatic disease association proteins: a comprehensive Mendelian randomization study. [PDF]
Zhou C +10 more
europepmc +1 more source
Early pancreatic cancer: the methods currently available can identify this disease?
José Celso Ardengh +2 more
openalex +1 more source
4. Chronic Pancreatitis and Pancreatic Cancer,Lifestyle-Related Diseases
Makoto Otsuki, Mitsuo Tashiro
openalex +2 more sources
XIAP Stabilizes DDRGK1 to Promote ER‐Phagy and Protects Against Noise‐Induced Hearing Loss
Mechanism of GAS‐mediated protection against noise‐induced hearing loss (NIHL). Noise exposure activates the ATF4/eIF2α axis, downregulating XIAP and promoting DDRGK1 degradation, thereby inhibiting ER‐phagy and leading to hair cell (HC) death. GAS treatment rescues XIAP and DDRGK1 expression, reactivating ER‐phagy to mitigate HC loss, synaptic damage,
Lin Yan +13 more
wiley +1 more source
Based on the immune system: the role of the IL-2 family in pancreatic disease. [PDF]
Zhu Y, Lu Z, Wang Z, Liu J, Ning K.
europepmc +1 more source
Gastrointestinal Bleeding due to Pancreatic Disease-Related Portal Hypertension. [PDF]
Zheng K +10 more
europepmc +1 more source
An evaluation of DUPAN-2 in pancreatic cancer and gastrointestinal disease [PDF]
E H Cooper, MA Forbes, Mark Taylor
openalex +1 more source
Mature red blood cells (RBCs) can capture extracellular DNA, with short fragments homologous to cfDNA. This uptake is mediated by apoptotic bodies, which induce RBC oxidative stress, deformation, and accelerated in vivo clearance. The rbcDNA abundance correlates with tumor burden and therapeutic response, highlighting its potential as a liquid biopsy ...
Zihang Zeng +20 more
wiley +1 more source
Comparison of safety and effectiveness between endoscopic ultrasound-guided and ultrasound-guided pancreatic biopsy in focal pancreatic disease: a multi-center, retrospective, propensity score analysis. [PDF]
Chai W +7 more
europepmc +1 more source

