Results 41 to 50 of about 9,801,285 (428)

Adjuvant therapy with gemcitabine and stereotactic body radiation therapy versus gemcitabine alone for resected stage II pancreatic cancer: a prospective, randomized, open-label, single center trial

BMC Cancer, 2022
Background The role of adjuvant radiation in pancreatic adenocarcinoma (PDAC) remains unclear. We aimed to investigate the efficacy of gemcitabine combined with stereotactic body radiation therapy (SBRT) as adjuvant therapy for resected stage II PDAC ...
Tao Ma, Xueli Bai, Qichun Wei, Yongjie Shui, Mengyi Lao, Wen Chen, Bingfeng Huang, Risheng Que, Shunliang Gao, Yun Zhang, Wei Chen, Ji Wang, Tingbo Liang   +12 more
doaj   +1 more source

Systematic Characterization of the Clinical Relevance of KPNA4 in Pancreatic Ductal Adenocarcinoma

Frontiers in Oncology, 2022
BackgroundPancreatic ductal adenocarcinoma (PDAC) is one of the most lethal malignancies with poor prognosis. Karyopherin subunit alpha 4 (KPNA4) is a nuclear transport factor and plays tumor-promoting roles in multiple cancers.
Jingpiao Bao, Jingpiao Bao, Chaoliang Xu, Bin Li, Bin Li, Zengkai Wu, Zengkai Wu, Jie Shen, Jie Shen, Pengli Song, Pengli Song, Qi Peng, Qi Peng, Guoyong Hu, Guoyong Hu   +14 more
doaj   +1 more source

Targeting ROCK activity to disrupt and prime pancreatic cancer for chemotherapy [PDF]

, 2017
Pancreatic ductal adenocarcinoma (PDAC) is a devastating disease; the identification of novel targets and development of effective treatment strategies are urgently needed to improve patient outcomes.
Olson, Michael F., Pajic, Marina, Rath, Nicola, Timpson, Paul, Vennin, Claire   +4 more
core   +1 more source

Preoperative plasma D-dimer independently predicts survival in patients with pancreatic ductal adenocarcinoma undergoing radical resection

World Journal of Surgical Oncology, 2021
Background Elevated plasma D-dimer levels have been reported as an unfavorable prognostic indicator in many solid tumors. However, there are limited relevant studies in pancreatic cancer patients following radical surgery, and the clinical significance ...
Haoda Chen, Fanlu Li, Siyi Zou, Junjie Xie, Jun Zhang, Xiaxing Deng, Hao Chen, Baiyong Shen   +7 more
doaj   +1 more source

DeformableFormer: Classification of Endoscopic Ultrasound Guided Fine Needle Biopsy in Pancreatic Diseases [PDF]

arXiv, 2023
Endoscopic Ultrasound-Fine Needle Aspiration (EUS-FNA) is used to examine pancreatic cancer. EUS-FNA is an examination using EUS to insert a thin needle into the tumor and collect pancreatic tissue fragments. Then collected pancreatic tissue fragments are then stained to classify whether they are pancreatic cancer.
arxiv  

STUDIES IN PANCREATIC DISEASE [PDF]

Archives of Internal Medicine, 1915
PART I.—DUODENAL CONTENT ANALYSES AS AN INDEX OF DISEASE, AND FUNCTIONAL ACTIVITY OF THE PANCREAS A reliable method for ascertaining the functional activity of the pancreas, has been eagerly sought for the last few decades, in fact since the time that Kuntzman, Richard Bright and Claude Bernard first called attention to this gland as a possible focus ...
openaire   +3 more sources

Mutant p53R270H drives altered metabolism and increased invasion in pancreatic ductal adenocarcinoma [PDF]

, 2018
Pancreatic cancer is characterized by nearly universal activating mutations in KRAS. Among other somatic mutations, TP53 is mutated in more than 75% of human pancreatic tumors.
Daylan, Ayse Ece Cali, Del Vecchio, Annachiara, Espinoza, Carlos, Fabo, Tania, Fearon, Eric R., Feng, Ying, Galbán, Stefanie, Halbrook, Christopher J., Karim, Saadia A., Kovalenko, Ilya, Kremer, Daniel M., Kumar-Sinha, Chandan, Lee, Ho-Joon, Ljungman, Mats, Lyssiotis, Costas A., Magnuson, Brian, Morton, Jennifer P., Pasca di Magliano, Marina, Schofield, Heather K., Yan, Wei, Zeller, Jörg   +20 more
core   +1 more source

Primary extranodal diffuse large B‐cell lymphoma: Molecular features, treatment, and prognosis

Aging and Cancer, Volume 3, Issue 3-4, Page 133-146, September-December 2022., 2022
One‐third of DLBCL arises from extranodal organs and is challenging to manage. Molecular features are critical to elucidate the differences in clinical features, predict the disease prognosis, and improve effective targeted therapeutic strategies. Abstract Diffuse large B‐cell lymphoma (DLBCL) is the most common subtype of non‐Hodgkin's lymphoma and ...
Si‐Yuan Chen, Meng‐Meng Ji, Peng‐Peng Xu, Wei‐Li Zhao   +3 more
wiley   +1 more source

Postoperative hyperprogression disease of pancreatic ductal adenocarcinoma after curative resection: a retrospective cohort study

BMC Cancer, 2022
Background Prognosis for patients recurred rapidly after resection of pancreatic ductal adenocarcinoma (PDAC) was extremely poor. We proposed the concept of postoperative hyper-progression disease (PO-HPD) to define recurrence within 2 months after ...
Siyi Zou, Xinjing Wang, Haoda Chen, Jiewei Lin, Chenlei Wen, Qian Zhan, Hao Chen, Xiongxiong Lu, Xiaxing Deng, Baiyong Shen   +9 more
doaj   +1 more source

Haemorrhage in pancreatic disease

Journal of British Surgery, 1989
Abstract Haemorrhage is a life-threatening complication in pancreatic disease. Twenty-five patients with this complication are described; 15 had major bleeding, nine had minor bleeding and one patient had a pseudoaneurysm identified at operation.
S. Shankar, R. C. G. Russell
openaire   +3 more sources