Results 71 to 80 of about 9,605,816 (285)

Enhancing the prediction of disease outcomes using electronic health records and pretrained deep learning models [PDF]

arXiv, 2022
Question: Can an encoder-decoder architecture pretrained on a large dataset of longitudinal electronic health records improves patient outcome predictions? Findings: In this prognostic study of 6.8 million patients, our denoising sequence-to-sequence prediction model of multiple outcomes outperformed state-of-the-art models scuh pretrained BERT on a ...
arxiv  

Obesity and Pancreatic Diseases

The Korean Journal of Gastroenterology, 2012
Obesity is defined as BMI (calculated as weight in kg divided by height in m2) more than 30, and overweight is defined as BMI of 25-29.9. Obesity has been considered as a risk factor for pancreatic diseases, including pancreatitis and pancreatic cancer. Severe acute pancreatitis is significantly more frequent in obese patients.
Ho Gak Kim, Jimin Han
openaire   +2 more sources

Predicting the risk of pancreatic cancer with a CT-based ensemble AI algorithm [PDF]

arXiv, 2020
Objectives: Pancreatic cancer is a lethal disease, hard to diagnose and usually results in poor prognosis and high mortality. Developing an artificial intelligence (AI) algorithm to accurately and universally predict the early cancer risk of all kinds of pancreatic cancer is extremely important.
arxiv  

Pancreatitis and atypical Kawasaki disease [PDF]

Pediatric Rheumatology, 2010
Abstract We report on pediatric patient with clinical and laboratory evidence of pancreatitis at onset of atypical Kawasaki disease (KD). In KD pancreatic inflammation was described previously, but clinical pancreatitis was rarely reported and its true incidence is unknown. In febrile pediatric patients suspected to have KD, but not
Zoran Paunovic, Goran Ristic, Dragan Prokic, Srdjan Pasic   +3 more
openaire   +4 more sources

The role of complement in the clinical course of hepatocellular carcinoma

Immunity, Inflammation and Disease, 2022
Background The complement system, an innate immune system, may either play an antitumor role, or promote tumorigenesis and cancer progression in different kinds of cancer. The function of complement in hepatocellular carcinoma (HCC) is unclear.
Xinye Qian, Zhoujing Yang, Lu Gao, Yipiao Liu, Jun Yan   +4 more
doaj   +1 more source

Personalized pancreatic cancer therapy: from the perspective of mRNA vaccine

Military Medical Research, 2022
Pancreatic cancer is characterized by inter-tumoral and intra-tumoral heterogeneity, especially in genetic alteration and microenvironment. Conventional therapeutic strategies for pancreatic cancer usually suffer resistance, highlighting the necessity ...
Xing Huang, Gang Zhang, Tian-Yu Tang, Xiang Gao, Ting-Bo Liang   +4 more
doaj   +1 more source

Risk factors for suicide in patients with pancreatic ductal adenocarcinoma: A population‐based study

Aging and Cancer
Background Patients diagnosed with pancreatic ductal adenocarcinoma (PDAC) face a notable risk of suicide. However, comprehensive population‐based studies on suicide risk in PDAC patients have been lacking. This study seeks to explore the suicide risk in
Chao Wang, Haoda Chen, Yuanchi Weng, Xiaxing Deng, Weishen Wang, Baiyong Shen   +5 more
doaj   +1 more source

mRNA vaccines in disease prevention and treatment

Signal Transduction and Targeted Therapy, 2023
mRNA vaccines have emerged as highly effective strategies in the prophylaxis and treatment of diseases, thanks largely although not totally to their extraordinary performance in recent years against the worldwide plague COVID-19.
Gang Zhang, Tianyu Tang, Yinfeng Chen, Xing Huang, Tingbo Liang   +4 more
doaj   +1 more source

Maintenance Olaparib for Germline BRCA-Mutated Metastatic Pancreatic Cancer.

New England Journal of Medicine, 2019
BACKGROUND Patients with a germline BRCA1 or BRCA2 mutation make up a small subgroup of those with metastatic pancreatic cancer. The poly(adenosine diphosphate-ribose) polymerase (PARP) inhibitor olaparib has had antitumor activity in this population ...
T. Golan, P. Hammel, M. Reni, E. Van Cutsem, T. Macarulla, M. Hall, Joon-Oh Park, D. Hochhauser, D. Arnold, D. Oh, A. Reinacher-Schick, G. Tortora, H. Algül, E. O’Reilly, D. McGuinness, K. Cui, K. Schlienger, G. Locker, H. Kindler   +18 more
semanticscholar   +1 more source

Risk factors for and prognostic values of postoperative acute kidney injury after pancreaticoduodenectomy for pancreatic ductal adenocarcinoma: A retrospective, propensity score‐matched cohort study of 1312 patients

Cancer Medicine, 2023
Background While an association between postoperative acute kidney injury (AKI) and adverse events exists, the incidence and impact of postoperative AKI after pancreaticoduodenectomy for pancreatic ductal adenocarcinoma remain unclear.
Yuchen Ji, Yiran Zhou, Ziyun Shen, Haoda Chen, Shulin Zhao, Xiaxing Deng, Baiyong Shen   +6 more
doaj   +1 more source