Results 141 to 150 of about 861,864 (406)

Pathomics Signature for Prognosis and CA19‐9 Interception in Pancreatic Ductal Adenocarcinoma: A Real‐Life, Multi‐Center Study

open access: yesAdvanced Science, EarlyView.
This study develops a deep learning‐based pathomics model to predict survival outcomes in pancreatic cancer patients. The CrossFormer architecture analyzes routine H&E‐stained tissue slides, identifying key prognostic features including stromal patterns, cellular characteristics, and immune infiltration.
Qiangda Chen   +22 more
wiley   +1 more source

S3RL: Enhancing Spatial Single‐Cell Transcriptomics With Separable Representation Learning

open access: yesAdvanced Science, EarlyView.
Separable Spatial Representation Learning (S3RL) is introduced to enhance the reconstruction of spatial transcriptomic landscapes by disentangling spatial structure and gene expression semantics. By integrating multimodal inputs with graph‐based representation learning and hyperspherical prototype modeling, S3RL enables high‐fidelity spatial domain ...
Laiyi Fu   +6 more
wiley   +1 more source

STUDI HISTOKIMIA SEBARAN KARBOHIDRAT PADA PANKREAS AYAM KAMPUNG (GALLUS GALLUS DOMESTICUS)DAN ITIK MUSKOVI (CAIRINA MOSCHATA) HISTOCHEMICAL STUDY OF CARBOHYDRATE DISTRIBUTION OF PANCREAS IN DOMESTIC CHICKEN (GALLUS GALLUS DOMESTICUS) AND MUSCOVY DUCK (CAIRINA MOSCHATA) [PDF]

open access: yes, 2017
Penelitian ini bertujuan mengetahui sebaran karbohidrat pada pankreas ayam kampung dan itik muskovi secara histokimia. Penelitian ini menggunakan pankreas ayam kampung dan itik muskovi masing-masing tiga ekor dan diproses secara mikroteknik dengan ...
Jauhar Latif Arba
core  

GOT1 Inhibition Induces Extracellular Matrix Remodeling in Pancreatic Cancer

open access: yesAdvanced Science, EarlyView.
Using tumor tissue engineering, we recreated pancreatic cancer and found that inhibiting glutamic‐oxaloacetic transaminase 1 (GOT1) induces extracellular matrix remodeling and secretome rewiring, as well as promotes cell death. ABSTRACT Pancreatic cancer cells rely on glutamine to sustain their survival in the stiff and poorly vascularized tumor ...
Rodrigo Curvello   +10 more
wiley   +1 more source

Mass-forming type 2 autoimmune pancreatitis with upstream dilatation of the main pancreatic duct dilatation: a case report

open access: yesJournal of Medical Case Reports
Background Type 2 autoimmune pancreatitis is characterized by multiple or segmental strictures of the main pancreatic duct without upstream dilatation.
Noriyuki Tagai   +3 more
doaj   +1 more source

Intraductal papillary mucinous neoplasm (IPMN):UPDATE [PDF]

open access: yes, 2015
At present, IPMN is broadly divided into two main types: main duct and branch duct. However, as discussed below, the definition of mixed-type IPMN is gradually becoming accepted.
木村 理
core   +1 more source

Deep Learning‐Powered Scalable Cancer Organ Chip for Cancer Precision Medicine

open access: yesAdvanced Science, EarlyView.
This scalable, low‐cost Organ Chip platform, made via injection molding, uses capillary pinning for hydrogel confinement and supports versatile tissue coculture and robust imaging. Deep learning enables label‐free, sensitive phenotypic analysis.
Yu‐Chieh Yuan   +24 more
wiley   +1 more source

Calcium Channel Blockers Inhibit Pancreatic Neuroendocrine Neoplasms Progression via Cav1.2‐Epigenetic Circuit

open access: yesAdvanced Science, EarlyView.
Our study reveals a novel mechanism of a positive regulatory circuit between Cav1.2 and H3K27ac for pancreatic neuroendocrine neoplasms (pNENs) progression. Cav1.2 is identified as a crucial target for promoting disease progression and correlates with malignant behaviors, which are remarkably inhibited by the administration of calcium channel blockers (
Yangyinhui Yu   +12 more
wiley   +1 more source

An Automated Prognostic Model for Pancreatic Ductal Adenocarcinoma [PDF]

open access: gold, 2023
Ioannis Vezakis   +6 more
openalex   +1 more source

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