Results 161 to 170 of about 83,141 (294)

Bioprinted Organoids: An Innovative Engine in Biomedicine

Advanced Science, EarlyView.
Bioprinted organoids refer to either the printing of stem cells into tissue shape and subsequent differentiate into organoids, or assembling induced organoids as bioinks to replicate native organ. It enables the creation of miniaturized organs with complex architectures and physiological functions, potentially enhancing reproducibility, throughput, and
Zhengwei Li, Kai Li, Cheng Zhang, Yingying Zhao, Yiyuan Guo, Jia He, Shiyuan Chang, Xinyi Fang, Kaizheng Liu, Pingping Zhu, Zhenzhen Chen, Changshun Ruan   +11 more
wiley   +1 more source

Middle Pancreatectomy for Traumatic Main Pancreatic Duct Injury with Delayed Presentation: Two Case Series. [PDF]

Surg Case Rep
Itagaki Y, Takeuchi S, Noji T, Ebihara Y, Wada M, Tanaka K, Matsui A, Nakanishi Y, Asano T, Nakamura T, Hirano S.   +10 more
europepmc   +1 more source

SenExo‐cCCT2 Reprograms Senescence Response and Anti‐Tumor Immunity Following FOLFIRINOX Chemotherapy in Pancreatic Ductal Adenocarcinoma

Advanced Science, EarlyView.
This study demonstrates that SenExo‐cCCT2 enables targeted delivery of cCCT2 to pancreatic cancer cells, where it disrupts IPO13‐mediated nuclear translocation of UBC9, impairing SUMOylation‐dependent DNA damage repair and inducing senescence. Senescent tumor cells secrete CXCL10 to recruit CD8⁺ T‐cells while upregulating PD‐L1.
Shuncang Zhu, Yinhao Chen, Hongyi Lin, Jinpeng Lu, Yu Pan, Ge Li, Yongding Wu, Haoxiang Zhang, Xiaoxiao Huang, Yiting Chen, Huangjing Chen, Long Jin, Min Huang, Chengyu Liao, Long Huang, Yifeng Tian, Zuwei Wang, Qiaowei Li, Shi Chen   +18 more
wiley   +1 more source

3D Imaging Resolves Human Pancreatic Duct-β-Cell Clusters During Cystic Change. [PDF]

Diabetes
Lee CY, Kuo TC, Chou YH, Peng SJ, Hsiao FT, Chung MH, Lo LW, Shen CN, Chien HJ, Chang HP, Chen CC, Jeng YM, Tien YW, Tang SC.   +13 more
europepmc   +1 more source

Calcium carbonate saturation in human pancreatic juice: Possible role of ductal H+ secretion

, 1989
A. Gérolami, C. Marteau, Antonia De Matteo, José‐Alain Sahel, H. Portugal, A Pauli, J. Pastor, H Sarles   +7 more
openalex   +1 more source

Regulating Enzyme Activity via Microaggregates Mediated by Phase Separation

Advanced Science, EarlyView.
An enzyme‐sequestration strategy for combating postoperative pancreatic fistula (POPF) is developed, employing a D‐peptide called DPMD to induce liquid–solid phase separation (LSPS) of pancreatic proteases. This LSPS‐driven microaggregate approach effectively isolates trypsin and chymotrypsin from their substrates, thereby reducing pancreatic fluid ...
Yang Wang, Juzheng Yuan, Niu Dai, Yanlin Ji, Wenguang Yang, Xiao Li, Siqi Yan, Jin Yan   +7 more
wiley   +1 more source

Successful bridging disconnected pancreatic duct syndrome complicated by plastic stent-induced bowel perforation. [PDF]

Endoscopy
Zhang G, Ma M, Wang YF, Ma R, Li H, Li Z, Zhong N.   +6 more
europepmc   +1 more source

Effect of Secretin and VIP on Isolated Pancreatic Duct Fragments <I>IN VITRO</I>

, 1980
W. Creutzfeldt, Ulrich R. Foelsch
openalex   +2 more sources

Mixed Lineage Kinase Domain‐Like Protein (MLKL): From Mechanisms to Therapeutic Opportunities

Advanced Science, EarlyView.
The mixed lineage kinase domain‐like protein (MLKL) acts as the executioner in the necroptosis pathway, transitioning from an inactive to active state through phosphorylation, oligomerization, membrane recruitment, and membrane insertion, ultimately forming membrane hotpots.
Lijuan Xu, Chunlin Zhuang
wiley   +1 more source

Novel method to remove deeply migrated pancreatic duct stent with caudal end embedded in the pancreas. [PDF]

Endoscopy
Song L, Cheng F, Liu X, Liu Y, Qu H, Sun S, Tian Q.   +6 more
europepmc   +1 more source