Results 41 to 50 of about 861,864 (406)

A novel protein isoform of the RON tyrosine kinase receptor transforms human pancreatic duct epithelial cells. [PDF]

open access: yes, 2016
The MST1R gene is overexpressed in pancreatic cancer producing elevated levels of the RON tyrosine kinase receptor protein. While mutations in MST1R are rare, alternative splice variants have been previously reported in epithelial cancers.
Babicky, M   +10 more
core   +2 more sources

Pancreatitis: the neglected duct

open access: yesGut, 2008
Acute and chronic pancreatitis are multifactorial diseases that involve inflammation of the pancreas, generation of toxic mediators and mistargeting of digestive enzymes that eventually result in destruction of the parenchyma.1 Because acinar cells contain the harmful mistargeted digestive enzymes and the extensive damage occurs in acinar cells in all ...
Min Goo, Lee, Shmuel, Muallem
openaire   +3 more sources

Endoscopic ultrasonography-guided drainage for patients with symptomatic obstruction and enlargement of the pancreatic duct.

open access: yesWorld Journal of Gastroenterology, 2015
AIM To evaluate the use of translumenal pancreatography with placement of endoscopic ultrasonography (EUS)-guided drainage of the pancreatic duct. METHODS This study enrolled all consecutive patients between June 2002 and April 2014 who underwent EUS ...
U. Will   +3 more
semanticscholar   +1 more source

Comparison of the diagnostic accuracy of three current guidelines for the evaluation of asymptomatic pancreatic cystic neoplasms. [PDF]

open access: yes, 2017
Asymptomatic pancreatic cysts are a common clinical problem but only a minority of these cases progress to cancer. Our aim was to compare the accuracy to detect malignancy of the 2015 American Gastroenterological Association (AGA), the 2012 International
Aslanian, Harry   +17 more
core   +2 more sources

Main pancreatic duct dilatation and pancreatic cysts in relatives and spouses of patients with pancreatic cancer

open access: yesPLoS ONE, 2023
Although main pancreatic duct dilatation and pancreatic cysts are risk factors for developing pancreatic cancer, limited data exist regarding these findings in relatives and spouses of pancreatic cancer patients.
Kenji Ikezawa   +7 more
doaj   +3 more sources

Main pancreatic duct 360° denudation technique for local resection of solid pseudopapillary tumor: a case report

open access: yesJournal of Pancreatology
Pancreatic enucleation is a reasonable surgical procedure for small pancreatic solid pseudopapillary tumors (SPTs). For patients with tumors close to the main pancreatic duct, enucleation surgery was previously considered contraindicated.
Li Liu   +3 more
doaj   +1 more source

Pseudocyst in the Pancreatic Tail Associated with Chronic Pancreatitis Successfully Treated by Transpapillary Cyst Drainage

open access: yesCase Reports in Gastroenterology, 2008
We report a 50-year-old male with pseudocysts in the pancreatic tail associated with chronic pancreatitis successfully treated by transpapillary cyst drainage. He had previously undergone ultrasonography-guided percutaneous cyst drainage for a pancreatic
Itaru Naitoh   +12 more
doaj   +1 more source

Theoretical investigation of transgastric and intraductal approaches for ultrasound-based thermal therapy of the pancreas. [PDF]

open access: yes, 2017
BackgroundThe goal of this study was to theoretically investigate the feasibility of intraductal and transgastric approaches to ultrasound-based thermal therapy of pancreatic tumors, and to evaluate possible treatment strategies.MethodsThis study ...
Adams, Matthew S   +4 more
core   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

EUS-Guided Pancreatic Cyst Ablation: a Clinical and Technical Review [PDF]

open access: yes, 2019
Purpose of Review Pancreatic cystic lesions represent a growing public health dilemma, particularly as our population ages and cross-sectional imaging becomes more sensitive.
DeWitt, John M.   +2 more
core   +1 more source

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