Results 241 to 250 of about 54,964 (316)
The Role of Endothelin‐1 in Autoimmune Diseases: Mechanistic Insights and Therapeutic Targets
The Role of Endothelin‐1 in Autoimmune Diseases. NF‐κB: nuclear factor kappa‐B; MAPK: mitogen‐activated protein kinase; PI3K: phosphoinositide 3‐kinase; ROS: reactive oxygen species; CTGF: connective tissue growth factor; TGF‐β: transforming growth factor‐β.
Xun Gong +5 more
wiley +1 more source
The consequences of percutaneous transhepatic biliary drainage (PTBD) in patients with tumoral obstructive jaundice: A retrospective study and review of literature. [PDF]
Jalili J +7 more
europepmc +1 more source
This study develops an interpretable gradient‐boosting model that accurately identifies drug‐induced liver injury (DILI) using routine laboratory data. The model explains key clinical features through SHapley Additive exPlanations analysis and detects DILI earlier than expert evaluation, offering a transparent and practical tool for precision ...
Jingyi Ling +13 more
wiley +1 more source
The emerging role of pancreatic exocrine fibrosis as a common aetiological driver of islet dysfunction and diabetes: opportunities for novel disease-modifying interventions. [PDF]
Kattner N, Bashir A, Shaw JAM.
europepmc +1 more source
Overview of a DNA methylation biomarker development pipeline, from discovery and assay design to screening, performance evaluation, and specificity testing in clinical sample matrices. ABSTRACT Background Tissue‐specific cell‐free DNA (cfDNA) offers promise as a minimally invasive biomarker of organ injury.
David H. Murray +6 more
wiley +1 more source
The assay exploited a multiparametric and fully automated device applied to CHORUS EVO to validate that the CHORUS Macroarray Liver Diseases kit is a novel procedure for detecting autoantibodies of AIH and PBC. The assay resulted as linear, accurate, sensitive, specific, and able to distinguish between PBC and AIH.
Luigi Raganelli +14 more
wiley +1 more source
Diagnostic dilemma in gastroduodenal lesions: Heterotopic pancreas mimicking gastrointestinal stromal tumours managed by minimally invasive approach - A case series and review of the literature. [PDF]
Raghavendra D +6 more
europepmc +1 more source
ABSTRACT Background Between 2002 and 2013, we performed pancreatoduodenectomy (PD) with combined resection of the superior mesenteric artery (SMA) (PD‐SMAR) to treat locally advanced pancreatic head cancer (PHC). Since 2011, we have performed PD with circumferential lymph node dissection along the SMA (PD‐CLDS), in which we dissected lymph nodes all ...
Isamu Makino +9 more
wiley +1 more source

