Results 241 to 250 of about 54,964 (316)

Pancreatic duct diameter

open access: yes, 2013
Yuranga Weerakkody   +2 more
openaire   +1 more source

The Role of Endothelin‐1 in Autoimmune Diseases: Mechanistic Insights and Therapeutic Targets

open access: yesiNew Medicine, EarlyView.
The Role of Endothelin‐1 in Autoimmune Diseases. NF‐κB: nuclear factor kappa‐B; MAPK: mitogen‐activated protein kinase; PI3K: phosphoinositide 3‐kinase; ROS: reactive oxygen species; CTGF: connective tissue growth factor; TGF‐β: transforming growth factor‐β.
Xun Gong   +5 more
wiley   +1 more source

Interpretable machine learning enables early and accurate detection of drug‐induced liver injury: A multicenter study with real‐world clinical translation

open access: yesInterdisciplinary Medicine, EarlyView.
This study develops an interpretable gradient‐boosting model that accurately identifies drug‐induced liver injury (DILI) using routine laboratory data. The model explains key clinical features through SHapley Additive exPlanations analysis and detects DILI earlier than expert evaluation, offering a transparent and practical tool for precision ...
Jingyi Ling   +13 more
wiley   +1 more source

From DNA Methylation Microarray to Digital PCR: A Stepwise Strategy for Tissue Specific cfDNA Biomarker Development

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
Overview of a DNA methylation biomarker development pipeline, from discovery and assay design to screening, performance evaluation, and specificity testing in clinical sample matrices. ABSTRACT Background Tissue‐specific cell‐free DNA (cfDNA) offers promise as a minimally invasive biomarker of organ injury.
David H. Murray   +6 more
wiley   +1 more source

Validation of a Multiparametric, Automated, Macroarray‐Based Assay for the Detection of Autoantibodies in Autoimmune Liver Disease

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
The assay exploited a multiparametric and fully automated device applied to CHORUS EVO to validate that the CHORUS Macroarray Liver Diseases kit is a novel procedure for detecting autoantibodies of AIH and PBC. The assay resulted as linear, accurate, sensitive, specific, and able to distinguish between PBC and AIH.
Luigi Raganelli   +14 more
wiley   +1 more source

Liver, biliary tract, and pancreas [PDF]

open access: yes, 1964
Hermann, G, Starzl, TE
core  

Status of Lymph Node Metastasis and Efficacy of Lymph Node Dissection Along the Superior Mesenteric Artery in Pancreatic Head Cancer: Clinicopathological Analysis of Patients Undergoing Pancreatoduodenectomy With Circumferential Lymph Nodes Dissection Along the Superior Mesenteric Artery

open access: yesJournal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
ABSTRACT Background Between 2002 and 2013, we performed pancreatoduodenectomy (PD) with combined resection of the superior mesenteric artery (SMA) (PD‐SMAR) to treat locally advanced pancreatic head cancer (PHC). Since 2011, we have performed PD with circumferential lymph node dissection along the SMA (PD‐CLDS), in which we dissected lymph nodes all ...
Isamu Makino   +9 more
wiley   +1 more source

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