ABSTRACT Arthrogryposis Multiplex Congenita (AMC) encompasses several hundred conditions with diverse genetic, pathophysiological, and clinical origins. The overarching EXPLAIN study explores underlying causes and implications of AMC and represents the largest clinical cohort of adults with AMC reported to date.
My Vuong Hermansen +5 more
wiley +1 more source
ABSTRACT Objective This study investigated the developmental differences in structure, gene expression, and function of human olfactory epithelium (OE) using pediatric and adult specimens and human olfactory organoids. Background Olfactory dysfunction (OD) is characterized by loss or alterations in the sense of smell and has an age‐related increase in ...
Randy Bach +9 more
wiley +1 more source
Exocrine Pancreatic Insufficiency Following Gastric Resectional Surgery-is Routine Pancreatic Enzyme Replacement Therapy Necessary? [PDF]
Sridhar RP +4 more
europepmc +1 more source
This graphical abstract illustrates the protective role and molecular mechanism of the circadian rhythm‐related gene KLF10, identified as a diagnostic biomarker and therapeutic target in anxiety‐depressive disorder. Model establishment and phenotypes: An anxiety‐depression model was successfully established by chronic restraint stress combined with ...
Anlan Liu +4 more
wiley +1 more source
Pancreatic Enzyme Replacement Therapy in the Course of Chronic Pancreatitis and Pancreatic Cancer [PDF]
E.A. Dubtsova +3 more
openaire +1 more source
Nanofabricated Biomaterials Model Tumor Extracellular Matrix Topography
The unique structure and composition of the tumor microenvironment and its associated extracellular matrix (ECM) exert profound effects on cancer cell behavior that are difficult to model in vitro. This perspective discusses the utility of nanofabricated biosubstrates, such as the novel collagen‐coated nanogrooved array, for recapitulating the ...
Vic Zamloot, JinSeok Park
wiley +1 more source
Methacrylated Gelatin and Graphene Oxide Hybrid Hydrogels Composed‐Bioinks for 3D Tissue Engineering
Bioinks made from hydrogels, such as methacrylated gelatin (GelMA), serve as the base material for bioprinted tissues, offering versatility and biocompatibility for a range of applications. Additional components however are still needed to improve functionality and mechanical stability of hydrogels. One of these components is graphene oxide (GO), added
Wanessa S. Mota +10 more
wiley +1 more source
Nutritional advice for prevention of acute pancreatitis: review of current opinion
Mark E Lowe, Wednesday A SevillaDivision of Pediatric Gastroenterology, Hepatology and Nutrition, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA, USAAbstract: Pancreatitis is inflammation of the pancreas that can be acute and self ...
Lowe ME, Sevilla WA
doaj
Study Design Considerations for the Evaluation of Pancreatic Enzyme Replacement Therapy (PERT) Products in People with Cystic Fibrosis: An Update. [PDF]
Konstan MW +10 more
europepmc +1 more source
Pancreatic Enzyme Replacement Therapy Improves Exclusive Enteral Nutrition Related Diarrhea in Crohn's Disease: A Prospective Randomized Trial. [PDF]
Mammadov S, Yağli MA, Ormeci AC.
europepmc +2 more sources

