Results 11 to 20 of about 130,417 (251)

Comprehensive Analysis of Differentially Expressed lncRNA, circRNA and mRNA and Their ceRNA Networks in Mice With Severe Acute Pancreatitis

open access: yesFrontiers in Genetics, 2021
Severe acute pancreatitis (SAP) is an acute digestive system disease with high morbidity mortality and hospitalization rate worldwide, due to various causes and unknown pathogenesis.
Bing Wang   +17 more
doaj   +1 more source

Isolated Pancreatic Tail Injury in Paediatrics; A Case Report and Literature Review [PDF]

open access: yesBulletin of Emergency and Trauma, 2020
Pancreatic injury in paediatrics is a rare condition and can be difficult to diagnose. The diagnostic challenge is due to its symptom of vague abdominal pain which usually results in late presentation.
Nabil Muhammad Al Kuddoos   +4 more
doaj   +1 more source

Placental chorionic plate-derived mesenchymal stem cells ameliorate severe acute pancreatitis by regulating macrophage polarization via secreting TSG-6

open access: yesStem Cell Research & Therapy, 2021
Background Mesenchymal stem cells (MSCs) hold promising potential to treat systemic inflammatory diseases including severe acute pancreatitis (SAP). In our previous study, placental chorionic plate-derived MSCs (CP-MSCs) were found to possess superior ...
Qilin Huang   +11 more
doaj   +1 more source

N6-Methyladenosine Modification Opens a New Chapter in Circular RNA Biology

open access: yesFrontiers in Cell and Developmental Biology, 2021
As the most abundant internal modification in eukaryotic cells, N6-methyladenosine (m6A) in mRNA has shown widespread regulatory roles in a variety of physiological processes and disease progressions.
Jun Wu   +12 more
doaj   +1 more source

Protective effect of placenta-derived mesenchymal stem cell transplantation against severe acute pancreatitis in rats

open access: yesDi-san junyi daxue xuebao, 2020
Objective To investigate the protective effects of human placenta-derived mesenchymal stem cell (P-MSC) transplantation against severe acute pancreatitis (SAP) in rats.
HUANG Qilin   +6 more
doaj   +1 more source

Severe pancreatic injury with total disruption of main pancreatic duct successfully managed by multi‐stage endoscopic therapy: a case report

open access: yesAcute Medicine & Surgery, 2022
Background The management of pancreatic injury is not well‐established. Recently, endoscopic therapy has been reported as a treatment option for main pancreatic duct disruption.
Kei Ito   +3 more
doaj   +1 more source

CircRNA Expression Profiles and the Potential Role of CircZFP644 in Mice With Severe Acute Pancreatitis via Sponging miR-21-3p

open access: yesFrontiers in Genetics, 2020
Severe acute pancreatitis (SAP) is the most serious type of pancreatitis with high morbidity and mortality. The underlying mechanism behind SAP pathogenesis is complex and remains elusive. Circular RNAs (circRNAs) are emerging as vital regulators of gene
Yi Yang   +14 more
doaj   +1 more source

Efficacy of damage control surgery and staged endoscopic pancreatic ductal double stenting therapy for severe pancreatic head injury: a case report

open access: yesJournal of Medical Case Reports, 2021
Background A high-grade pancreatic injury is a life-threatening injury that is associated with high mortality and morbidity. It is currently unclear which treatment strategy results in good clinical outcomes.
Futoshi Nagashima   +6 more
doaj   +1 more source

Liver and Pancreatic Involvement in Children with Multisystem Inflammatory Syndrome Related to SARS-CoV-2: A Monocentric Study

open access: yesChildren, 2022
Liver and pancreatic involvement in children with Multisystem Inflammatory Syndrome related to SARS-CoV-2 (MIS-C) has been poorly investigated so far.
Antonietta Giannattasio   +9 more
doaj   +1 more source

Imaging of Pancreatic Trauma—A Clinical Scenario-Based Approach

open access: yesJournal of Gastrointestinal and Abdominal Radiology, 2020
Pancreatic injury, although uncommon in the setting of abdominal trauma, is associated with high morbidity and mortality. While the clinical signs are nonspecific, the imaging signs can be very subtle in the early stages leading to missed injuries that ...
Naren Hemachandran   +1 more
doaj   +1 more source

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