Results 91 to 100 of about 1,632 (216)

Trans fatty acids increase nitric oxide levels and pancreatic beta-cell necrosis in rats

open access: yesUniversa Medicina, 2015
BACKGROUND The prevalence of diabetes in Indonesia is increasing due to various factors, including life style changes such as trans fatty acid (TFA) intake. High TFA intake is known to be related to blood lipid profile changes resulting in cardiovascular
Kusmiyati Tjahjono DK   +2 more
doaj   +1 more source

Pancreatic Atrophy: A Narrative Review and Surgical Interpretation

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
Pancreatic parenchymal atrophy pattern and intraoperative margin assessment guide surgical strategy. ABSTRACT Despite recent advances in multimodal management, pancreatic ductal adenocarcinoma remains a fatal malignancy. Early detection of indirect findings of pancreatic ductal adenocarcinoma is essential to improve treatment outcomes, drawing ...
Rika Fujino   +4 more
wiley   +1 more source

Visceral fat lipolysis by pancreatic lipases worsens heart failure

open access: yesCell Reports Medicine
Summary: Heart failure can be worse when associated with obesity, elevated serum pancreatic enzymes, elevated non-esterified fatty acids (NEFAs), or acute pancreatitis (AP).
Nabil Smichi   +13 more
doaj   +1 more source

Stem cell–based therapies for type 1 diabetes: Progress in differentiation, clinical translation, and immune protection

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Directed differentiation of pluripotent stem cells into functional pancreatic β cells have emerged as a promising strategy for the radical treatment of type 1 diabetes, with preclinical and early clinical evidence demonstrating reversal of hyperglycemia and insulin independence.
Zifan Li, Yu Kang, Yuyu Niu
wiley   +1 more source

Walled-off pancreatic necrosis.

open access: yesThe Netherlands journal of medicine, 2012
Acute severe pancreatitits may be complicated by the development of 'walled-off pancreatic necrosis' (WOPN), which is characterised by a mixture of solid components and fluids on imaging studies as a consequence of organised pancreatic tissue necrosis.
Ramia Ángel, José Manuel   +5 more
openaire   +2 more sources

Therapeutic Applications of Stimuli‐Based Release and Engineering of Extracellular Vesicles

open access: yesAdvanced NanoBiomed Research, EarlyView.
This review summarizes the effects of endogenous and exogenous stimuli, their effects on the natural release of extracellular vesicles, as well as their uptake and release. It also gives an overview of stimuli‐responsive EVs and their therapeutic applications. Extracellular vesicles (EVs), nano‐ to microsized lipid bilayer membrane‐bound particles, are
Gloria Kemunto, Kristen Dellinger
wiley   +1 more source

Features of Ultrasonographic Anatomy and Manifestations of Local Complications in Acute Necrotizing Pancreatitis

open access: yesИнновационная медицина Кубани
Relevance: Diagnosing pancreatic necrosis and its complications is challenging despite the widespread use of state-of-the-art highprecision imaging methods in routine practice.Objective: To determine topographic features of local complications of ...
Olga A. Tseneva   +6 more
doaj   +1 more source

Spatial Cell Death and Oxidative Stress Dynamics in Gas Plasma‐Treated Tumor Tissues

open access: yesAdvanced NanoBiomed Research, EarlyView.
Schematic representation of the four experimental models to study tissue penetration and oxidation. Four tissue models were used. Human pancreatic cancer cells were grown on the chorioallantois membrane of chicken embryos and gas plasma‐treated in ovo, murine colorectal tumor tissue was gas plasma‐exposed ex vivo, murine squamous cell carcinoma cells ...
Anke Schmidt   +4 more
wiley   +1 more source

Clinical models of necrotizing pancreatitis - the way for optimal choise of surgery

open access: yesКубанский научный медицинский вестник, 2014
523 patients with necrotizing pancreatitis (2006-2013) were retrospectively analyzed. We compared results of the CT data, intraoperative locat-dock, the results of histological examination of biopsy material of 77 cases of necrotizing pacreatitis ...
A. V. Shabunin, A. Y. Lukin
doaj  

Surgical treatment for acute pancreatitis and pancreatic necrosis

open access: yesFolia Morphologica
Pancreatitis, considered by clinicians to be one of the most serious abdominal disorders, is a life-threatening disease resulting in numerous complications if not diagnosed early or treated with special care. Management is based on supportive care, including rehydration, pain control, continuous monitoring of vital signs and assessment of organ ...
Julia, Walkowska   +7 more
openaire   +2 more sources

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