Results 221 to 230 of about 176,259 (332)

CLDN18.2 CAR‐derived Extracellular Vesicle Immunotherapy Improves Outcome in Murine Pancreatic Cancer

Advanced Healthcare Materials, EarlyView.
CLDN18.2 CAR‐T cell‐derived small extracellular vesicles (CAR‐sEVs) display potent cytotoxicity and prolong survival in preclinical pancreatic cancer models. They contain functional CAR proteins and granzyme B, exhibit antigen specificity, and effectively target tumor cells while sparing healthy cells.
Yue Qing, Ke Jiang, Hua Jiang, Yaru Zhao, Chu‐Hu Lai, Alexandra Aicher, Zonghai Li, Christopher Heeschen   +7 more
wiley   +1 more source

β‐1,3 Glucan Microparticles & Nanoparticles: Fabrication Methods & Applications in Immunomodulation & Targeted Drug Delivery

Advanced Healthcare Materials, EarlyView.
Beta‐glucans have gained significant attention as an immunomodulatory biomaterial with cell‐targeting capabilities. This review comprehensively outlines the design and fabrication methods for producing beta‐glucan particles at both the micro and nanoscale and their applications in immune cell targeting, immunomodulation, and drug delivery ...
Nate Dowdall, Todd Hoare
wiley   +1 more source

Comprehensive genomic and transcriptomic characterization of high-grade gastro-entero-pancreatic neoplasms. [PDF]

Br J Cancer
Angerilli V, Sabella G, Simbolo M, Lagano V, Centonze G, Gentili M, Mangogna A, Coppa J, Munari G, Businello G, Borga C, Schiavi F, Pusceddu S, Leporati R, Oldani S, Fassan M, Milione M.   +16 more
europepmc   +1 more source

Gastric Duplication Cysts Expressing Carcinoembryonic Antigen Mimicking Cystic Pancreatic Neoplasms in Two Adults

, 2008
Jeffrey S. Johnston, Grayson H. Wheatley, Hosam F. El Sayed, William B. Marsh, E. Christopher Ellison, Mark Bloomston   +5 more
openalex   +1 more source

Mesenteric venous collateral vessels mimicking cystic pancreatic neoplasm [PDF]

, 2010
Baskaran Sundaram, Jessica B. Robbins, Mark Zeglis, James M. Scheiman, Diane M. Simeone, Isaac R. Francis   +5 more
openalex   +1 more source

Multi‐material Volumetric Bioprinting and Plug‐and‐play Suspension Bath Biofabrication via Bioresin Molecular Weight Tuning and via Multiwavelength Alignment Optics

Advanced Materials, Volume 37, Issue 13, April 2, 2025.
Multimaterial volumetric and embedded extrusion bioprinting of complex cell‐laden architectures is enabled by unravelling the interplay between molecular weight and degree of functionalization in gelatin‐based bioresins. Tomographic light‐responsive support baths for suspended printing can be easily generated from single component materials.
Davide Ribezzi, Jan‐Philip Zegwaart, Thomas Van Gansbeke, Aitor Tejo‐Otero, Sammy Florczak, Joska Aerts, Paul Delrot, Andreas Hierholzer, Martin Fussenegger, Jos Malda, Jos Olijve, Riccardo Levato   +11 more
wiley   +1 more source

Rational Design of Metal–Organic Frameworks for Pancreatic Cancer Therapy: from Machine Learning Screening to In Vivo Efficacy

Advanced Materials, EarlyView.
This work explores the MOF landscape to select a single, optimal candidate for successfully delivering cancer drugs (gemcitabine, paclitaxel, SN‐38) into tough pancreatic tumors. Machine learning and simulations guide this search, demonstrating colloidal stability, excellent biocompatibility, cellular uptake, and sustained release.
Francesca Melle, Dhruv Menon, João Conniot, Jon Ostolaza‐Paraiso, Sergio Mercado, Jhenifer Oliveira, Xu Chen, Bárbara B. Mendes, João Conde, David Fairen‐Jimenez   +9 more
wiley   +1 more source

Pancreatic intraductal papillary mucinous neoplasm with concomitant heterotopic pancreatic cystic neoplasia of the stomach: a case report and review of the literature [PDF]

, 2010
Dimitrios Tsapralis, Alexandros Charalabopoulos, Eva Karamitopoulou, Dimitriοs Schizas, Alexandros Charalabopoulos, Theodore Liakakos, Anastasios Macheras   +6 more
openalex   +1 more source

Engineering CAR‐T Therapeutics for Enhanced Solid Tumor Targeting

Advanced Materials, EarlyView.
CART cell therapy has proven effective for blood cancers but struggles with solid tumors due to diverse antigens and complex environments. Recent efforts focus on improving CAR design and validation platforms. Advances in protein engineering, machine learning, and organoid systems aim to enhance CAR‐T therapy against solid tumors.
Danqing Zhu, Won Joon Kim, Hyunjin Lee, Xiaoping Bao, Pilnam Kim   +4 more
wiley   +1 more source

GLYCOSYLATION VARIANTS ON MUCINS AS CANDIDATE MARKERS FOR THE DIAGNOSIS OF PANCREATIC CYSTIC NEOPLASMS

, 2008
Brian B. Haab, Andrew P. Porter, M Schmidt, C. J. Lee, Dawn Barnes, Diane M. Simeone   +5 more
openalex   +1 more source