Results 11 to 20 of about 39,716 (234)

Imaging of Pancreatic Neuroendocrine Neoplasms [PDF]

International Journal of Environmental Research and Public Health, 2021
Pancreatic neuroendocrine neoplasms (panNENs) represent the second most common pancreatic tumors. They are a heterogeneous group of neoplasms with varying clinical expression and biological behavior, from indolent to aggressive ones. PanNENs can be functioning or non-functioning in accordance with their ability or not to produce metabolically active ...
Giuditta Chiti, Giulia Grazzini, Diletta Cozzi   +2 more
exaly   +5 more sources

Surgical management of pancreatic neuroendocrine neoplasms

Laparoscopic, Endoscopic and Robotic Surgery, 2023
Pancreatic neuroendocrine neoplasms are a rare and complex group of neoplastic lesions that develop from pancreatic islet cells. Their incidence has dramatically increased during the last two decades. Due to its complex nature and pathophysiological behaviour, surgical management continues to evolve.
Piero Alberti, David Martin, Georgios Gemenetzis, Rowan Parks   +3 more
openaire   +5 more sources

Imaging presentation of pancreatic neuroendocrine neoplasms [PDF]

Insights into Imaging, 2018
Pancreatic neuroendocrine neoplasms (P-NENs) are the second most common solid pancreatic neoplasms. P-NENs have a wide range of imaging features presentations and they can be detected with typical and atypical imaging presentations. Typical and atypical appearances can be explained by pathologic correlations. P-NENs are generally hypervascular lesions,
Ciaravino V, De Robertis R, Tinazzi Martini P, Cardobi N, Cingarlini S, Amodio A, Landoni L, Capelli P, D'Onofrio M   +8 more
openaire   +5 more sources

Diabetes in Patients With Pancreatic Neuroendocrine Neoplasms [PDF]

Frontiers in Endocrinology, 2020
ObjectiveDiabetes mellitus (DM) is probably a risk factor for pancreatic neuroendocrine neoplasms (PNENs). However, the prevalence of DM in PNEN patients remains inconclusive. In the present study we observed the prevalence of DM and possible risk factors in PNEN patients.MethodsAfter excluding those with insulinoma, a total of 197 patients with PNENs ...
Xiaoling Zhuge, Yajie Wang, Xiao Chen, Chuangen Guo   +3 more
openaire   +4 more sources

Proteotranscriptomic classification and characterization of pancreatic neuroendocrine neoplasms [PDF]

Cell Reports, 2021
Pancreatic neuroendocrine neoplasms (PNENs) are biologically and clinically heterogeneous. Here, we use a multi-omics approach to uncover the molecular factors underlying this heterogeneity. Transcriptomic analysis of 84 PNEN specimens, drawn from two cohorts, is substantiated with proteomic profiling and identifies four subgroups: Proliferative, PDX1 ...
Kevin C Yang, Steve E Kalloger, Christopher Rushton   +2 more
exaly   +3 more sources

Determinants of incidence trends in pancreatic neuroendocrine neoplasms. [PDF]

J Neuroendocrinol
Abstract The incidence of pancreatic neuroendocrine neoplasms (NENs) is rising; whether this reflects a true increase in disease occurrence or improved detection remains uncertain. We conducted a retrospective, population‐based study using data from the Surveillance, Epidemiology, and End Results (SEER) Program ...
Lamberti G, Andrini E, Di Odoardo A, Zappi A, Ricci C, Campana D.   +5 more
europepmc   +4 more sources

An Insight on Functioning Pancreatic Neuroendocrine Neoplasms

Biomedicines, 2023
Pancreatic neuroendocrine neoplasms (PanNENs) are rare neoplasms arising from islets of the Langerhans in the pancreas. They can be divided into two groups, based on peptide hormone secretion, functioning and nonfunctioning PanNENs. The first group is characterized by different secreted peptides causing specific syndromes and is further classified into
Bevere, Michele, Gkountakos, Anastasios, Martelli, Filippo Maria, Scarpa, Aldo, Luchini, Claudio, Simbolo, Michele   +5 more
openaire   +4 more sources

Surgical management of pancreatic neuroendocrine neoplasms

Annals of Saudi Medicine, 2014
Pancreatic neuroendocrine neoplasms are relatively rare entities, representing approximately 1% to 2% of all pancreatic tumors. Owing to their rarity as well as their relatively indolent natural history, treatment approaches are not yet standardized. A formal pancreatic resection is usually mandatory for large and localized sporadic pancreatic tumors ...
Maurizi Angela, Tamburrino Domenico, Pandolfi Silvia, FALCONI , MASSIMO, CRIPPA, STEFANO, PARTELLI, STEFANO   +5 more
openaire   +5 more sources

Management of Functional Pancreatic Neuroendocrine Neoplasms

Current Treatment Options in Oncology, 2023
Opinion statementFunctional pancreatic neuroendocrine neoplasms (pNENs) are rare and heterogeneous diseases in terms of both clinical and pathological aspects. These tumors secrete hormones or peptides, which may cause a wide variety of symptoms related to a clinical syndrome.
Magi, Ludovica, Marasco, Matteo, Rinzivillo, Maria, Faggiano, Antongiulio, Panzuto, Francesco   +4 more
openaire   +2 more sources

Total Pancreatectomy for Multicentric Cystic Neuroendocrine Tumor of the Pancreas: A Case Report

Diagnostics, 2022
Pancreatic neuroendocrine tumors (PNETs) are uncommon pancreatic neoplasms with malignant potential, heterogeneous clinical behavior, as well as imaging appearance.
Milica Mitrovic-Jovanovic, Nikica Grubor, Stefan Milosevic, Aleksandra Jankovic, Katarina Stosic, Slavenko Ostojic, Aleksandar Ninic, Marjan Micev, Jelena Djokic Kovac   +8 more
doaj   +1 more source