Pancreatic Neuroendocrine Neoplasms: Landscape and Horizon [PDF]
Context.— Since the initial description of pancreatic endocrine physiology and the recognition of islet cell tumors in the 1800s, there have been noteworthy advances in the pathobiology of pancreatic neuroendocrine neoplasms (PanNENs), and definition of the important distinction between well-differentiated ...
openaire +2 more sources
Consensus on the clinical diagnosis and treatment of grade 3 pancreatic neuroendocrine tumors
The World Health Organization (WHO) 2017 classifications for neuroendocrine neoplasms (NENs) subdivided grade 3 pancreatic neuroendocrine neoplasms (pNENs) into G3 well-differentiated pancreatic neuroendocrine tumors (G3 pNETs) and poorly differentiated ...
Jie Chen +22 more
doaj +1 more source
Background Mixed neuroendocrine-non-neuroendocrine neoplasms (MiNEN) of the pancreas are extremely rare. Their pathogenesis and molecular landscape are largely unknown.
Jingci Chen +3 more
doaj +1 more source
Gastroenteropancreatic neuroendocrine tumours – an overview
Neuroendocrine neoplasms (NENs) belong to a group of various tumours that can arise on many internal organs. Among NENs a large class of gastroenteropancreatic neuroendocrine tumours (GEP-NETs) can be distinguished, which comprise neoplasms arising from ...
Karol Maciejewski +5 more
doaj +1 more source
A Review on Endoscopic Ultrasound-Guided Radiofrequency Ablation (EUS-RFA) of Pancreatic Lesions
The morbidity associated with pancreatectomies limits surgical options for high-risk patients with pancreatic neoplasms that warrant resection. Endoscopic ultrasound-guided radiofrequency ablation (EUS-RFA) offers a minimally invasive and potentially ...
Fred G. Karaisz +4 more
doaj +1 more source
Added value of multifrequency magnetic resonance elastography in predicting pathological grading of pancreatic neuroendocrine neoplasms. [PDF]
Objectives To prospectively investigate the pancreatic stiffness (c) and fluidity (φ) of pancreatic neuroendocrine neoplasms (pNENs), measured using multifrequency magnetic resonance elastography (MRE), and evaluate their performance in predicting pNENs ...
Yuan J +9 more
europepmc +2 more sources
Reconsideration of operative indications in pancreatic neuroendocrine neoplasms
Abstract Background The incidence of pancreatic neuroendocrine neoplasm (PNEN) has been increasing. Resection is typically indicated for PNEN, regardless of its size; however, the indications for its resection are controversial.
Kodai Abe +9 more
openaire +3 more sources
Outcome of surgery for pancreatic neuroendocrine neoplasms
Abstract Background The incidence of pancreatic neuroendocrine neoplasms (pNEN) is increasing. This study aimed to evaluate predictors of overall survival and the indication for surgery. Methods Data collected between October 2001 and
L, Fischer +8 more
openaire +2 more sources
Medical Treatment of Advanced Pancreatic Neuroendocrine Neoplasms [PDF]
Pancreatic neuroendocrine neoplasms (panNENs) are relatively rare but their incidence has increased almost sevenfold over the last four decades. Neuroendocrine neoplasms are classified according to their histologic differentiation and their grade. Their grade is based on their Ki-67 proliferation index and mitotic index.
Lola-Jade Palmieri +6 more
openaire +2 more sources
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source

