Results 41 to 50 of about 393,422 (164)

Case Report: Pancreatic amphicrine-like carcinoma with acinar differentiation harboring a KANK4-RAF1 gene fusion

Pathology and Oncology Research
Pancreatic amphicrine-like carcinoma (ALC) is an exceptionally rare neoplasm characterized by simultaneous exocrine and endocrine differentiation within the same tumour cells.
Sabrina Kammerer, Peter Bode, Heide Schreiber, Guacimara Ortega Sanchez   +3 more
doaj   +1 more source

Molecular pathology of pancreatic neuroendocrine neoplasms

, 2015
Pancreatic neuroendocrine neoplasms (PanNENs) are a heterogeneous group of lesions exhibiting different genetic and epigenetic characteristics that affect the biological behavior of the tumor.
Daniela Furlan, FURLAN, DANIELA
core   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

A rare pancreatic neoplasm in a 40‐year‐old male patient

Clinical Case Reports, 2023
Key Clinical Message The differential diagnoses of solid pseudopapillary neoplasm of the pancreas include cystic pancreatic neuroendocrine tumor, acinar cell carcinoma, and pancreatoblastoma.
Faten Limaiem, Mohamed Hajri
doaj   +1 more source

An Insight on Functioning Pancreatic Neuroendocrine Neoplasms

Biomedicines, 2023
Pancreatic neuroendocrine neoplasms (PanNENs) are rare neoplasms arising from islets of the Langerhans in the pancreas. They can be divided into two groups, based on peptide hormone secretion, functioning and nonfunctioning PanNENs.
Michele Bevere, Anastasios Gkountakos, Filippo Maria Martelli, Aldo Scarpa, Claudio Luchini, Michele Simbolo   +5 more
doaj   +1 more source

scTIDE: Deciphering Critical Transitions Through Cell‐Perturbed Manifold Graphs and Optimal Transport Conditional Flow Matching

Advanced Science, EarlyView.
scTIDE identifies single‐cell tipping points by combining manifold‐based graph representations with optimal‐transport conditional flow matching, which preserves intrinsic topology and models distributional dynamics. It supports critical‐transition detection at individual‐cell resolution, prediction of unseen cells, and dimensionality reduction and ...
Jiayuan Zhong, Bowen Niu, Yongbo Yu, Shiyang Nie, Xuerong Gu, Pei Chen, Rui Liu   +6 more
wiley   +1 more source

Mesenteric Variceal Haemorrhage and Ectopic Cushing’s Syndrome as Presenting Features of a Pancreatic Neuroendocrine Tumour Recurrence

Case Reports in Gastroenterology, 2021
Pancreatic neuroendocrine tumours can have varied and complex presentations. Whilst hormone hypersecretion often induces characteristic clinical syndromes, non-specific symptoms may arise due to localized tumour effects.
Scott Weerasuriya, Kieran Palmer, Stephen Gregory, Benjamin C. Whitelaw, Elisa Gonzalez, Rajaventhan Srirajaskanthan   +5 more
doaj   +1 more source

Surgical Therapy of Pancreatic Neuroendocrine Neoplasms

, 2015
Pancreatic neuroendocrine tumors are relatively rare entities, which consist of single or multiple benign or malignant neoplasms. It will be shown that in 10-20 % of patients, they can be associated with inherited syndromes, such as multiple endocrine ...
Muffatti F., Francesca Muffatti, Sara Nobile, Partelli S., Nobile S., Falconi M., Angela Maurizi, Stefano Partelli, Massimo Falconi, Maurizi A.   +9 more
core   +1 more source

Review of Gastrointestinal Capsule Robots: Materials, Actuation, Diagnostics, and Therapeutics

Advanced Science, EarlyView.
This review examines gastrointestinal capsule robots through a systems engineering lens, covering shell materials, actuation and localization strategies, diagnostic modalities, therapeutic interventions, and commercialization status. By mapping the complete technological chain from fabrication to clinical deployment, this work identifies critical gaps ...
Zengsheng Li, Zhongguo Ren, Yiliang Lin, Xianfeng Xia, Tianlong Li, Kai Fung Chan, Philip Wai Yan Chiu, Wei Peng Yong, Mengmeng Sun   +8 more
wiley   +1 more source