Results 51 to 60 of about 393,422 (164)

Real-World Effectiveness of Capecitabine and Temozolomide Across Endocrine and Neuroendocrine Neoplasm Subtypes (ENENs): A Population-Based Cohort Study from Alberta, Canada (2011–2021)

Current Oncology
Capecitabine plus temozolomide (CAPTEM) improves progression-free survival (PFS) in pancreatic endocrine and neuroendocrine neoplasms (PNENs), yet its real-world effectiveness across other endocrine and neuroendocrine neoplasm (ENEN) subtypes remains ...
Alda Aleksi, Kaiden D. Jobin, Malek B. Hannouf, Patrik Husi, Heather Halperin, Chris White-Gloria, Tasnima Abedin, Dean Ruether   +7 more
doaj   +1 more source

Rare breast and subcutaneous metastases from pancreatic neuroendocrine tumor: a case report

World Journal of Surgical Oncology, 2019
Background Neuroendocrine tumors are a group of rare neoplasms, and the pancreatic neuroendocrine tumors (PNETs) represent only 1–2% of all pancreatic malignant tumors.
Dorotea Bosco, Salvatore Perrotti, Corrado Spatola, Giada Maria Vecchio, Rosalia Latino, Antonio Di Cataldo   +5 more
doaj   +1 more source

Discovery and Optimization of AMT‐676, a CDH17‐Targeting ADC for the Treatment of Advanced Gastrointestinal Cancers

Advanced Science, EarlyView.
AMT‐676 is a novel antibody‐drug conjugate targeting CDH17, an adhesion molecule uniquely exposed on gastrointestinal tumor surfaces. Engineered with an optimized exatecan payload, it demonstrates profound tumor regression and a robust bystander effect across diverse preclinical models.
Ying‐nan Wang, Dan‐yun Ruan, Jing Shi, Yue Huang, Hui Sheng, Ya‐ling Huang, Linjie Ma, Lijun Wang, Caiwei Chen, Yixuan Wang, Yue Zhang, Yi Shen, Qing Zhang, Jianjian Zhang, Yanfang Tang, Jin‐ling Zhang, Jia‐jia Hu, Chen‐yi Wu, Jia‐ying Chen, Xun Meng, Shu‐Hui Liu, Feng Wang   +21 more
wiley   +1 more source

Endoscopic Ultrasound-Guided Ablation of Focal Pancreatic Lesions: The GRUPUGE Perspective

GE: Portuguese Journal of Gastroenterology, 2020
Focal pancreatic lesions include a heterogeneous group of solid and cystic lesions, with different natures and variable clinical, imagiological, and pathological characteristics.
Miguel Bispo, Ana Caldeira, Sílvia Leite, Susana Marques, Teresa Moreira, Pedro Moutinho-Ribeiro, Nuno Nunes   +6 more
doaj   +1 more source

Pancreatic neuroendocrine neoplasms : from genetics to everolimus resistance [PDF]

, 2021
Pancreatic neuroendocrine neoplasms are rare tumors of which the genetic constitution is not fully understood. In addition, resistance against everolimus, a frequently used treatment modality, forms a clinical challenge in these tumors.
Vandamme, TAL, Vandamme, T.A.L. (Timon), Vandamme, Timon   +2 more
core   +1 more source

A rare presentation of an ACTH‐producing high‐grade large cell neuroendocrine carcinoma with Cushing’s syndrome

Clinical Case Reports, 2021
High‐grade neuroendocrine tumors (HGNET) are rare neoplasms composed of neural and hormonal with only around 42 cases reported in the last 20 years1.
Francis Essien, Christine Persaud, David Dado, Rina Eden, Joshua Tate, George Shahin   +5 more
doaj   +1 more source

Pancreatic neuroendocrine tumours: a comparison of cytological classification systems. [PDF]

Aims: Cytological classification systems provide a standardised interpretation framework for reporting cytological specimens. Three well-known classification systems can be applied when reporting pancreatic cytology.
Hanks, Matthew, Zaitoun, Abed M, Sajid, Saira, Lobo, Dileep N, Bancu, Andrei, Khan, Marium, Ackroyd, Lauren   +6 more
core   +1 more source

Advanced Imaging of Pancreatic Neoplasms

, 2022
Imaging has a pivotal role in pancreatic neoplasms, ranging from diagnosis to treatment monitor. It is crucial, especially for pancreatic ductal adenocarcinoma (PDAC), to obtain an early diagnosis, since the therapeutic approach is mainly surgical and ...
Cardobi N., De Robertis R., D'Onofrio M.
core   +1 more source

Multidisciplinary treatment of pancreatic neuroendocrine neoplasm with portal vein thrombosis and multiple liver metastases by minimally invasive surgical and neoadjuvant therapy

Journal of Pancreatology
The treatment of patients with pancreatic neuroendocrine neoplasms accompanied by metastasis is complex and highly individualized. This article reports a 43-year-old male patient diagnosed with a neuroendocrine tumor on the pancreatic tail combined with ...
Hao Chen, Wenhao Luo, Xianze Wang, Zhe Cao, Xianlin Han   +4 more
doaj   +1 more source

Surgical management of pancreatic neuroendocrine neoplasms

Annals of Saudi Medicine, 2014
Pancreatic neuroendocrine neoplasms are relatively rare entities, representing approximately 1% to 2% of all pancreatic tumors. Owing to their rarity as well as their relatively indolent natural history, treatment approaches are not yet standardized.
Stefano Partelli, Angela Maurizi, Domenico Tamburrino, Stefano Crippa, Silvia Pandolfi, Massimo Falconi   +5 more
doaj   +1 more source