Results 1 to 10 of about 1,031,133 (262)
Liver metastasis or a pseudocyst? A rare presentation of leiomyosarcoma’s metastasis in the liver
Contemporary Oncology, 2023 Gastrointestinal neoplasms most commonly metastasize to the liver, where they are typically found as solid and hypervascular lesions. Here, we describe a case of a 44-year-old man with a leiomyosarcoma of the rectum, who at the time of diagnosis ...
Adrian Bednarek +7 more
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Liver Metastasis in Cancer: Molecular Mechanisms and Management
MedCommLiver metastasis is a leading cause of mortality from malignant tumors and significantly impairs the efficacy of therapeutic interventions. In recent years, both preclinical and clinical research have made significant progress in understanding the ...
Wenchao Xu +5 more
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Comprehensive analysis of complement-associated molecular features in hepatocellular carcinoma
Acta Biochimica et Biophysica Sinica, 2022 The complement cascade plays a “complementing” role in human immunity. However, the potential roles of complement system in impacting molecular and clinical features of hepatocellular carcinoma (HCC) remain unclear.
Huang Run +13 more
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Journal for ImmunoTherapy of Cancer, 2021 Background Hepatocellular carcinoma (HCC) is characterized by inflammation and immunopathogenesis. Accumulating evidence has shown that the cystathionine β-synthase/hydrogen sulfide (CBS/H2S) axis is involved in the regulation of inflammation.
Jian Zhou +15 more
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Cell Discovery, 2023 Mixed lineage kinase domain-like (MLKL) is widely accepted as an executioner of necroptosis, in which MLKL mediates necroptotic signaling and triggers cell death in a receptor-interacting protein kinase 3 (RIPK3)-dependent manner.
Xifei Jiang +24 more
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Current landscape and perspective of oncolytic viruses and their combination therapies
Translational Oncology, 2022 Oncolytic virotherapy has become an important strategy in cancer immunotherapy. Oncolytic virus (OV) can reshape the tumor microenvironment (TME) through its replication-mediated oncolysis and transgene-produced anticancer effect, inducing an antitumor ...
Yinghan Su, Changqing Su, Lunxiu Qin
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Molecular mechanism and potential therapeutic targets of liver metastasis from gastric cancer
Frontiers in Oncology, 2022 Gastric cancer (GC) is characterized by high invasion and poor prognosis. The occurrence of liver metastasis seriously affects advanced GC prognosis. In recent years, great progress has been made in the field of GC liver metastasis.
Difeng Li +4 more
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World Journal of Surgical Oncology, 2023 Background Liver stiffness relates to more advanced tumor status and poor outcomes in primary liver cancer, while its prognostic role in pancreatic cancer with liver metastasis is unclear.
Shu Dong +5 more
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The emerging roles of non-coding competing endogenous RNA in hepatocellular carcinoma
Cancer Cell International, 2020 Accumulating evidence has emerged revealing that noncoding RNAs (ncRNAs) play essential roles in the occurrence and development of hepatocellular carcinoma (HCC). However, the complicated regulatory interactions among various ncRNAs in the development of
Gang Xu +6 more
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Journal of Experimental & Clinical Cancer Research, 2023 Background The most common site of metastasis in colorectal cancer (CRC) is the liver and liver metastases occur in more than 50% of patients during diagnosis or treatment.
Guangshun Sun +12 more
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