Liver Extracellular Matrix in Colorectal Liver Metastasis
The liver is the most common site of metastasis of colorectal cancer (CRC), and colorectal liver metastasis is one of the major causes of CRC-related deaths worldwide. The tumor microenvironment, particularly the extracellular matrix (ECM), plays a critical role in CRC metastasis and chemoresistance.
Morabito, Marika +7 more
openaire +3 more sources
Liver metastasis mimicking an abscess
Hepatic metastases from carcinoid tumours are typically solid, hypervascular lesions on imaging. The cystic form, mimicking an abscess, is extremely rare. We report a case of a 48-year-old female presenting with a large hepatic mass that was diagnosed as a hepatic abscess, but the ultrasound-guided biopsy showed well-differentiated grade 1 ...
Kaoutar Imrani +4 more
openaire +2 more sources
Background Gallbladder cancer (GBC) with liver metastasis is considered unresectable. However, there have been infrequent reports of long-term survival in patients with GBC and liver metastases.
Ryota Higuchi +10 more
doaj +1 more source
Transplantation for colorectal liver metastasis
Purpose of review Liver transplantation has emerged as a possible treatment for selected patients with nonresectable colorectal liver metastasis, but controversy still exists regarding optimal selection criteria and acceptable outcomes.
Line, Pål-Dag, Dueland, Svein
openaire +2 more sources
Risk factors and prognosis of liver metastasis in gallbladder cancer patients: A SEER-based study
BackgroundLiver metastasis is a common complication in gallbladder cancer (GBC). We design this study to develop models for predicting the development of liver metastasis in GBC patients and evaluate the risk of mortality in these patients with liver ...
Cheng Fang +6 more
doaj +1 more source
Portal Vein Clamp and Subsequent Blood Reflow Enhance Liver Metastasis of Colon ACL-15 Cells Administered Intrasplenically in F344/DU Rats [PDF]
We explored the relationship between transient portal vein clamping (TPVC)-induced adhesion molecule expression in the liver and liver metastasis. TPVC was achieved by clamping the portal vein of male F344/ DU rats for 15 min.For the investigation of ...
麻沼, 和彦, 山本, 誠
core +1 more source
Colorectal Liver Metastasis: Can Cytokines Make the Difference?
Colorectal cancer (CRC) is the third leading cause of cancer-related death worldwide. Metastasis is the prime driver of CRC-related mortality, and the liver is the organ most frequently involved.
Gianluigi Giannelli +2 more
core +1 more source
Risk Factors of Early Liver Metastasis for Pancreatic Ductal Adenocarcinoma after Radical Resection
Background. Liver metastasis arises in many postoperative patients with PDAC, occurring in the early stage appears to lead to a very poor prognosis. Objective.
Jingshu Tong +5 more
doaj +1 more source
First human study in treatment of unresectable liver metastases from colorectal cancer with irinotecan-loaded beads (DEBIRI) [PDF]
The objective of this pilot clinical study was to assess the safety, technical feasibility, pharmacokinetic (PK) profile and tumour response of DC Bead™ with irinotecan (DEBIRI™) delivered by intra-arterial embolisation for the treatment of metastatic ...
Hammerstingl, Renate Maria +6 more
core +1 more source
A Long Non-coding RNA Signature to Improve Prognostic Prediction of Pancreatic Ductal Adenocarcinoma
Background: Pancreatic ductal adenocarcinoma (PDAC) remains one of the most aggressive solid malignant tumors worldwide. Increasing investigations demonstrate that long non-coding RNAs (lncRNAs) expression is abnormally dysregulated in cancers.
Chenhao Zhou +21 more
doaj +1 more source

