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Neuroendocrine Pancreatic Tumors

, 2018
The incidence of PNETs has been increasing, due to the increasing use of cross-sectional imaging. They are a complex and heterogeneous group of neoplasms which can present as single or multiple lesions, sporadic or associated to a genetic syndrome.
Marco Miotto, Giovanni Marchegiani, Giulia Zamboni   +2 more
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Pancreatic Neuroendocrine Tumors

Surgical Pathology Clinics, 2016
Pancreatic neuroendocrine neoplasms include well-differentiated pancreatic neuroendocrine tumors (PanNETs) and neuroendocrine carcinomas (NECs) with well-differentiated PanNETs accounting for most cases. Other pancreatic primaries and metastatic carcinomas from other sites can mimic pancreatic neuroendocrine neoplasms.
Safia N, Salaria, Chanjuan, Shi
  +5 more sources

Pancreatic neuroendocrine tumors

Disease-a-Month, 2013
Pancreatic neuroendocrine tumors (PNETs) have an incidence of approximately 1 per 100,000 individuals per year, and account for 1–2% of all pancreatic tumors. The annual incidence in the United States is about 3.65 per 100,000 population. Although they may manifest at any age, they most often occur in the fourth to sixth decades of life. Most PNETs are
Thiruvengadam, Muniraj, Sabitha, Vignesh, Shilpa, Shetty, Sudha, Thiruvengadam, Harry R, Aslanian   +4 more
  +6 more sources

Pancreatic neuroendocrine tumors

Indian Journal of Gastroenterology, 2012
Pancreatic neuroendocrine tumors (pancreatic NETs) are rare, low- to intermediate-grade neoplasms thought to arise from the pancreatic islets. Recent advances in pathology and our understanding of the biological behavior of this group of tumors has resulted in changes in their nomenclature and how we treat them.
Shailesh V, Shrikhande, Bhawna, Sirohi, Mahesh, Goel, Savio G, Barreto   +3 more
openaire   +3 more sources

Genetics of Pancreatic Neuroendocrine Tumors

Hematology/Oncology Clinics of North America, 2022
Pancreatic neuroendocrine tumors (pNETs) represent a relatively rare disease; however, the incidence has been increasing during the last 2 decades. Next generation sequencing has greatly increased our understanding of driver mutations in pNETs. Sporadic pNETs have consistently presented with mutations in MEN1, DAXX/ATRX, and genes related to the ...
Chirayu, Mohindroo, Florencia, McAllister, Ana, De Jesus-Acosta   +2 more
openaire   +2 more sources

Pancreatic Neuroendocrine Tumors

Endocrine Research, 2011
Pancreatic neuroendocrine tumors (PNETs) are rare neoplasms representing
Elizabeth, Batcher, Paul, Madaj, Andrew G, Gianoukakis   +2 more
openaire   +2 more sources

Radiotherapy for Pancreatic Neuroendocrine Tumors

International Journal of Radiation Oncology*Biology*Physics, 2009
Pancreatic neuroendocrine tumors (PNTs) are rare malignant neoplasms considered to be resistant to radiotherapy (RT), although data on efficacy are scarce. We reviewed our institutional experience to further delineate the role of RT for patients with PNTs.Between 1986 and 2006, 36 patients with PNTs were treated with RT to 49 sites.
Joseph N, Contessa, Kent A, Griffith, Elizabeth, Wolff, William, Ensminger, Mark, Zalupski, Theodore S, Lawrence, Edgar, Ben-Josef   +6 more
openaire   +2 more sources

Nonfunctional Pancreatic Neuroendocrine Tumors

Surgical Clinics of North America, 2014
Pancreatic neuroendocrine tumors are a group of rare, heterogeneous neoplasms that have been increasing in incidence the past few decades largely because of the diagnosis of pancreatic incidentalomas on cross-sectional imaging. Although these tumors are classically associated with clinical syndromes that result from excess secretion of particular ...
Jennifer H, Kuo, James A, Lee, John A, Chabot   +2 more
openaire   +2 more sources

Sunitinib in pancreatic neuroendocrine tumors

Targeted Oncology, 2012
Sunitinib is an oral multitarget tyrosine kinase inhibitor with potent antiangiogenic properties. Preclinical data have demonstrated that pancreatic neuroendocrine tumors depend on vascular endothelial growth factor receptors and platelet growth factor receptors-signaling pathways for tumor angiogenesis.
Eric, Raymond, Pascal, Hammel, Chantal, Dreyer, Christian, Maatescu, Olivia, Hentic, Philippe, Ruszniewski, Sandrine, Faivre   +6 more
openaire   +2 more sources

Pancreatic neuroendocrine tumors: a review

Future Oncology, 2015
Neuroendocrine tumors (NETs) are a rare and heterogeneous group of tumors with widely varying morphologies and behaviors. Due to their rarity and heterogeneity, progress in improving their treatment has been slow. However, in recent years there have been advances both in their characterization and in the available treatment options.
Kate, Young, Ridhima, Iyer, Daniel, Morganstein, Ian, Chau, David, Cunningham, Naureen, Starling   +5 more
openaire   +2 more sources