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Advancements in pancreatic neuroendocrine tumors
Expert Review of Gastroenterology & Hepatology, 2013Pancreatic neuroendocrine tumors (PanNETs) have increased in incidence in the USA over the last 20 years. Although PanNETs are often misconceived as being indolent tumors as they have a far more favorable prognosis over pancreatic adenocarcinoma, roughly 60-70% of patients have metastatic disease at the time of diagnosis due to presentation late in the
Miral R, Sadaria +2 more
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Medical Management of Pancreatic Neuroendocrine Tumors
The American Journal of Gastroenterology, 2008Pancreatic neuroendocrine tumors (PNET) are rare malignancies frequently diagnosed at a late stage, with symptoms related to bulky disease. Hormonal secretion, when responsible for symptoms, permits, on the other hand, early diagnosis of the disease. Surgery remains the cornerstone of therapeutic management.
Delaunoit, Thierry +4 more
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Non-Functioning Pancreatic Neuroendocrine Tumors
2015Nonfunctioning pancreatic neuroendocrine tumors are quite rare, representing 2 % of all pancreatic malignancies and 85 % of all pancreatic neuroendocrine tumors. They are classified based on the Ki-67 labeling index as “tumors” when Ki-67 is 20 %. On a molecular basis, they are different from pancreatic adenocarcinoma, expressing menin-1, death domain-
Anna Koumarianou, Nicola Fazio
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Pancreatic Neuroendocrine Tumors
2007Neuroendocrine tumors of the pancreas are uncommon neoplasms. They may occur as a sporadic lesion or as part of a genetic disease such as the multiple endocrine neoplasia type 1 (MEN-1) syndrome. Sporadic tumors usually arise as a single lesion, whereas those associated with familial disorders generally are multifocal.
Erik-Jan Wamsteker, James M. Scheiman
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Management of Pancreatic Neuroendocrine Tumors
Gastroenterology Clinics of North America, 2012Daniel M, Halperin, Matthew H, Kulke
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Cystic pancreatic neuroendocrine tumor
Gastrointestinal Endoscopy, 2010David L, Diehl +2 more
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Sunitinib and Everolimus in Pancreatic Neuroendocrine Tumors
Tumori Journal, 2012Giuseppe Procopio +2 more
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Advances in Pancreatic Neuroendocrine Tumor Treatment
New England Journal of Medicine, 2011Castellano, Daniel +2 more
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