Results 231 to 240 of about 62,032 (298)

Meta‐analysis of sotagliflozin, a dual sodium‐glucose‐cotransporter 1/2 inhibitor, for heart failure in type 2 diabetes

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 968-979, April 2025.
Abstract Sodium‐glucose co‐transporters (SGLTs) mediate sodium and glucose transport across cell membranes. SGLT2 inhibitors have a recognized place within heart failure (HF) guidelines. We evaluated the effect of sotagliflozin on HF and cardiovascular outcomes in participants with type 2 diabetes. Scopus, Medline, Embase and Central were searched from
Maria Anna Bantounou   +7 more
wiley   +1 more source

Duodenal Trauma: Mechanisms of Injury, Diagnosis, and Management. [PDF]

open access: yesJ Clin Med
Bova R   +6 more
europepmc   +1 more source

Lactate receptor HCAR1 in neonatal hypoxic–ischemic seizures

open access: yesEpilepsia, EarlyView.
Abstract Hydroxycarboxylic acid receptor 1 (HCAR1) is a G‐protein‐coupled lactate receptor expressed in the brain and plays a role in neuronal excitability and repair after injury. Hypoxic–ischemic encephalopathy (HIE) is the most common cause of brain injury and seizures in term neonates.
Jennifer Burnsed   +11 more
wiley   +1 more source

Cuproptosis‐Related Genes in Immune Infiltration and Diagnosis in Hepatitis B Virus‐Related Acute Liver Failure

open access: yesExploration, EarlyView.
The role of cuproptosis in HBV‐ALF was explored via bioinformatics and liver biopsy tissues. There are some crosstalks among cuproptosis, immune infiltration, and ferroptosis (The figure was created by Bio Render). ABSTRACT Hepatitis B virus (HBV) infection poses a significant challenge to global health, particularly in developing countries such as ...
Jingwen Deng   +10 more
wiley   +1 more source

Micro Pattern‐Based 3D Cell Culture Platform: An Overview of Technologies and Applications

open access: yesExploration, EarlyView.
Micro patterns are characterized as a coating of specific adhesion matrices on substrates to support cell growth. An overview of micropattern technology to regulate single cell morphology and fates, further focusing on the micro pattern‐based 3D cell culture platform used in the non‐tumor and tumor researches.
Xinglong Zhu   +8 more
wiley   +1 more source

Intestinal and multiple organ transplantation [PDF]

open access: yes, 2000
Abu-Elmagd, K   +6 more
core  

Immunosuppressive Microenvironment Reprogramming by Synergistic Sonodynamic Therapy of Phthalocyanine‐MOF Hybrids for Hepatocellular Carcinoma

open access: yesExploration, EarlyView.
Hepatocellular carcinoma presents a formidable clinical challenge, constructing a hypoxic and immunosuppressive microenvironment that renders conventional therapies largely ineffective. In response, we have developed Pc@Zr‐MOF, a phthalocyanine‐integrated metal‐organic framework hybrid engineered to penetrate this defensive barrier.
Han Wu   +13 more
wiley   +1 more source

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