Results 121 to 130 of about 191,039 (273)

Malignancies and immunoglobulin G4‐related disease

open access: yesRheumatology &Autoimmunity, EarlyView.
Immunoglobulin G4‐related disease (IgG4‐RD) is associated with increased cancer risk. Malignancies affect both IgG4‐RD involved organs, such as the lung, pancreas, bile duct, and prostate, and noninvolved organs, such as the gastrointestinal duct. B‐cell neoplasms constitute a proportion of the malignancies linked to this disease.
Jingna Li, Wen Zhang
wiley   +1 more source

Influencing factor analysis and clinical efficacy of early intervention in severe acute pancreatitis with persistent organ failure

open access: yesScientific Reports
This study aims to analyze the risk factors requiring early intervention in severe acute pancreatitis (SAP) patients with persistent organ failure and evaluate the clinical outcomes following treatment.
Minchun Bu   +6 more
doaj   +1 more source

Indirubin attenuates sepsis by targeting the EGFR/SRC/PI3K and NF-κB/MAPK signaling pathways in macrophages

open access: yesFrontiers in Pharmacology
BackgroundIsatidis Folium, a botanical drug widely used in traditional medicine, is known for its anti-inflammatory properties, including heat-clearing, detoxifying, and blood-cooling effects. Although its potential in sepsis treatment has been suggested,
Yancen Li   +9 more
doaj   +1 more source

Potential roles of antibodies with different classes in IgG4‐related diseases

open access: yesRheumatology &Autoimmunity, EarlyView.
This review discussed the common characteristics of different classes of antibodies and their potential corresponding unique mechanisms involved in immunoglobulin G4‐related disease. Abstract Immunoglobulin G4‐related disease (IgG4‐RD), first identified two decades ago, is an immune‐mediated pro‐inflammatory and profibrotic disease entity affecting ...
Ling Li   +6 more
wiley   +1 more source

Acute pancreatitis as a risk factor of chronic pancreatitis and pancreatic cancer. An overview

open access: yesBiomedical Papers
This is an overview of relation between acute and chronic pancreatitis and between acute pancreatitis and pancreatic cancer. Acute pancreatitis and recurrent acute pancreatitis are an etiological factor of chronic pancreatitis.
David Solil   +4 more
doaj   +1 more source

Nanoplasmonic Sensing of Heterogeneous Extracellular Vesicles: From Bulk to Single Vesicles

open access: yesSmall Methods, EarlyView.
Extracellular vesicles (EVs) are highly heterogeneous nanoscale blood biomarkers. With their tunable implementations, nanoplasmonic platforms can capture myriad vesicular information via scalable bulk analyses of EV biomarkers or high‐resolution single‐vesicle measurements.
Yan Zhang, Chao Wang, Huilin Shao
wiley   +1 more source

Elucidating the mechanism of stigmasterol in acute pancreatitis treatment: insights from network pharmacology and in vitro/in vivo experiments

open access: yesFrontiers in Pharmacology
IntroductionAcute pancreatitis (AP) is a severe inflammatory disease of the pancreas that could trigger a systemic inflammation and multi-organ dysfunction.
Xuanlin Zhao   +8 more
doaj   +1 more source

How to Survive and Succeed in the Design and Execution of a Collaborative Randomized Controlled Trial

open access: yesUnited European Gastroenterology Journal, EarlyView.
ABSTRACT This article guides the design and execution of successful collaborative randomized controlled trials (RCTs). Aimed at researchers looking to impact clinical practice, it highlights the advantages of RCTs over observational studies in driving clinical advancements.
Enrique de‐Madaria
wiley   +1 more source

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