Results 161 to 170 of about 472,362 (405)

Six questions on the construction of ontologies in biomedicine [PDF]

open access: yes, 2005
(Report assembled for the Workshop of the AMIA Working Group on Formal Biomedical Knowledge Representation in connection with AMIA Symposium, Washington DC, 2005.) Best practices in ontology building for biomedicine have been frequently ...
Burgun, A.   +11 more
core  

Classification of acute pancreatitis—2012: revision of the Atlanta classification and definitions by international consensus

open access: yesGut, 2012
P. Banks   +7 more
semanticscholar   +1 more source

Identification of Individuals at Increased Risk for Pancreatic Cancer in a Community-Based Cohort of Patients With Suspected Chronic Pancreatitis

open access: gold, 2020
Christie Y. Jeon   +8 more
openalex   +1 more source

Human Cyclophilins—An Emerging Class of Drug Targets

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Cyclophilins are a family of enzymes with peptidyl‐prolyl isomerase activity found in all cells of all organisms. To date, 17 cyclophilin isoforms have been identified in the human body, participating in diverse biological processes. Consequently, cyclophilins have emerged as promising targets for drug development to address a wide array of ...
Katarina Jurkova   +3 more
wiley   +1 more source

Nutrient-sensing alteration leads to age-associated distortion of intestinal stem cell differentiating direction

open access: yesNature Communications
Nutrient-sensing pathways undergo deregulation in aged animals, exerting a pivotal role in regulating the cell cycle and subsequent stem cell division.
Zihua Yu   +9 more
doaj   +1 more source

Multiparametric MRI to Predict Response to Irreversible Electroporation Plus Anti‐PD‐1 Immunotherapy in Pancreatic Ductal Adenocarcinoma

open access: yesMagnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To investigate contrast‐enhanced T1‐weighted MRI and diffusion‐weighted magnetic resonance imaging (DWI) for early prediction of tumor response to combined irreversible electroporation (IRE) and anti‐PD‐1 immunotherapy. Methods Murine pancreatic ductal adenocarcinoma (PDAC) cells KRAS* were inoculated into the pancreas of C57BL/6 mice.
Qizhen Cao   +9 more
wiley   +1 more source

Acute pancreatitis: mechanisms and therapeutic approaches

open access: yesSignal Transduction and Targeted Therapy
Acute pancreatitis is a complex inflammatory condition characterized by sudden onset and rapid progression, with severe cases often associated with high mortality.
Qian Hu   +9 more
doaj   +1 more source

Outcomes of delayed endoscopic retrograde cholangiopancreatography in patients with acute biliary pancreatitis with cholangitis

open access: gold, 2020
Paramin Muangkaew   +6 more
openalex   +1 more source

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